TW202241351A - Blood separation device - Google Patents

Abstract

The present invention relates to a blood separation device and has a barrel, a cover and a pushing assembly. The barrel has an upper opening, a lower opening and a cavity. The upper and lower openings are respectively covered by the cover and the pushing assembly. The pushing assembly is moveably mounted in the barrel and has a piston fitted tightly in the barrel and a pusher connected to the piston. After the blood separation device with blood is processed by a centrifugation device, a platelet layer is occurred in the barrel. The user directly uses the pusher to push the piston and the platelet layer is extracted therefrom. The blood separation device of the present invention is a very stable and convenient to use.

Description

blood separation device

The invention relates to a blood separation device, in particular to a blood centrifugal device for separating blood by centrifugation.

Platelet Rich Plasma (Platelet Rich Plasma, PRP) is the use of autologous blood through centrifugation to divide the blood into three layers: plasma layer, platelet layer and blood cell layer. The platelet layer is rich in high concentrations of platelets, lymphocytes, Growth factors and a small amount of stem cells, called platelet-rich plasma, have extremely high research value and are widely used in surgical operations, medical cosmetology, sports injury treatment, and accelerated burn and scald treatment.

At present, there is no convenient and fast way to prepare platelet-rich plasma. The platelet-rich plasma in the prior art is usually prepared manually, but there are many types of preparation tools and complicated steps, which are difficult to use. Therefore, it is necessary to improve the existing preparation tools for platelet layer.

In view of the numerous and complicated tools for preparing platelet-rich plasma, the main purpose of the present invention is to provide a stable and easy-to-operate blood separation device.

The main technical means used to achieve the above purpose is to make the blood separation device include: A body tube, which is cylindrical and includes an upper opening, a lower opening, and a centrifugal space communicating with the upper and lower openings; wherein an outer wall of the body tube forms a first thread corresponding to the lower opening; a cover that fits over the upper opening of the body tube; and A propulsion assembly, which is movably arranged on the outer tube wall of the body tube, and includes: a piston, fastened to an inner tube wall of the body tube, to be received in the centrifugal space and adjacent to the lower opening, and comprising an annular recess; and A propeller is connected with the piston and pushes the piston to move toward the upper opening in the centrifugal space of the body tube, including: a bottom plate; An inner cylinder is integrally formed on the bottom plate, and its free end forms an annular convex portion corresponding to the annular concave portion of the piston, and is engaged with the annular concave portion of the piston; An outer cylinder is integrally formed on the bottom plate and coaxially arranged with the inner cylinder to form a rotating space with the inner cylinder, and a second screw thread is formed on the inner side of the outer cylinder corresponding to the rotating space , to be screwed to the first thread of the outer pipe wall of the body pipe; wherein the second thread is longer than the first thread.

It can be seen from the above description that the blood separation device of the present invention is mainly provided with a propulsion assembly directly at the lower opening of its main body tube, and the propulsion assembly can move relative to the main body tube; therefore, when the blood separation device of the present invention is added to the blood After the centrifugal space is centrifuged, just move the propeller directly to push the piston in the centrifugal space, and smoothly extract the platelet layer produced in the centrifugal space after centrifugation, which is quite stable and convenient to use .

The present invention is aimed at improving the blood separation device, and describes the technical content of the present invention in detail with examples and drawings.

First please refer to FIG. 1 , which is an embodiment of the blood separation device 1 of the present invention, which includes a main tube 10 , a cover 20 and a propulsion assembly 30 .

Please refer to Fig. 2, the above-mentioned body pipe 10 comprises an upper opening 11, a lower opening 12 and a centrifugal space 13; The openings 12 are respectively located at two ends of the main body tube 10, the centrifugal space 13 is located between the upper opening 11 and the lower opening 12, and the outer tube wall 15 of the main body tube 10 is formed near the lower opening 12 to form a first A thread 151 forms a third thread 152 near the upper opening 11; in this embodiment, as shown in Figure 3, the diameter D1 of the upper opening 11 is greater than the diameter D2 of the lower opening 12, and the inner pipe wall 14 A conical mouth 141 is further formed near the upper opening 11, wherein the conical mouth 141 includes a liquid intake 143 and communicates with the centrifugal space 13; the inner wall of the conical mouth 141 protrudes inward to form a ring shaped limiting portion 142 . In yet another embodiment, the main body tube 10 can be made of transparent material, so as to facilitate viewing of the contents inside the tube.

Please refer to Fig. 2 and Fig. 3, the above-mentioned cover body 20 is to cover the upper opening 11 of the body tube 10; An annular vertical portion 22; wherein the horizontal portion 21 covers the opening 11 on the main body tube 10, and a perforation 211 is formed corresponding to the liquid intake port 143 of the main body tube 10, and the inner wall of the annular vertical portion 22 is A fourth thread 221 is formed to be screwed with the third thread 152 of the outer pipe wall 15 of the body pipe 10; the cover 20 further includes a sealing member 23, which is rotatably arranged on the top surface of the horizontal portion 21 , so as to pass through the perforation 211 and seal the liquid intake port 143 of the conical mouth 141 . In this embodiment, in order to make the sealing member 23 rotatably arranged on the top surface of the horizontal portion 21, a fixing groove 212 is further formed on the top surface of the horizontal portion 21, and the sealing member 23 extends a connecting section 231 laterally. , the free end of the connecting section 231 corresponds to the fixing groove 212 to form a fixing hole 232, after the fixing groove 212 is aligned with the fixing hole 232, a bolt 233 passes through the fixing hole 232, and then inserted into the fixing groove 212 Fixed, when the sealing member 23 is removed from the perforation 211, it can still be installed on the cover body 20 without falling, which is convenient for use; in addition, the sealing member 23 can further extend a grasping portion 234 laterally for easy use Or pass the sealing member 23 through the through hole 211 to cover the liquid intake port 143 , or pull it out from the through hole 211 .

Please refer to FIG. 2 and FIG. 3 , the above-mentioned propulsion unit 30 is movably disposed on the outer tube wall 15 of the body tube 10 , and the propulsion unit 30 includes a piston 31 and a propeller 32 .

The above-mentioned piston 31 is fastened to the inner tube wall 14 of the body tube 10 to be accommodated in the centrifugal space 13 and close to the lower opening 12; in this embodiment, as shown in Figures 1 and 3, the piston 31 The initial position is to make its top surface close to the marking line position of the "0" scale of the body tube 10, and as shown in Figures 2 and 3, it includes a tight fitting part 311 and a buckle part 312, wherein the tight fitting part 311 The matching part 311 is fastened to the inner tube wall 14 of the main body tube 10, and the buckle part 312 is integrally formed on the bottom surface of the tight fitting part 311, because the outer diameter of the buckle part 312 is smaller than the tight fitting part 311, so it keeps a distance from the inner tube wall 14, instead of tightly fitting on the inner tube wall 14, an annular concave portion 313 can be formed on its outer side; in addition, the buckle portion 312 can further have an outer diameter A conical shape tapered downwards, and a cylindrical hole 314 can be formed upward from the bottom surface of the buckling portion 312 , and the cylindrical hole 314 passes through the buckling portion 312 and part of the fitting portion 311 .

The propeller 32 is connected to the piston 31 and screwed to the first thread 151 of the body pipe 10; Cylinder 323 and a rotating space 324, wherein the inner cylinder 322 is integrally formed on the inner peripheral edge of the base plate 321, and the outer cylinder 323 is integrally formed on the outer peripheral edge of the base plate 321, so as to be integrated with the inner column The body 322 is arranged coaxially. In addition, the free end of the inner cylinder 322 forms an annular protrusion 325, and the length of the outer cylinder 323 is greater than the length of the inner cylinder 322, and the outer cylinder 323 and the inner cylinder 322 form the Rotating space 324, the inner side of the rotating space 324 corresponding to the outer cylinder 323 forms a second thread 326, wherein the length of the second thread 326 is longer than the length of the first thread 151; when assembling, the piston 31 is first inserted into the In the propeller 32, the buckle portion 312 of the piston 31 will first touch the annular convex portion 325 of the inner cylinder 322, and the tapered surface of the buckle portion 312 continues to move downward until the annular convex portion 325 engages. The annular concave portion 313 on the outside of the buckle portion 312 of the piston 31, and the cylindrical hole 314 of the buckle portion 312 is slightly retracted during the movement of the piston 31, which helps the annular convex portion 325 to engage with the piston 31 of the annular recess 313. Then, the longer outer cylinder 323 of the propeller 32 is screwed with the first thread 151 of the outer pipe wall 15 of the body pipe 10 by the second thread 326 and continues to rotate, as shown in FIG. 3 , the piston 31 During the rotation process, the lower opening 12 of the body tube 10 enters the centrifugal space 13 until its top surface is close to the mark line position of the "0" scale of the body tube 10; at this time, the lower end of the body tube 10 enters In the rotation space 324 , but still maintain a travel distance L1 with the bottom plate 321 .

The above is a description of the structure of the blood separation device 1 of the present invention when it is assembled and not in use. The following further introduces how to use the blood separation device 1 to prepare platelet rich plasma (Platelet Rich Plasma, PRP).

First, as shown in FIG. 4A, the user pulls the sealing member 23 away from the perforation 211, so that the liquid intake port 143 is exposed at the upper opening 11. At this time, only the blood 40 containing the anticoagulant is injected into the syringe 50. Insert the needle 51 into the liquid intake port 143 of the main body tube 10, inject blood 40 towards the centrifugal space 13, pull out the syringe 50 after completion, and then cover the sealing member 23 back to seal the liquid intake port 143; then, the The blood separation device 1 is put into a centrifuge to perform a centrifugal layering procedure.

As shown in Figure 4B, after the centrifugation and stratification of the blood from the device 1 is completed, the blood 40 is stratified into a plasma layer 41, a platelet layer 42 and a blood cell layer 43; wherein the blood cell layer 43 is composed of red blood cells and white blood cells composition.

As shown in Figure 4C, before the platelet 42 is taken out, the upper plasma layer 41 needs to be transferred to obtain it. The operation sequence is to remove the sealing member 23 of the cover 10 first, and then put a brand new one. The needle 61 of the syringe 60 is tightly inserted into the liquid intake port 143, and stops at the annular stopper 142. Then, the user takes the blood separation device 1 and turns to the back of the hollow tube 10 to see the 1.0 scale , and then rotate the propulsion assembly 30 of the blood separation device 1 to shorten the travel distance L1' of the rotation space 324 of the propeller 32, and at the same time, the propeller 32 pushes the piston 31 to move up the piston 31, so that blood cells Layer 43 comes to the marking line position of the "1.0" scale. At this time, the plasma layer 41 is squeezed and transferred into the syringe 60 as the piston 31 moves up. The blood separation device 1 is placed on the table, and the The syringe 60 is withdrawn.

Finally, as shown in Figure 4D, the needle 71 of a brand-new syringe 70 is re-inserted tightly into the liquid intake port 143, and then, the user takes the blood separation device 1 and rotates the propulsion assembly 30 to make the platelet layer 42 and the blood cell layer 43 continue to move upward until only the blood cell layer 43 exists in the liquid intake port 143, which means that the platelet layer 42 has successfully entered the syringe 70; so far the platelet layer 42 has been completely taken out.

To sum up, the blood separation device of the present invention mainly uses the propulsion component to be movably arranged on the outer tube wall of the main body tube. The user only needs to rotate the propeller of the propulsion component to push the piston and separate the centrifugal layers. After the blood is transferred in sequence, the required platelet-rich plasma layer can be obtained, and the structure is simple and convenient for users to operate; in addition, the blood separation device of the present invention can easily and conveniently separate the platelet-poor plasma layer, the platelet-rich plasma layer, and the platelet-rich plasma layer. While the plasma layer and the blood cell layer are separated, the generation of medical waste can also be reduced.

The above description is only an embodiment of the present invention, and does not limit the present invention in any form. Although the present invention has been disclosed as above with the embodiment, it is not intended to limit the present invention. Anyone with ordinary knowledge in the technical field, Within the scope of not departing from the technical solution of the present invention, when the technical content disclosed above can be used to make some changes or be modified into equivalent embodiments with equivalent changes, but all the content that does not depart from the technical solution of the present invention, according to the technical essence of the present invention Any simple modifications, equivalent changes and modifications made to the above embodiments still fall within the scope of the technical solution of the present invention.

1: Blood separation device 10: Body tube 11: Upper opening 12: Lower opening 13: centrifugal space 14: Inner pipe wall 141: Conical mouth 142: Ring limit part 143: Liquid intake port 15: Outer pipe wall 151: first thread 152: The third thread 20: cover body 21: Horizontal Department 211: perforation 212: fixed slot 22: ring vertical part 221: The fourth thread 23: Seals 231: Connection section 232: fixed perforation 233: plug 234: grabbing department 30:Propulsion components 31: Piston 311: Fitting part 312: buckle part 313: Annular recess 314: cylindrical hole 32: Thruster 321: Bottom plate 322: inner cylinder 323: Outer cylinder 324:Rotation space 325: ring convex part 326: second thread 40: blood 41: plasma layer 42: Platelet layer 43: blood cell layer 50, 60, 70: syringe 51: Injection needle 61, 71: Needle

Figure 1: A perspective view of an embodiment of the blood separation device of the present invention. Figure 2: An exploded perspective view of Figure 1. Figure 3: A side sectional view of Figure 1. 4A to 4D: Schematic diagrams of the operation of the blood separation device of the present invention.

1: Blood separation device

10: Body tube

13: centrifugal space

20: cover body

23: Seals

30:Propulsion components

32: Thruster

Claims (10)

A blood separation device comprising: A body tube, which is cylindrical and includes an upper opening, a lower opening, and a centrifugal space communicating with the upper and lower openings; wherein an outer wall of the body tube forms a first thread corresponding to the lower opening; a cover that fits over the upper opening of the body tube; and A propulsion assembly is movably mounted on the outer wall of the body tube and includes: a piston, fastened to an inner tube wall of the body tube, to be accommodated in the centrifugal space and adjacent to the lower opening, and comprising an annular recess; and A propeller is connected with the piston and pushes the piston to move toward the upper opening in the centrifugal space of the body tube, including: a bottom plate; An inner cylinder is integrally formed on the bottom plate, and its free end forms an annular protrusion corresponding to the annular recess of the piston, and is engaged with the annular recess of the piston; and An outer cylinder is integrally formed on the bottom plate and coaxially arranged with the inner cylinder to form a rotating space with the inner cylinder, and a second screw thread is formed on the inner side of the outer cylinder corresponding to the rotating space , to be screwed to the first thread of the outer pipe wall of the body pipe; wherein the second thread is longer than the first thread. The blood separation device as claimed in item 1, wherein the piston includes: a tight fit part, fastened to the inner tube wall of the body tube; and A buckle part is integrally formed on the bottom surface of the tight fit part, and the outer diameter of the buckle part is smaller than that of the tight fit part, and the annular concave part is recessed on the outside of the buckle part. The blood separation device according to claim 2, wherein the buckle part is in the shape of a cone whose outer diameter tapers downward, and a cylindrical hole is formed upward from the bottom surface of the buckle part, and the cylindrical hole runs through the buckle Department and part tight fitting department. The blood separation device according to claim 2 or 3, wherein the length of the inner cylinder is shorter than the length of the outer cylinder. The blood separation device as described in Claim 4, wherein: The body pipe system further includes a conical mouth integrally formed on the inner pipe wall and close to the upper opening, and the conical mouth includes a liquid intake port; and The cover system is in the shape of a ㄇ and includes: a horizontal part, which covers the upper opening and forms a perforation corresponding to the liquid intake port of the conical mouth; an annular vertical portion extending downward from the outer periphery of the horizontal portion and fixed to the outer wall of the body tube; and A sealing member is rotatably arranged on the top surface of the horizontal part to pass through the perforated sleeve and seal the liquid intake port of the conical mouth. The blood separation device as described in Claim 5, wherein: A fixing groove is formed on the top surface of the horizontal portion; and A connecting section extends laterally from the sealing member, and a fixing through hole is formed at the free end of the connecting section corresponding to the fixing groove, and a bolt is inserted into the fixing through hole and the fixing groove. The blood separation device according to claim 6, wherein the outer wall of the body tube forms a third thread corresponding to the position of the upper opening, and the inner wall of the annular vertical part forms a fourth thread corresponding to the third thread , to be screwed on the outer tube wall of the body tube. The blood separation device according to claim 7, wherein the diameter of the upper opening is larger than the diameter of the lower opening. The blood separation device as claimed in claim 8, wherein the sealing member further extends laterally with a grasping portion. The blood separation device according to Claim 4, wherein the inner wall of the liquid intake port of the conical mouth forms an annular stopper.

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