TW201018477A

TW201018477A - Hepatitis C virus inhibitors

Hepatitis C virus inhibitors Download PDF

Info

Publication number: TW201018477A
Authority: TW; Taiwan
Prior art keywords: group; mmol; solvent; alkyl; water
Prior art date: 2008-09-29

Application number

TW098132584A

Other languages

English (en)

Chinese (zh)

Inventor

Sheldon Hiebert

Ramkumar Rajamani

Michael S Bowsher

Rong-Ti Li

Paul Michael Scola

Original Assignee

Bristol Myers Squibb Co

Priority date

2008-09-29

Filing date

2009-09-25

Publication date

2010-05-16

2009-09-25 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2010-05-16 Publication of TW201018477A publication Critical patent/TW201018477A/zh

Links

241000711549 Hepacivirus C Species 0.000 title abstract description 71
239000003112 inhibitor Substances 0.000 title abstract description 20
150000001875 compounds Chemical class 0.000 claims abstract description 161
239000000203 mixture Substances 0.000 claims abstract description 58
125000000217 alkyl group Chemical group 0.000 claims description 108
-1 dentate Chemical group 0.000 claims description 75
150000003839 salts Chemical class 0.000 claims description 74
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125000000623 heterocyclic group Chemical group 0.000 claims description 30
239000001257 hydrogen Substances 0.000 claims description 30
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230000000694 effects Effects 0.000 claims description 25
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125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 14
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