TW200902510A - Regio-specific synthesis of 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid - Google Patents

Regio-specific synthesis of 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid Download PDF

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Publication number
TW200902510A
TW200902510A TW97109960A TW97109960A TW200902510A TW 200902510 A TW200902510 A TW 200902510A TW 97109960 A TW97109960 A TW 97109960A TW 97109960 A TW97109960 A TW 97109960A TW 200902510 A TW200902510 A TW 200902510A
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TW
Taiwan
Prior art keywords
methyl
thiophene
reaction
carboxylic acid
propoxy
Prior art date
Application number
TW97109960A
Other languages
English (en)
Chinese (zh)
Inventor
Gregory G Kubiak
David J Lythgoe
Yong Yu
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of TW200902510A publication Critical patent/TW200902510A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
TW97109960A 2007-03-21 2008-03-21 Regio-specific synthesis of 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid TW200902510A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89610907P 2007-03-21 2007-03-21

Publications (1)

Publication Number Publication Date
TW200902510A true TW200902510A (en) 2009-01-16

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ID=39639204

Family Applications (1)

Application Number Title Priority Date Filing Date
TW97109960A TW200902510A (en) 2007-03-21 2008-03-21 Regio-specific synthesis of 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid

Country Status (3)

Country Link
AR (1) AR065793A1 (fr)
TW (1) TW200902510A (fr)
WO (1) WO2008115912A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105793267B (zh) 2013-10-07 2018-02-06 拜耳制药股份公司 环状噻吩并尿嘧啶甲酰胺类及其用途
CN105085469B (zh) * 2015-09-11 2017-07-11 沧州那瑞化学科技有限公司 一种5‑氯噻吩‑2‑羧酸的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP2005000039A (es) * 2004-03-26 2005-10-31 Aventis Pharma Inc Hidrocloruro de [4-(5-aminometil-2-fluoro-fenil)- piperidin-1-il]-(4-bomo-3-metil-5-propoxi-tiofen-2-il)-metanona como un inhibidor de la triptasa de mastocitos

Also Published As

Publication number Publication date
AR065793A1 (es) 2009-07-01
WO2008115912A1 (fr) 2008-09-25

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