TW202245750A - 治療神經性病變疼痛之方法 - Google Patents

治療神經性病變疼痛之方法 Download PDF

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Publication number
TW202245750A
TW202245750A TW111111744A TW111111744A TW202245750A TW 202245750 A TW202245750 A TW 202245750A TW 111111744 A TW111111744 A TW 111111744A TW 111111744 A TW111111744 A TW 111111744A TW 202245750 A TW202245750 A TW 202245750A
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TW
Taiwan
Prior art keywords
fluorophenyl
methyl
phenyl
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
TW111111744A
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English (en)
Chinese (zh)
Inventor
趙媛
翰墨許 奈克
Original Assignee
美商百健Ma公司
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Filing date
Publication date
Application filed by 美商百健Ma公司 filed Critical 美商百健Ma公司
Publication of TW202245750A publication Critical patent/TW202245750A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW111111744A 2018-04-16 2019-04-16 治療神經性病變疼痛之方法 TW202245750A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862658347P 2018-04-16 2018-04-16
US62/658,347 2018-04-16

Publications (1)

Publication Number Publication Date
TW202245750A true TW202245750A (zh) 2022-12-01

Family

ID=68239826

Family Applications (2)

Application Number Title Priority Date Filing Date
TW111111744A TW202245750A (zh) 2018-04-16 2019-04-16 治療神經性病變疼痛之方法
TW108113193A TWI803619B (zh) 2018-04-16 2019-04-16 治療神經性病變疼痛之方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW108113193A TWI803619B (zh) 2018-04-16 2019-04-16 治療神經性病變疼痛之方法

Country Status (14)

Country Link
US (1) US20210154170A1 (enExample)
EP (1) EP3781157A4 (enExample)
JP (1) JP2021521227A (enExample)
KR (1) KR20210002472A (enExample)
CN (1) CN112367990A (enExample)
AU (1) AU2019255519A1 (enExample)
BR (1) BR112020021101A2 (enExample)
CA (1) CA3093401A1 (enExample)
EA (1) EA202092482A1 (enExample)
IL (1) IL277962A (enExample)
MX (1) MX2020010929A (enExample)
SG (1) SG11202008681PA (enExample)
TW (2) TW202245750A (enExample)
WO (1) WO2019204136A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections
CN117899072B (zh) * 2023-12-22 2026-07-28 广州市朝利良生物科技有限公司 一种钠离子通道抑制剂在制备促进伤口愈合药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69733081T2 (de) * 1996-08-23 2006-05-11 Endo Pharmaceuticals Inc. (n.d.Ges.d. Staates Delaware) Antikonvulsive mitteln enthaltende zubereitung zur behandlung von neuropathischen schmerzen
TW200730494A (en) * 2005-10-10 2007-08-16 Glaxo Group Ltd Novel compounds
GB201409851D0 (en) * 2014-06-03 2014-07-16 Convergence Pharmaceuticals Diagnostic method
GB201417497D0 (en) * 2014-10-03 2014-11-19 Convergence Pharmaceuticals Novel use
SG11201903667XA (en) * 2016-11-02 2019-05-30 Biogen Inc Novel dosage regimen

Also Published As

Publication number Publication date
AU2019255519A1 (en) 2020-10-01
CA3093401A1 (en) 2019-10-24
EA202092482A1 (ru) 2021-03-30
CN112367990A (zh) 2021-02-12
WO2019204136A1 (en) 2019-10-24
TWI803619B (zh) 2023-06-01
IL277962A (en) 2020-11-30
EP3781157A4 (en) 2022-01-26
BR112020021101A2 (pt) 2021-02-23
EP3781157A1 (en) 2021-02-24
MX2020010929A (es) 2020-11-06
KR20210002472A (ko) 2021-01-08
SG11202008681PA (en) 2020-10-29
JP2021521227A (ja) 2021-08-26
US20210154170A1 (en) 2021-05-27
TW201946619A (zh) 2019-12-16

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