TW201247627A - Novel bicyclic nitrogen containing heteroaryl TGR5 receptor modulators - Google Patents

Novel bicyclic nitrogen containing heteroaryl TGR5 receptor modulators Download PDF

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Publication number
TW201247627A
TW201247627A TW101115262A TW101115262A TW201247627A TW 201247627 A TW201247627 A TW 201247627A TW 101115262 A TW101115262 A TW 101115262A TW 101115262 A TW101115262 A TW 101115262A TW 201247627 A TW201247627 A TW 201247627A
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Taiwan
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alkyl
group
aryl
cycloalkyl
hydrogen
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TW101115262A
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English (en)
Chinese (zh)
Inventor
Jeffrey A Robl
Lawrence J Kennedy
Steven J Walker
Jun Li
Haixia Wang
William N Washburn
Saleem Ahmad
Khehyong Ngu
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Bristol Myers Squibb Co
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Publication of TW201247627A publication Critical patent/TW201247627A/zh

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    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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TW101115262A 2011-04-28 2012-04-27 Novel bicyclic nitrogen containing heteroaryl TGR5 receptor modulators TW201247627A (en)

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US20140080788A1 (en) 2014-03-20
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US9062028B2 (en) 2015-06-23
CN103619817A (zh) 2014-03-05
JP2014518853A (ja) 2014-08-07

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