TW201321408A - 作為診斷標記之oxMIF - Google Patents

作為診斷標記之oxMIF Download PDF

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Publication number
TW201321408A
TW201321408A TW101137028A TW101137028A TW201321408A TW 201321408 A TW201321408 A TW 201321408A TW 101137028 A TW101137028 A TW 101137028A TW 101137028 A TW101137028 A TW 101137028A TW 201321408 A TW201321408 A TW 201321408A
Authority
TW
Taiwan
Prior art keywords
mif
oxmif
antibody
disease
antibodies
Prior art date
Application number
TW101137028A
Other languages
English (en)
Chinese (zh)
Inventor
Michael Thiele
Randolf J Kerschbaumer
Dirk Voelkel
Patrice Douillard
Friedrich Scheiflinger
Original Assignee
Baxter Healthcare Sa
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare Sa, Baxter Int filed Critical Baxter Healthcare Sa
Publication of TW201321408A publication Critical patent/TW201321408A/zh

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
TW101137028A 2011-10-07 2012-10-05 作為診斷標記之oxMIF TW201321408A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161545042P 2011-10-07 2011-10-07
US201261624943P 2012-04-16 2012-04-16
US201261668841P 2012-07-06 2012-07-06

Publications (1)

Publication Number Publication Date
TW201321408A true TW201321408A (zh) 2013-06-01

Family

ID=46980957

Family Applications (1)

Application Number Title Priority Date Filing Date
TW101137028A TW201321408A (zh) 2011-10-07 2012-10-05 作為診斷標記之oxMIF

Country Status (8)

Country Link
US (1) US9958456B2 (enExample)
EP (1) EP2748613B1 (enExample)
JP (1) JP2014530360A (enExample)
AR (1) AR088244A1 (enExample)
AU (1) AU2012320597C1 (enExample)
HK (1) HK1198591A1 (enExample)
TW (1) TW201321408A (enExample)
WO (1) WO2013050453A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106255884A (zh) * 2013-10-04 2016-12-21 赛尔爱迪尔私人有限公司 用于细胞治疗的生物标志物

Families Citing this family (9)

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WO2013050453A1 (en) 2011-10-07 2013-04-11 Baxter Healthcare S.A. Oxmif as a diagnostic marker
AU2013202693B2 (en) * 2012-04-16 2015-01-22 Baxalta GmbH Combination Therapy of Anti-MIF Antibodies and Chemotherapeutics
KR20150029017A (ko) * 2012-07-10 2015-03-17 박스터 헬쓰케어 에스에이 항-mif 면역조직화학
US9536304B2 (en) * 2013-08-30 2017-01-03 Dairy Quality Inc. Determining pathogens based on an image of somatic cells in a fluid sample
AU2015206178A1 (en) * 2014-01-03 2016-07-07 Baxalta GmbH Anti-MIF immunohistochemistry
WO2016026956A1 (en) * 2014-08-22 2016-02-25 Baxalta GmbH Detection of cho-mif contaminations
JP2021526820A (ja) * 2018-06-07 2021-10-11 オンコワン・リサーチ・アンド・ディベロップメント・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 癌治療のための抗oxMIF/抗CD3抗体
CN115943160A (zh) * 2019-12-06 2023-04-07 翁科奥内研发有限责任公司 抗oxMIF/抗CD3双特异性抗体构建体
WO2022167474A1 (en) * 2021-02-03 2022-08-11 Oncoone Research & Development Gmbh ANTI-oxMIF RADIOIMMUNOCONJUGATE

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106255884A (zh) * 2013-10-04 2016-12-21 赛尔爱迪尔私人有限公司 用于细胞治疗的生物标志物
CN106255884B (zh) * 2013-10-04 2019-01-11 赛尔爱迪尔私人有限公司 用于细胞治疗的生物标志物

Also Published As

Publication number Publication date
EP2748613A1 (en) 2014-07-02
AU2012320597A1 (en) 2013-05-09
EP2748613B1 (en) 2021-05-05
JP2014530360A (ja) 2014-11-17
HK1198591A1 (en) 2015-04-30
AU2012320597C1 (en) 2015-10-15
AU2012320597B2 (en) 2015-05-21
US9958456B2 (en) 2018-05-01
US20140248638A1 (en) 2014-09-04
WO2013050453A4 (en) 2013-06-06
WO2013050453A1 (en) 2013-04-11
AR088244A1 (es) 2014-05-21

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