TW202317149A - 富含白胺酸之重複激酶２（ＬＲＲＫ２）ｉＲＮＡ藥劑組合物及其使用方法 - Google Patents

富含白胺酸之重複激酶２（ＬＲＲＫ２）ｉＲＮＡ藥劑組合物及其使用方法 Download PDF

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TW202317149A
TW202317149A TW111124391A TW111124391A TW202317149A TW 202317149 A TW202317149 A TW 202317149A TW 111124391 A TW111124391 A TW 111124391A TW 111124391 A TW111124391 A TW 111124391A TW 202317149 A TW202317149 A TW 202317149A
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nucleotides
dsrna agent
strand
dsrna
agent according
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TW111124391A
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Chinese (zh)
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藍 泰 宏 丹
詹母士 Ｄ 馬克辛尼克
馬克 Ｋ 史齊歌
亞當 克斯拓雷諾
圖顏 Ｍ 谷顏
喬瑟夫 拜瑞
馬修 史翠科司
莎拉 樂布朗
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美商艾拉倫製藥公司
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TW111124391A 2021-06-29 2022-06-29 富含白胺酸之重複激酶２（ＬＲＲＫ２）ｉＲＮＡ藥劑組合物及其使用方法 TW202317149A (zh)

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US202163216119P 2021-06-29 2021-06-29
US63/216,119 2021-06-29
US202263353953P 2022-06-21 2022-06-21
US63/353,953 2022-06-21

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US (1) US20240301426A1 (https=)
EP (1) EP4363588A1 (https=)
JP (1) JP2024528503A (https=)
KR (1) KR20240033237A (https=)
AU (1) AU2022303358A1 (https=)
BR (1) BR112023027446A2 (https=)
CA (1) CA3225740A1 (https=)
CL (3) CL2023003984A1 (https=)
CO (1) CO2023018579A2 (https=)
IL (1) IL309548A (https=)
MX (1) MX2024000065A (https=)
TW (1) TW202317149A (https=)
WO (1) WO2023278607A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024238385A2 (en) * 2023-05-12 2024-11-21 Alnylam Pharmaceuticals, Inc. Single-stranded loop oligonucleotides
CN121712891A (zh) * 2023-06-20 2026-03-20 阿达尔克斯制药有限公司 Lrrk2调节组合物及其使用方法
AU2024353921A1 (en) 2023-09-27 2026-04-16 Neuro3 Therapeutics (Suzhou) Ltd. Novel sirna constructs, therapeutics, and modifications
CN120082552A (zh) * 2023-12-01 2025-06-03 艾码生物科技(南京)有限公司 初级-miRNA及其应用

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* Cited by examiner, † Cited by third party
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WO2014110205A1 (en) * 2013-01-11 2014-07-17 Children's Medical Center Corporation Methods and compositions for the production of sirnas
TWI833770B (zh) * 2018-06-27 2024-03-01 美商Ionis製藥公司 用於減少 lrrk2 表現之化合物及方法

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CL2025000168A1 (es) 2025-05-30
KR20240033237A (ko) 2024-03-12
JP2024528503A (ja) 2024-07-30
WO2023278607A1 (en) 2023-01-05
MX2024000065A (es) 2024-02-23
CL2025003326A1 (es) 2026-02-20
IL309548A (en) 2024-02-01
AU2022303358A1 (en) 2024-01-18
BR112023027446A2 (pt) 2024-03-12
CL2023003984A1 (es) 2024-08-16
EP4363588A1 (en) 2024-05-08
CA3225740A1 (en) 2023-01-05
US20240301426A1 (en) 2024-09-12
CO2023018579A2 (es) 2024-01-15

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