TW201130977A - Mesenchymal stem cells (MSCs) isolated from mobilized peripheral blood - Google Patents

Mesenchymal stem cells (MSCs) isolated from mobilized peripheral blood Download PDF

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Publication number
TW201130977A
TW201130977A TW099142522A TW99142522A TW201130977A TW 201130977 A TW201130977 A TW 201130977A TW 099142522 A TW099142522 A TW 099142522A TW 99142522 A TW99142522 A TW 99142522A TW 201130977 A TW201130977 A TW 201130977A
Authority
TW
Taiwan
Prior art keywords
peripheral blood
individual
csf
cells
msc
Prior art date
Application number
TW099142522A
Other languages
English (en)
Chinese (zh)
Inventor
Wayne Marasco
Satish Medicetty
Yajuan Jiang
Original Assignee
Neostem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neostem Inc filed Critical Neostem Inc
Priority to TW099142522A priority Critical patent/TW201130977A/zh
Publication of TW201130977A publication Critical patent/TW201130977A/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TW099142522A 2009-12-04 2010-12-06 Mesenchymal stem cells (MSCs) isolated from mobilized peripheral blood TW201130977A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW099142522A TW201130977A (en) 2009-12-04 2010-12-06 Mesenchymal stem cells (MSCs) isolated from mobilized peripheral blood

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26682509P 2009-12-04 2009-12-04
TW99104520 2010-02-10
PCT/US2010/058980 WO2011069121A1 (fr) 2009-12-04 2010-12-03 Cellules souches mésenchymateuses (csm) isolées dans le sang périphérique mobilisé
TW099142522A TW201130977A (en) 2009-12-04 2010-12-06 Mesenchymal stem cells (MSCs) isolated from mobilized peripheral blood

Publications (1)

Publication Number Publication Date
TW201130977A true TW201130977A (en) 2011-09-16

Family

ID=44115330

Family Applications (1)

Application Number Title Priority Date Filing Date
TW099142522A TW201130977A (en) 2009-12-04 2010-12-06 Mesenchymal stem cells (MSCs) isolated from mobilized peripheral blood

Country Status (2)

Country Link
TW (1) TW201130977A (fr)
WO (1) WO2011069121A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110402286A (zh) * 2017-11-28 2019-11-01 熊仲川 自周边血液制备间质干细胞群的方法及其用途

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102864123B (zh) * 2011-07-06 2015-04-22 北京大学第三医院 一种外周血间充质干细胞的获得方法及其应用
EP2773746A4 (fr) * 2011-11-01 2015-08-05 Neostem Inc Compositions de cellules souches mésenchymateuses adultes (msc) et procédés de préparation associés
US20130244948A1 (en) * 2012-03-15 2013-09-19 Scharp Technologies, Inc. Compositions of cells, media, and methods thereof
US20160022743A1 (en) * 2012-05-31 2016-01-28 The Schepens Eye Research Institute, Inc. Human very small embryonic-like (vsel) stem cells for treatment of ocular disease
BE1020480A5 (nl) * 2012-10-01 2013-11-05 Global Stem Cell Technology Werkwijze voor de isolatie van mesenchymale stamcellen uit bloed van zoogdieren, en gebruik ervan.
CA3206342A1 (fr) 2013-05-09 2014-11-13 Advanced Neuroregenerative Therapies, Llc Facteur de croissance hematopoietique g-csf destine a etre utilise dans le traitement ou la prevention d'un dysfonctionnement lie a l'age ou d'une maladie immunitaire et de la senescence cellulaire
US20180142211A1 (en) * 2015-05-20 2018-05-24 Biokine Therapeutics Ltd Methods of mesenchymal stem cell mobilization and expansion
EP3943098A3 (fr) 2015-07-16 2022-05-11 Biokine Therapeutics Ltd. Compositions et procédés pour le traitement du cancer
KR102033920B1 (ko) 2016-02-23 2019-10-18 바이오라인알엑스 리미티드 급성 골수성 백혈병을 치료하는 방법
EP3439610A4 (fr) * 2016-04-06 2019-12-18 University of Florida Research Foundation, Inc. Utilisation thérapeutique de cellules souches mésenchymateuses induites par électroacupuncture
EP3439674A4 (fr) * 2016-04-07 2019-11-27 Dragonfly Foundation For Research & Development Corp Méthode et système permettant de réparer un tissu endommagé à l'aide de particules de plasma nucléées (nuc-p2s) et de cellules souches mésodermiques (mesosc)
WO2018187469A1 (fr) * 2017-04-05 2018-10-11 Senlin Li Méthodes et compositions pour la transplantation de cellules souches non cytotoxiques
TR201911506A2 (tr) * 2019-07-30 2021-02-22 T C Erciyes Ueniversitesi Trombosi̇tten zengi̇n fi̇bri̇n kaynakli mezenki̇mal kök hücreler
CN111671896B (zh) * 2020-07-31 2020-12-15 深圳迈吉赛尔生物科技有限公司 骨髓间充质干细胞和单克隆抗体联合治疗癌症的用途
IT202000030692A1 (it) * 2020-12-14 2022-06-14 Centro Di Riferimento Oncologico Metodo per produrre cellule mesenchimali stromali staminali modificate con proprietà migliorate, cellule modificate ottenute con tale metodo, composizione che comprende tali cellule e loro uso.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7015037B1 (en) * 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
AUPR703601A0 (en) * 2001-08-15 2001-09-06 Peter Maccallum Cancer Institute, The Identification and isolation of somatic stem cells and uses thereof
US20090004661A1 (en) * 2003-05-26 2009-01-01 Reliance Life Sciences Pvt Ltd. Method of growing mesenchymal stem cells from bone marrow
EP2489728A1 (fr) * 2006-06-15 2012-08-22 Neostem, Inc Procédure de traitement de cellules souches du sang périphérique

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110402286A (zh) * 2017-11-28 2019-11-01 熊仲川 自周边血液制备间质干细胞群的方法及其用途
CN110402286B (zh) * 2017-11-28 2023-05-26 熊仲川 自周边血液制备间质干细胞群的方法及其用途

Also Published As

Publication number Publication date
WO2011069121A1 (fr) 2011-06-09

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