TW200741003A - Modulation of peroxisome proliferator-activated receptors - Google Patents

Modulation of peroxisome proliferator-activated receptors

Info

Publication number
TW200741003A
TW200741003A TW095129257A TW95129257A TW200741003A TW 200741003 A TW200741003 A TW 200741003A TW 095129257 A TW095129257 A TW 095129257A TW 95129257 A TW95129257 A TW 95129257A TW 200741003 A TW200741003 A TW 200741003A
Authority
TW
Taiwan
Prior art keywords
activated receptors
modulation
peroxisome proliferator
reductase
administering
Prior art date
Application number
TW095129257A
Other languages
English (en)
Inventor
Rong-Hwa Lin
Lee-Ming Chuang
Original Assignee
Abgenomics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abgenomics Corp filed Critical Abgenomics Corp
Publication of TW200741003A publication Critical patent/TW200741003A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
TW095129257A 2005-08-12 2006-08-09 Modulation of peroxisome proliferator-activated receptors TW200741003A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70789705P 2005-08-12 2005-08-12

Publications (1)

Publication Number Publication Date
TW200741003A true TW200741003A (en) 2007-11-01

Family

ID=37737230

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095129257A TW200741003A (en) 2005-08-12 2006-08-09 Modulation of peroxisome proliferator-activated receptors

Country Status (16)

Country Link
US (1) US20070037193A1 (zh)
EP (1) EP1803809A3 (zh)
JP (1) JP2007061093A (zh)
KR (1) KR20080014936A (zh)
CN (1) CN1916167A (zh)
AR (1) AR054909A1 (zh)
AU (1) AU2006203479A1 (zh)
BR (1) BRPI0603206A (zh)
CA (1) CA2553115A1 (zh)
CO (1) CO5780135A1 (zh)
IL (1) IL177407A0 (zh)
MX (1) MXPA06009161A (zh)
NO (1) NO20063652L (zh)
SG (1) SG130141A1 (zh)
TW (1) TW200741003A (zh)
ZA (1) ZA200606661B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1856085B1 (en) * 2005-03-11 2015-07-08 Howard Florey Institute Pty Ltd Flavonoid compounds and uses thereof
WO2009026657A1 (en) * 2007-08-29 2009-03-05 The University Of Sydney Flavonoid ppar agonists
AU2009259543B2 (en) * 2008-05-28 2015-09-03 Basf Se Means and methods for assessing increased peroxisomal proliferation
JP2012513471A (ja) * 2008-12-22 2012-06-14 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ アルツハイマー病および癌の治療のためのクマリン系化合物
EP2389459B1 (en) * 2009-01-21 2014-03-26 George Atanasoff Methods and systems for control of a surface modification process
EA015364B1 (ru) * 2009-03-18 2011-06-30 Учреждение Российской Академии Наук Институт Элементоорганических Соединений Им. А.Н. Несмеянова Ран (Инэос Ран) 6,6'-диизопропил-8,8'-диметил-2,2'-динитро-3,3'-бис(трифторметил)- 3н,3'н-[9,9']ди[бензо(f)хроменил]-5,10,5',10'-тетраол, обладающий противоопухолевой и противогрибковой активностью, и способ его получения
US9752191B2 (en) * 2009-07-09 2017-09-05 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
CN101948458B (zh) * 2010-09-07 2012-11-07 中国药科大学 具有抗肿瘤活性的黄芩素衍生物及在医药上的应用
CN102964322A (zh) * 2012-12-12 2013-03-13 中国药科大学 异黄酮或类黄酮脂肪醚类衍生物、其制备方法和医药用途
JP7029777B2 (ja) * 2016-03-28 2022-03-04 国立大学法人金沢大学 アンドロゲン依存性又は非依存性前立腺癌細胞の抑制用の組成物及びそれを含有する前立腺癌の医薬製剤
CN107496414A (zh) * 2017-09-21 2017-12-22 上海华堇生物技术有限责任公司 柽柳黄素的药物用途
CN112645922B (zh) * 2020-12-24 2022-01-07 中国人民解放军空军军医大学 香豆素类化合物、制备方法及应用
CN115894422A (zh) * 2022-12-26 2023-04-04 上海中医药大学 PPARγ激动剂及其组合和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2543550B1 (fr) * 1983-04-01 1985-08-09 Cortial Nouveaux derives de la tetrahydroxy-3', 4',5,7 flavone, leur methode de preparation et leur emploi therapeutique
US4587260A (en) * 1984-06-21 1986-05-06 Warner-Lambert Company Dibenzalacetone and benzylcinnamate as non-steroidal anti-inflammatory compounds and compositions thereof
EP0455448B1 (en) * 1990-05-01 1998-12-09 R-Tech Ueno Ltd. Treatment of pancreatic disease with 15-keto-prostaglandin E compounds
CA2046069C (en) * 1990-07-10 2002-04-09 Ryuji Ueno Treatment of inflammatory diseases with 15-keto-prostaglandin compounds
AU7718796A (en) * 1995-11-17 1997-06-11 Pharmacia & Upjohn Company 4-hydroxycoumarin-3-carboxamides for the treatment of diabetes mellitus
JP2003517288A (ja) * 1999-05-20 2003-05-27 インサイト・ゲノミックス・インコーポレイテッド オキシドレダクターゼタンパク質
CN1443070A (zh) * 2000-03-24 2003-09-17 苏坎波公司 包含15－酮基－前列腺素或其衍生物的编程性细胞死亡抑制组合物
EP1402026A2 (en) * 2000-04-18 2004-03-31 Millennium Pharmaceuticals, Inc. 39228, a human alcohol dehydrogenase and uses therefor
WO2001080855A1 (en) * 2000-04-27 2001-11-01 Geron Corporation Telomerase inhibitors and methods of their use
US7326734B2 (en) * 2003-04-01 2008-02-05 The Regents Of The University Of California Treatment of bladder and urinary tract cancers

Also Published As

Publication number Publication date
SG130141A1 (en) 2007-03-20
CO5780135A1 (es) 2007-07-31
IL177407A0 (en) 2006-12-31
BRPI0603206A (pt) 2007-05-15
EP1803809A2 (en) 2007-07-04
ZA200606661B (en) 2008-05-28
AU2006203479A1 (en) 2007-03-01
EP1803809A3 (en) 2007-12-19
AR054909A1 (es) 2007-07-25
CA2553115A1 (en) 2007-02-12
MXPA06009161A (es) 2007-03-21
NO20063652L (no) 2007-02-13
CN1916167A (zh) 2007-02-21
US20070037193A1 (en) 2007-02-15
JP2007061093A (ja) 2007-03-15
KR20080014936A (ko) 2008-02-15

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