TW202043229A - 雙環酮化合物及其使用方法 - Google Patents

雙環酮化合物及其使用方法 Download PDF

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Publication number
TW202043229A
TW202043229A TW109100698A TW109100698A TW202043229A TW 202043229 A TW202043229 A TW 202043229A TW 109100698 A TW109100698 A TW 109100698A TW 109100698 A TW109100698 A TW 109100698A TW 202043229 A TW202043229 A TW 202043229A
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Taiwan
Prior art keywords
disease
compound
patent application
scope
item
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TW109100698A
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English (en)
Chinese (zh)
Inventor
史納黑爾 派托爾
葛羅葛瑞 漢米爾頓
桂玲 趙
慧芬 陳
布萊克 丹尼爾斯
克雷格 史迪瓦拉
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瑞士商赫孚孟拉羅股份公司
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Publication of TW202043229A publication Critical patent/TW202043229A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW109100698A 2019-01-11 2020-01-09 雙環酮化合物及其使用方法 TW202043229A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962791118P 2019-01-11 2019-01-11
US62/791,118 2019-01-11

Publications (1)

Publication Number Publication Date
TW202043229A true TW202043229A (zh) 2020-12-01

Family

ID=69528972

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109100698A TW202043229A (zh) 2019-01-11 2020-01-09 雙環酮化合物及其使用方法

Country Status (7)

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US (2) US12344612B2 (enExample)
EP (1) EP3908586B1 (enExample)
JP (1) JP7585205B2 (enExample)
CN (1) CN113302193A (enExample)
AR (1) AR119673A1 (enExample)
TW (1) TW202043229A (enExample)
WO (1) WO2020146615A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
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KR20230165238A (ko) * 2021-04-02 2023-12-05 제넨테크, 인크. 비시클릭 케톤 화합물 제조 공정
WO2023225041A1 (en) * 2022-05-19 2023-11-23 Merck Sharp & Dohme Llc Ripk1 inhibitors and methods of use

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Also Published As

Publication number Publication date
AR119673A1 (es) 2022-01-05
JP2022516651A (ja) 2022-03-01
CN113302193A (zh) 2021-08-24
EP3908586B1 (en) 2022-12-21
US20250282788A1 (en) 2025-09-11
EP3908586A1 (en) 2021-11-17
US20210340151A1 (en) 2021-11-04
JP7585205B2 (ja) 2024-11-18
US12344612B2 (en) 2025-07-01
WO2020146615A1 (en) 2020-07-16

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