JPS6042314A - Mite-controlling composition - Google Patents

Abstract

PURPOSE:To provide a mite-controlling composition containing resmethrin and benzyl benzoate as active components, and having extremely excellent synergistic miticidal activity and high safety. CONSTITUTION:The objective mite-controlling composition contains (A) 1pt. of resmethrin (including isomers) and (B) >=0.5pts., preferably >=1pt. of benzyl benzoate which has high safety to enable the use in food preparation. The composition exhibits sure miticidal effect to various mites living in the TATAMI mat, carpet, food storage, human body, animal body, plant, etc., and accordingly surely prevents the bite and bloodsucking by the mite and allergic diseases caused thereby. Although the composition can be used as it is, however, it is preferable to apply in the form of a liquid or solid using a proper carrier or other additive, by placing, scattering, spraying, coating, pasting, etc.

Description

[Detailed description of the invention] The present invention relates to a mite control composition.

Among the 11 indoor mites from Tsuchiki, dust mites (or former tl+onyssus) are among the ones that cause important harm to humans.
bacoLi) was well known. However, in recent years, allergy and insect bites have become a problem due to the presence of dust mites and dust mites that prey on these mites.
Have any attempts been made to control these mites B'il, such as 41-phosphorus insecticides, Carbuff-1-based insecticides, and pyrethroid insecticides, which have traditionally been used to control pests?
None of these methods are decisive for controlling insect pests, and many use pyrethroid insecticides from a safe distance of 1 m.

It has recently been discovered that resmethrin has an excellent acaricidal effect among the Konohilethroid insecticides. However, when examining the susceptibility of Dermatophagus mites and Dermatophagus mites to resmethrin, it was found that mites are less sensitive to resmethrin.For this reason, attempts have been made to use organic phosphorus agents that are effective against mites, but the effect is insufficient. There were also questions about safety. For these reasons, low-concentration resmethrin treatment is sufficient to kill mites, especially against Dermatophagoides mites that live in indoor dust.
Since resmethrin treatment is not sufficient to kill mites that occur inside bamboo or on food, there is a strong need for a miticide that can be used indoors.

In view of the above-mentioned current situation, the present inventors aimed to provide an excellent acaricide, and as a result of trying to find a highly safe acaricide that can be applied to indoor ticks to keep them young, the inventors found that resmethrin By combining benzyl benzoate (including isomers) and benzyl benzoate, which is also used in foods, we found a more effective mite killing effect and completed the present invention.

That is, the present invention provides a mite control composition containing resmethrin (including isomers) and benzoic acid pencil as its own ingredients.

The acaricidal composition of the present invention contains, as its active ingredients, resmethrin (including the hetero-1-L form) and 1-acid pencil, and therefore has an extremely excellent synergistic effect. .

The acaricidal effect of the present invention can be applied to chiggers, house dust mites, mites, Demodex mites, house dust mites, red mites, red mites,
Bird→) - It is strong against wood mites, claw mites, lice mites, leaf mites, dust mites, sand mites, and black mites.

Therefore, the mite control agent of the present invention is effective against mites, carpeno+-, etc. in the home, food storage areas, human bodies, animals, plants, etc.
By applying this, it exhibits a reliable acaricidal effect against various mites living or parasitic in these places,
Furthermore, it is possible to accurately avoid tick bites, blood sucking, and allergic diseases in animals.◇ In the present invention, the blending ratio of the active ingredients is 1:
It is preferable to self-combine benzyl benzoate Jv1 to resmethrin I.

The mite control composition of the present invention can be applied as it is to areas where mite control is required, but it is usually preferable to use a suitable carrier, candy formulation, etc. to apply the area, application method, etc. It can be prepared and used in various suitable forms, such as liquid preparations and solid preparations. Examples of carriers used in preparing the liquid formulation include water, alcohols such as methyl alcohol and ethyl alcohol, acetone,
Ketones such as methyl ethyl if), esters such as tetrahydrofuran, esters, aliphatic hydrocarbons such as paraffin, kerosene, paraffin, benzine, aromatic carbons such as benzene, toluene, etc. Examples include hydrogen 4'1, esters such as ethyl acetate, and halogenated hydrogen oxides such as dichloroIJ ethane. The liquid form of the tick control agent of the present invention further contains a conventional tick-forming agent,
Additives such as emulsification, dispersion, spreading agent, iM flVI nυ, stabilizer, ISU'1, 1, etc. can be added to the formulation, emulsification, emulsification, emulsion, milking, etc. It can be used in the form of a dispersant, a balm, a lotion, a cream, a spray, an aerosol, and the like. Examples of additives include cellulose derivatives such as 210 cellulone, acetyl cellulose, acetyl butyryl cellulose, and methyl cellulose, vinyl-based +++ compounds such as vinyl acetate resin, anolequinodo-based trees 1, and urea fibers. Tree 1 (effect, evo''
Kishiikiri fat, polyester resin, urethane resin,
Silicone resins, acrylic flats (61 fats, chlorinated rubber, coating film forming agents such as polyvinyl alcohol, soaps, polyoxyethylene J fatty alcohol ethers such as polyoxyethylene oleyl ether, polyoxyethylene such as polyoxyethylene nonyl phenyl ether) Surfactants such as ethylene alkyl allyl ether, polyogine ethylene fatty acid ester, fat ljh acid lyceride, sorbicun fatty acid ester, sulfuric acid ester of higher alcohol, argylyl allyl sulfonate such as sodium benzene sulfonate, etc. 1. Fossil gas, dimethyl ether, propellants such as fluorocarbon, casein, gelatin, alginic acid, CMC, etc. can be exemplified.

In addition, examples of carriers used in preparing a solid form include mineral powders such as silicic acid, kaolin, activated carbon, bentonite, diatomaceous earth, talc, clay, calcium oxate, and ceramic powder; wood powder; Examples include vegetable powders such as soybean flour, wheat flour, and starch, and clathrate compounds such as cyclodextrin. Furthermore, in preparing the cut-and-cut form,
For example, tricyclotecan, cyclotothican, 2.4
．． 6-1-liisoprobyl-1.3.5-trioxane, trimethylenenorformane, etc., and a +1 insect repellent such as paradichlorobenzene, naphthalene, camphor, etc., are used to melt-mix or melt-mix the above composition. It is also possible to mold the mixture after mixing to form a separate solid agent.

The above-mentioned hard potash also includes the shape of a resin molded product obtained by kneading the composition into plastics.

Additionally, it is also possible to use a backing agent of Carpeno 1.

In addition, the mite control composition of the present invention can be prepared into microcapsules according to, for example, a spray drying method using polyvinyl alcohol or MC, an in-liquid curing method using gelatin, polyvinyl alcohol, alginic acid, etc., a core cell benecan method, etc. The converted form Bt was prepared from benzylidene-D-
Gel forms can also be prepared using gelling agents such as sorbitol and carrageenan.

Furthermore, the mite control composition of the present invention may contain known pest repellents, potency enhancers, antioxidants, insecticides, rodent control and repellents, fungicides, repellents, herbicides, fertilizers, and pesticides. Incense criminal, 5
(a) A colorant etc. can be blended.

Other pest repellents that can be blended include N,N-diethyl-meta-toluamide, 2.3.4.5-bis(Δ2-butylene)-tetrahydrofurfural, di-n-propyl, and isocincomero. N-(2-ethylhexyl)-bicyclo-(2,2,1)-5-1ten-2,3 as a potency enhancer. -dicarboximide, 6-(propylbiperonyl)-butylcarbityl ether? Examples of antioxidants include butylhydroxyanisole, dibutylhydroxytoluene,
Tocopherol, r-oryzanol, etc. are used as insecticides, pyrenoloids such as the common name arenuline and its geometric and/or optical isomers are used as insecticides, and α-naphthylthiA urea and cyclobeximi 1 are used as rodent exterminators and repellents. etc., as a swamp killer, salicylic acid, p-chloro-2nol
-xylenol, 2-(4'-thiazoyl)''benzimidazole, etc., and anti-application agents such as α-10monaminoqualdehyde, N-dimethyl-N-phenyl + N'-
Examples include (fluorodichloromethane), thiosulfamide, etc., but are not limited to these.

The mite control composition of the present invention, which has various forms made of:A, is suitable for use in areas where mites live, such as general households, grain warehouses, cafeterias, furniture, and closets where a mite control effect is required. It can be applied by placing, scattering, spraying, applying, pasting, etc. on the entrance, washing area, etc., or by spraying, applying, etc. to the animal body itself.

Furthermore, the mite control composition of the present invention can be applied to a suitable sheet-like base material in advance by applying it, impregnating it, dropping it, kneading it, etc., and then placing it on the desired location in a form that is retained on the base material. It can also be used by pasting together. This one
Examples of sheet materials used in festivals include synthetic resin sheets such as polyethylene, polypropylene, nylon, polyvinyl chloride, polyvinylidene chloride, and polyester;
Animal/plant material or inorganic 1R fibrous sheet paper, cloth, non-woven fabric,
(leather, etc.), mixed sheets or blended fabrics of 2nd grade synthetic 1st fat and inorganic fibers or powder, blended fabrics or non-spread fabrics of the above synthetic fats and dynamic (straight yarn 11), aluminum, stainless steel, Examples include foils or films of metals such as 411 lead and laminated sheets of various types of sheets 1 described in 2.

The amount of the active ingredient mixture in the mite control composition of the present invention and the amount applied of the control composition (well, depending on the dosage form, application method, application location, etc., the legal deviation in the ventricle is good, but is not limited?)
m Normal dispersion f: When used in powder form such as lJ or wettable powders, the active ingredient mixture is 1 to 80% by weight, preferably 5 to 80% by weight.
It is sufficient that the content is 40% by weight, and when it is in the form of a solid bar such as a powder, it may be contained by 1 to 50% by weight, preferably 2 to 2% by weight. ! When the mite-controlling composition of the present invention is kept in a form in which the mite-controlling composition of the present invention is applied, for example, the amount of the saturated compound I such as H (approximately double the amount of nails) may be maintained. 0005~xy as the active ingredient mixture per application surface ft!tly y)i, preferably renunonulin 0.01
g~017, benzoic acid pencil 0.005 g~0.3
From the viewpoint of the acaricidal effect and the irritant nature of the drug, it is appropriate to set it to 1.g.

When used as a solid or other form, the application space 177.1'
It is appropriate for the active ingredient compound to be present in an amount of about 1:1 or more.

The mite control composition of the present invention will be explained in detail below based on Examples and Test Examples.

Examples Predetermined amounts of lusmethrin and benzoic acid pencil were dissolved in acetone, and one graph paper (each) was prepared as shown in the table below.
5 (7) x 5 cm) and air-dried to remove acetone to obtain each notebook-shaped mite control composition.

1 0,01 0.001 2 0,01 0.005 3 0,01. 0.01 4 0,01 0.03 5 Q, OL 0.05 Test Example 1 The kraft paper shown in Actual Artillery Example 1 was treated with terenumenulin alone, Yasuyama, and fragrant pencil alone in the same manner. was tested as a reference.

Processing graph l - Put the paper in a plastic bag and put about 4,005 yen in it.
fl mites, woolly mites, or phyllotid mites were placed in a separate container 4 and sealed. After 24 hours (in the case of Dermatophagoides mites, observation was not allowed even after 72 hours), the mites in the plastic bag were checked for life and death under conditions of vh 11 L, and the mortality rate was ≧. In addition,
Abbot i'+l from the blank fatality rate
Calculated by correcting i.

As a result, -1: As shown in the table, the tick control composition of the present invention obtained in Actual Example 1 clearly had a 4'12 power R4 effect.

Example 2 A mixture of 01 parts of Leffu 9F and 0.28B of Anvaginal Fragrance Pencil was dissolved in 20 parts of acetone, 997 parts of 300 Nonon Yukre was added and stirred thoroughly, and the acetone was distilled off. Inventive mite control composition. A 3% powder was obtained.

Example 3 10 parts of a mixture of 25 parts of resmethrin and 75 parts of benzyl benzoate were added, 15 parts of Q Kotsurpol 3005 (Toho Chemical ■1) (product name), and 75 parts of Kijirol were mixed and dissolved by stirring well. A 10% emulsion of the pesticidal composition was obtained.

Example 4: Add a mixture of 921 parts of Refufu and 1 part of benzoic acid pencil, 2 parts of sodium pyridanine sulfonate (binder), add 96 parts of clay (filler), and stir and mix thoroughly in a stirrer. .

Then, water was added in an amount of 10% of these mixtures, and the mixture was further stirred and mixed, and the mixture was granulated in a granulator, followed by ventilation drying to obtain 2% granules of the mite control composition of the present invention.

Example 5 0.1 part of resmethrin, 03 parts of benzyl benzoate, 7 parts of Kinrole, and 76 parts of deodorized kerosene are mixed and dissolved.

Fill this into an aerosol volume of 8K and remove the valve part ('
: After 1 digit, liquefied petroleum gas 85
An aerosol preparation of the mite control composition of the present invention was obtained by filling the sample under pressure.

Actual case 6 9 flf 02 parts and 0.3 flf benzyl benzoate
The mixture of li is dissolved in white kerosene and the total amount is 100 parts to obtain a 4% oil solution of the mite control composition of the present invention.

Example 7 5 g of the oil shown in Example 5 and N-(
2-Ethylhexyl)-Hisik C1-C2゜2,1)
- 5 g of 5-hebutene-2,3-7 carboximide was diluted and mixed with 11-hexane, and a non-woven fabric [made of polyethylene-cotton (3:1 weight ratio), thickness 300μ, area 11
2'), the mixture was impregnated to a weight of 30 g and dried to obtain a sheet-shaped mite control composition of the present invention.

(that's all) Special r1 applicant Earth Pharmaceutical Co., Ltd. 75

Claims (1)

[Claims] A mite control composition comprising resmethrin (including isomers) and benzoic acid pencil as juvenile components.