TW201538078A - Household insecticide effervescent tablet and preparation method thereof - Google Patents

Abstract

A household insecticide effervescent tablet is provided, particularly relating to a household insecticide effervescent tablet that contains imidacloprid and a preparation method thereof. The disclosed household insecticide effervescent tablet containing imidacloprid provides advantages including a convenient insecticide application, a quick and exact drug efficacy, low residue, non-pollutant environmental pollution, and a very convenient and simple way to transport and store.

Description

Household insecticide foaming ingot and preparation method thereof

The present invention relates to a household insecticide foaming ingot, and more particularly to a household insecticide foaming ingot containing imidacloprid, and a process for the preparation thereof.

It is well known that a wide variety of insect species (eg, flies, mosquitoes, cockroaches, ants, etc.) are widely distributed throughout our lives, whether in the interior of the home, in the surrounding courtyard, or even in nearby parks, wherever we live. The environment has an innumerable number of insects present in it. These insects, which form part of the ecosystem, have an indispensable position in maintaining their ecological balance. However, due to their natural nature and living habits, when they come into contact with us, it will inevitably cause our uneasiness. , damage, or even casualties. For example, when cockroaches appear in the home, it not only disturbs the comfort and stability of daily life, causes nervousness, and because the body carries virulence factors (such as germs or viruses), it is contaminated with tableware or food. Afterwards, these virulence factors may be left on the tableware or food, which may further cause infectious diseases and cause harm or death to our people.

Therefore, in order to maintain the stability of life and the health of the body, it is necessary to suppress or eliminate these insects that invade our living circle. Household insecticides, which are one of the environmental drugs, are used to kill mosquitoes, flies, ants, cockroaches... The best weapon for these harmful insects. However, the use of household insecticides must be cautious because the active ingredients of these pesticides have certain The degree of toxicity, if not used properly, can not only effectively remove harmful insects, but may cause environmental pollution and endanger human health. Therefore, excellent household insecticides must have low toxicity, rapid drug efficiency, ease of use, and low residue.

Iidacloprid is a neonicotinoid insecticide in the form of a colorless and odorless crystal. It is mainly used as a neurotoxin of insects, acting on the central nervous system of insects to achieve interference with the nervous system. The effect of internal message transmission leads to insect mites and eventually death, but edamine is less toxic to mammals and can be considered as a household insecticide. It is known that edetamine enters insects through direct contact or ingestion by insects. Therefore, ydamine has good control for sucking or chewing mouthparts such as flies, mosquitoes, cockroaches, ants, etc. effect. According to the study, insects poisoned by edetamine quickly stopped eating, followed by paralysis, convulsions, and death within 24 to 48 hours after poisoning. Because idamine is very toxic to humans, has rapid effects, and is effective in inhibiting or eliminating harmful insects in the home, it is very suitable as an insecticide for household use.

However, at present, the domestic insecticide containing edamine in the market is mainly made up of emulsifiable concentrates and wettable powders. These household insecticide formulations are not only before application. The mixing stage is prone to splashing (such as emulsion) or scattering (such as powder), which causes pollution of the surrounding environment; and its effective dosage is not easy to control when blending, and the pesticide solution that is often prepared is not The effective dose is too low, so the goal of de-worming cannot be achieved, that is, the effective dose is too high, resulting in waste of the cost of de-worming and an increase in the amount of environmental residues. In addition, these household insecticide emulsions and powder dosage forms are bulky and occupy a large space, which is not only time-consuming and labor-intensive in transporting goods, but also requires unnecessary storage space during storage and increases production costs. Therefore, we urgently need a kind of energy Household insecticides that improve the above disadvantages.

The object of the present invention is to provide a household insecticide which is simple in operation, quick in efficacy, low in residual amount, difficult to cause environmental pollution around the environment, and convenient and easy to transport and store, and a preparation method thereof.

The present invention achieves the above object by the following technical means: the present invention provides a household insecticide foaming ingot containing imidacloprid, including, by weight percentage: etatonide powder 3-50%; PEG4000 10 -30%; lactose 15-30%; sodium bicarbonate 15-30%; citric acid 15-30%; and cerium oxide 0.5-5%.

In a preferred embodiment of the present invention, the lindaamine-containing household insecticide foaming ingot comprises, in weight percent, idamaximide powder 3-10%; PEG4000 20-25%; lactose 20 -25%; sodium bicarbonate 20-25%; citric acid 20-25%; and cerium oxide 0.5-2%.

In another preferred embodiment of the present invention, the lindaamine-containing household insecticide foaming ingot comprises, in weight percent, 3% of edamine powder; PEG4000 21.4%; lactose 25%; Sodium hydrogen 25%; citric acid 25%; and cerium oxide 0.6%.

In a preferred embodiment of the invention, the household insecticide foaming ingot containing edaramin is in the shape of a circle or a polygon.

In a preferred embodiment of the present invention, the lindaamine-containing household insecticide foaming ingot can effectively fight and extinguish harmful insects in the family, especially flies, black mosquitoes, cockroaches, red fire ants, termites and flea.

The invention also provides a preparation method of a household insecticide foaming ingot containing imidacloprid, which comprises the following steps (all percentages are percentage by weight, and finally obtained The weight percentage of the household insecticide foaming ingot is 100%): (1) weighing 3-50% of edetamine powder and 10-30% of PEG4000; (2) making the edaramin powder Mixing with the PEG 4000 to obtain a homogeneous mixture; (3) adding 15-30% of the lactose in the homogeneous mixture obtained in the step (2), and mixing to obtain a homogeneous mixture; (4) uniformly obtained in the step (3) To the mixture, 15-30% sodium hydrogencarbonate and 15-30% citric acid are added and mixed to obtain a homogeneous mixture; (5) 0.5-5% of the homogeneous mixture obtained in the step (4) is added. The cerium oxide is mixed and mixed to obtain a homogeneous mixture; (6) the homogeneous mixture obtained in the step (5) is dried; and (7) the dried mixture obtained in the step (6) is subjected to bar forming to obtain A household insecticide foaming ingot containing beneficial amines.

In a preferred embodiment of the present invention, the method for preparing a household insecticide foaming ingot containing idadamine, idamide powder, PEG4000, lactose, sodium hydrogencarbonate, citric acid and cerium oxide The amounts added were 3%, 21.4%, 25%, 25%, 25%, and cerium oxide 0.6% (all percentages are by weight, and the final weight percentage of the household insecticide foaming ingot was 100%).

In a preferred embodiment of the present invention, in the method for preparing a household insecticide foaming ingot containing imidacloprid, the drying treatment in the step (6) is carried out at a temperature of 40 ° C and dried for 4 hours. And finished.

Foamed ingots are used earlier in medicine, but they are an innovative technology in environmental medicine. The invention prepares the composition containing the edaramine insecticide component into a foaming tablet dosage form, and uses the foaming ingot to generate a large amount of gas when it is in contact with water, without the user stirring, the gas driving force causes the foaming ingot to rapidly and completely disintegrate. Releases the active ingredient (IDA) and disperses it evenly in aqueous solution, not The preparation process of household insecticide can be completed simply and quickly, which saves working time and improves work efficiency compared with conventional emulsions or wettable powders; and because of the use of solid dosage forms, it can be avoided when preparing the preparation. The insecticide emulsion splashes or the insecticide powder flies around, causing environmental pollution.

Furthermore, since the dose of the active ingredient (IDA) in the tablet has been previously fixed, it is only necessary to throw the insecticide foam ingot into a predetermined volume of water during the preparation, and also prevent the above-mentioned modulation. In the insecticide solution, the active ingredient (IDA) is dosed too high or the dosage is too low.

In addition, since the household insecticide foaming ingot of the present invention is in the form of a solid ingot, it is easy and safe to transport, and the space for storage is small, and since the foamed ingot is a dry solid, it is The physical and chemical properties of the ingredients are quite stable and are not easily deteriorated or deteriorated. Therefore, they have many advantages such as not reducing the efficacy of the drug and extending the shelf life for a long time.

Accordingly, the present invention provides a household insecticide foaming ingot containing imidacloprid, including, by weight percent: etadamine powder 3-50%; PEG 4000 10-30%; lactose 15-30% Sodium bicarbonate 15-30%; citric acid 15-30%; and cerium oxide 0.5-5%. Among them, the idalant powder system is used as an effective active ingredient for the elimination of harmful insects. An alkaline action component of a sodium hydrogencarbonate foaming ingot, an acidic component of a citric acid foaming ingot, and an acid-base neutralization reaction of a sodium bicarbonate and a citric acid to produce a carbon dioxide gas characteristic. It can quickly disintegrate in water to form a uniform and effective insecticide solution. Lactose is used as an attractant for harmful insects to attract these harmful insects to approach and suck the insecticide foaming ingot containing edamine, which causes poisoning of these harmful insects and eventually dies. PEG4000 is used as an adhesive for insecticide foaming ingots, which makes the surface of the tablet smooth and shiny and is not easily broken. Dioxide Lanthanide is used as a flow promoter for insecticide foaming ingots, which can improve the fluidity of the particles in the tablet, increase the density of the tablet, increase the hardness of the prepared tablet, shorten the disintegration time, and thereby increase the active ingredient. The dissolution rate of edamine.

In a preferred embodiment of the present invention, the lindaamine-containing household insecticide foaming ingot comprises, in weight percent, idamaximide powder 3-10%; PEG4000 20-25%; lactose 20 -25%; sodium bicarbonate 20-25%; citric acid 20-25%; and cerium oxide 0.5-2%.

In a further preferred embodiment of the present invention, the household insecticide foaming ingot containing edaramin is 2 g, including 0.06 g of edetamine powder; 0.428 g of PEG 4000; 0.5 g of weight Lactose; 0.5 g of sodium bicarbonate; 0.5 g of citric acid; and 0.012 g of cerium oxide. In the preferred embodiment, the amount of sodium bicarbonate and citric acid used in the insecticidal foam ingot is increased to 25% of the weight of the entire household insecticide foaming ingot, so that the rate of formation of bubbles in the solution is increased. Rapidly, the disintegration of the insecticidal foaming ingot is more complete, and the effective insecticidal component edetamine is spread more quickly and evenly.

In a preferred embodiment of the present invention, the disclosed insecticide foaming ingot containing edamine is in the shape of a round ingot or a polygonal ingot, which is more convenient for the user to transport and store, thereby saving household insecticidal activity. The production cost of the agent.

In a preferred embodiment of the present invention, the disclosed household insecticide foaming ingot containing edamine can effectively extinguish any harmful insects, especially flies, black mosquitoes, cockroaches, red fire ants commonly found in home life. , insects such as termites and fleas.

The invention therefore also provides a method for preparing a household insecticide foaming ingot containing imidacloprid, which comprises the following steps (all percentages are by weight, and finally obtained by weight percentage of the household insecticide foaming ingot) 100%): (1) weighing 3-50% of edaramin Powder and 10-30% PEG4000; (2) mixing the edetamine powder with the PEG 4000 to obtain a homogeneous mixture; (3) adding 15-30% lactose to the homogeneous mixture obtained in the step (2) And mixing to obtain a homogeneous mixture; (4) in the homogeneous mixture obtained in the step (3), adding 15-30% of sodium hydrogencarbonate and 15-30% of citric acid, and mixing to obtain a homogeneous mixture; 5) in the homogeneous mixture obtained in the step (4), adding 0.5-5% of cerium oxide and mixing to obtain a homogeneous mixture; (6) drying the homogeneous mixture obtained in the step (5); and (7) The uniformly dried mixture of the step (6) is subjected to tableting to obtain a household insecticide foamed ingot containing edetamine.

Hereinafter, the present invention will be described by way of a specific embodiment: weighing 0.06 g of yodamine powder (purchased from China Red Sun Co., Ltd.) and 0.428 g of PEG 4000 (purchased from Taiwan No. 1 Chemical Materials Co., Ltd.) The two are set at a temperature of 25 degrees to 27 degrees Celsius and a relative humidity of 45% to 55%. The model TS-101 mixer (made by Taiwan Tim Shuo Food Machinery Co., Ltd.) is set at 1/3 HP of horsepower and the speed is set 150 times per minute. Next, the 0.06 g of the estamide powder was stirred and mixed with the 0.428 g PEG 4000 for a stirring time of 20 minutes, and the resulting mixture exhibited a completely homogeneous mixture.

Then, maintaining the same temperature and relative humidity, 0.5 g of lactose (purchased from Taiwan No. 1 Chemical Materials Co., Ltd.) was added to the previously mixed mixture of edamine powder and PEG 4000, and the model TS- was used. The 101 mixer (manufactured by Taiwan Tim Shuo Food Machinery Co., Ltd.) was stirred and mixed at a setting of 1/3 HP of horsepower and 150 times per minute. The stirring time was 20 minutes, and a completely uniform mixed product was obtained.

Then, maintaining the same temperature and relative humidity, and then uniformly mixing the above products, adding 0.5 g of sodium bicarbonate (purchased from Taiwan Bailu Technology Biochemical Co., Ltd.) and 0.5 g Kezhong citric acid (purchased from Taiwan Bailu Technology Biochemical Co., Ltd.), and using the model TS-101 mixer (made by Taiwan Timuo Food Machinery Co., Ltd.) to stir and mix at 1/3 HP of horsepower and 150 times per minute. The stirring time was 20 minutes, and as a result, a completely homogeneous mixed product was obtained.

Then, maintaining the same temperature and relative humidity, 0.012 g of cerium oxide (purchased from Taiwan First Chemical Materials Co., Ltd.) was added to the above mixed product, and the model TS-101 mixer (Taizhou Tianshuo Food Machinery) was used. Co., Ltd. manufactured) The mixture was stirred at a horsepower of 1/3 HP and the rotation speed was set at 150 times per minute. The stirring time was 20 minutes, and a completely uniform mixed product was obtained.

The resulting final homogeneous mixed product was placed in a hot air dryer (manufactured by Taiwan Yuyu Enterprise Co., Ltd.), and dried at a temperature of 40 ° C for 4 hours.

Finally, the above-mentioned dried mixed product is subjected to high-pressure ingot molding using a rotary type ingot machine of the model KJ-RT-12 (manufactured by Taiwan Minjin Machinery Co., Ltd.) (rotation speed is set to 30 revolutions per minute), thus, A 2 gram weight of household insecticide foamed ingot containing edamine is obtained.

It is to be understood that the specific embodiments described in the specification are merely for the purpose of illustrating the technical features of the present invention, and are not intended to limit the scope of the present invention. Various modifications and changes of the present invention are possible without departing from the scope of the invention.

Claims (9)

A household insecticide foaming ingot containing imidacloprid, including, by weight percent: etatonide powder 3-50%; PEG4000 10-30%; lactose 15-30%; sodium bicarbonate 15 -30%; citric acid 15-30%; and cerium oxide 0.5-5%. A household insecticide foaming ingot containing idamine as claimed in claim 1, comprising, by weight percentage: ideamine powder 3-10%; PEG 4000 20-25%; lactose 20-25%; sodium hydrogencarbonate 20-25%; citric acid 20-25%; and cerium oxide 0.5-2%. A household insecticide foaming ingot containing idamine as claimed in claim 2, comprising, by weight percent: 3% of edamine powder; 21.4% of PEG 4000; 25% of lactose; 25% of sodium hydrogencarbonate; %;and Ceria is 0.6%. A household insecticide foaming ingot containing the idadamine of claim 1, wherein the foamed ingot has a circular or polygonal shape. A household insecticide foaming ingot containing idamine as claimed in claim 1 for extinguishing flies, black mosquitoes, cockroaches, red fire ants, termites and fleas. A method for preparing a household insecticide foaming ingot containing imidacloprid, comprising the following steps (all percentages are percentage by weight, and finally the weight percentage of the household insecticide foaming ingot is 100%): 1) weighing 3-50% of edetamine powder and 10-30% of PEG4000; (2) mixing the edaramin powder with the PEG4000 to obtain a homogeneous mixture; (3) obtaining in step (2) In a homogeneous mixture, 15-30% lactose is added and mixed to obtain a homogeneous mixture; (4) in the homogeneous mixture obtained in the step (3), 15-30% sodium hydrogencarbonate and 15-30% are added. Citric acid, and mixed to obtain a homogeneous mixture; (5) in the homogeneous mixture obtained in the step (4), 0.5-5% of cerium oxide is added and mixed to obtain a homogeneous mixture; (6) the step (5) The resulting homogeneous mixture is subjected to a drying treatment; and (7) the dried homogeneous mixture of the step (6) is subjected to tableting to obtain the household insecticide foaming ingot containing edaramine. The method for preparing a household insecticide foaming ingot containing etadine of claim 6, wherein the amount of edetamine powder, PEG4000, lactose, sodium hydrogencarbonate, citric acid and cerium oxide is 3%, respectively. 21.4%, 25%, 25%, 25% and cerium oxide 0.6%. The method for preparing a household insecticide foaming ingot containing etadine according to claim 6, wherein the drying treatment in the step (6) is carried out at a temperature of 40 ° C and drying for 4 hours. The method for preparing a household insecticide foaming ingot containing idamide according to claim 7, wherein the drying treatment of the step (6) is carried out at a temperature of 40 ° C for 4 hours.