TW200908987A - RNA antagonist compounds for the modulation of HER3 - Google Patents
RNA antagonist compounds for the modulation of HER3 Download PDFInfo
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Applications Claiming Priority (2)
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|---|---|---|---|
| US91739207P | 2007-05-11 | 2007-05-11 | |
| US2325008P | 2008-01-24 | 2008-01-24 |
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| TW200908987A true TW200908987A (en) | 2009-03-01 |
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| TW097117351A TW200908987A (en) | 2007-05-11 | 2008-05-09 | RNA antagonist compounds for the modulation of HER3 |
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|---|---|
| US (2) | US8268793B2 (enExample) |
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| JP5564266B2 (ja) | 2007-02-16 | 2014-07-30 | メリマック ファーマシューティカルズ インコーポレーティッド | Ｅｒｂｂ３に対する抗体およびその使用 |
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| AR076053A1 (es) * | 2009-04-14 | 2011-05-18 | Schering Corp | Derivados de pirazolo[1,5-a]pirimidina como inhibidores de mtor |
| EP2544680B1 (en) | 2010-03-11 | 2015-01-14 | Merrimack Pharmaceuticals, Inc. | Use of erbb3 inhibitors in the treatment of triple negative breast cancer |
| EP2638163B1 (en) | 2010-11-12 | 2017-05-17 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| MX2013010379A (es) | 2011-03-11 | 2014-03-27 | Merrimack Pharmaceuticals Inc | Uso de inhibidores de receptores de la familia egfr en el tratamiento de canceres de mama refractarios a hormonas. |
| AU2012229062A1 (en) | 2011-03-15 | 2013-04-11 | Merrimack Pharmaceuticals, Inc. | Overcoming resistance to ErbB pathway inhibitors |
| AU2013262709A1 (en) | 2012-05-16 | 2015-01-22 | Rana Therapeutics, Inc. | Compositions and methods for modulating MECP2 expression |
| KR102028784B1 (ko) | 2012-05-16 | 2019-10-04 | 트랜슬레이트 바이오 인코포레이티드 | 유전자 발현을 조절하기 위한 조성물 및 방법 |
| US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
| EP2978845B8 (en) | 2013-03-27 | 2020-06-17 | ISARNA Therapeutics GmbH | Modified tgf-beta oligonucleotides |
| WO2015100459A2 (en) | 2013-12-27 | 2015-07-02 | Merrimack Pharmaceuticals, Inc. | Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies |
| WO2016070060A1 (en) | 2014-10-30 | 2016-05-06 | The General Hospital Corporation | Methods for modulating atrx-dependent gene repression |
| EP3271460A4 (en) | 2015-03-17 | 2019-03-13 | The General Hospital Corporation | RNA INTERACTOM OF POLYCOMB REPRESSIVE COMPLEX 1 (PRC1) |
| US10184006B2 (en) | 2015-06-04 | 2019-01-22 | Merrimack Pharmaceuticals, Inc. | Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors |
| CN116492365A (zh) * | 2022-01-19 | 2023-07-28 | 圣诺生物医药技术(广州)有限公司 | 抑制HER2和HER3的siRNA药物组合物 |
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| US4914210A (en) | 1987-10-02 | 1990-04-03 | Cetus Corporation | Oligonucleotide functionalizing reagents |
| US4962029A (en) | 1987-10-02 | 1990-10-09 | Cetus Corporation | Covalent oligonucleotide-horseradish peroxidase conjugate |
| US20030206887A1 (en) * | 1992-05-14 | 2003-11-06 | David Morrissey | RNA interference mediated inhibition of hepatitis B virus (HBV) using short interfering nucleic acid (siNA) |
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| WO1999034016A2 (en) | 1997-12-29 | 1999-07-08 | Genena Ltd. | A method for identifying and characterizing cells and tissues |
| WO2002081628A2 (en) * | 2001-04-05 | 2002-10-17 | Ribozyme Pharmaceuticals, Incorporated | Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies |
| US6277640B1 (en) | 2000-07-31 | 2001-08-21 | Isis Pharmaceuticals, Inc. | Antisense modulation of Her-3 expression |
| US20050176024A1 (en) | 2001-05-18 | 2005-08-11 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of epidermal growth factor receptor (EGFR) gene expression using short interfering nucleic acid (siNA) |
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| US20100112687A1 (en) | 2007-03-02 | 2010-05-06 | Mdrna, Inc. | Nucleic acid compounds for inhibiting erbb family gene expression and uses thereof |
| US20110286997A1 (en) | 2007-03-13 | 2011-11-24 | Hakon Hakonarson | Genetic Alterations on Chromosome 16 and Methods of Use Thereof for the Diagnosis and Treatment of Type 1 Diabetes |
| AU2008250033A1 (en) | 2007-05-11 | 2008-11-20 | Enzon Pharmaceuticals, Inc. | RNA antagonist compounds for the modulation of HER3 |
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2008
- 2008-05-09 AU AU2008250033A patent/AU2008250033A1/en not_active Abandoned
- 2008-05-09 MX MX2009012271A patent/MX2009012271A/es active IP Right Grant
- 2008-05-09 US US12/118,271 patent/US8268793B2/en not_active Expired - Fee Related
- 2008-05-09 TW TW097117351A patent/TW200908987A/zh unknown
- 2008-05-09 BR BRPI0811156A patent/BRPI0811156A2/pt not_active IP Right Cessation
- 2008-05-09 KR KR1020097025807A patent/KR20100024410A/ko not_active Ceased
- 2008-05-09 JP JP2010506953A patent/JP2010526797A/ja active Pending
- 2008-05-09 EA EA200971049A patent/EA200971049A1/ru unknown
- 2008-05-09 EP EP08759503A patent/EP2155877A2/en not_active Withdrawn
- 2008-05-09 NZ NZ581201A patent/NZ581201A/en not_active IP Right Cessation
- 2008-05-09 CA CA002686908A patent/CA2686908A1/en not_active Abandoned
- 2008-05-09 WO PCT/EP2008/055779 patent/WO2008138904A2/en not_active Ceased
- 2008-05-09 CN CN200880024089A patent/CN101849007A/zh active Pending
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2009
- 2009-11-10 IL IL202038A patent/IL202038A0/en unknown
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2012
- 2012-06-22 US US13/531,307 patent/US20120295955A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101849007A (zh) | 2010-09-29 |
| KR20100024410A (ko) | 2010-03-05 |
| NZ581201A (en) | 2012-05-25 |
| CA2686908A1 (en) | 2008-11-20 |
| EP2155877A2 (en) | 2010-02-24 |
| WO2008138904A3 (en) | 2009-04-09 |
| MX2009012271A (es) | 2010-02-04 |
| WO2008138904A2 (en) | 2008-11-20 |
| AU2008250033A1 (en) | 2008-11-20 |
| JP2010526797A (ja) | 2010-08-05 |
| IL202038A0 (en) | 2011-08-01 |
| US8268793B2 (en) | 2012-09-18 |
| EA200971049A1 (ru) | 2010-04-30 |
| BRPI0811156A2 (pt) | 2019-09-24 |
| US20080318894A1 (en) | 2008-12-25 |
| US20120295955A1 (en) | 2012-11-22 |
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