TW200733961A - Diaryl urea for treating pulmonary hypertension - Google Patents
Diaryl urea for treating pulmonary hypertensionInfo
- Publication number
- TW200733961A TW200733961A TW095141431A TW95141431A TW200733961A TW 200733961 A TW200733961 A TW 200733961A TW 095141431 A TW095141431 A TW 095141431A TW 95141431 A TW95141431 A TW 95141431A TW 200733961 A TW200733961 A TW 200733961A
- Authority
- TW
- Taiwan
- Prior art keywords
- pulmonary hypertension
- treating pulmonary
- diaryl urea
- treating
- diaryl
- Prior art date
Links
- 208000002815 pulmonary hypertension Diseases 0.000 title abstract 2
- -1 Diaryl urea Chemical compound 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- FNHKPVJBJVTLMP-UHFFFAOYSA-N regorafenib Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=C(F)C(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 FNHKPVJBJVTLMP-UHFFFAOYSA-N 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05024509 | 2005-11-10 | ||
| EP05027450 | 2005-12-15 | ||
| EP06012234 | 2006-06-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200733961A true TW200733961A (en) | 2007-09-16 |
Family
ID=37622057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095141431A TW200733961A (en) | 2005-11-10 | 2006-11-09 | Diaryl urea for treating pulmonary hypertension |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20100035888A1 (enExample) |
| EP (1) | EP1948170A1 (enExample) |
| JP (1) | JP5084736B2 (enExample) |
| KR (1) | KR20080067000A (enExample) |
| AR (1) | AR057849A1 (enExample) |
| AU (1) | AU2006312714A1 (enExample) |
| BR (1) | BRPI0618522A2 (enExample) |
| CA (1) | CA2628849A1 (enExample) |
| CR (1) | CR9953A (enExample) |
| EC (1) | ECSP088430A (enExample) |
| GT (1) | GT200800058A (enExample) |
| IL (1) | IL191178A0 (enExample) |
| NO (1) | NO20082498L (enExample) |
| PE (1) | PE20070806A1 (enExample) |
| SV (1) | SV2009002900A (enExample) |
| TW (1) | TW200733961A (enExample) |
| UY (1) | UY29903A1 (enExample) |
| WO (1) | WO2007054216A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2359244C (en) * | 1999-01-13 | 2013-10-08 | Bayer Healthcare Llc | .omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| US7371763B2 (en) * | 2001-04-20 | 2008-05-13 | Bayer Pharmaceuticals Corporation | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas |
| US20080108672A1 (en) * | 2002-01-11 | 2008-05-08 | Bernd Riedl | Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors |
| EP2324825A1 (en) | 2002-02-11 | 2011-05-25 | Bayer Healthcare LLC | Aryl ureas with angiogenesis inhibiting activity |
| AU2004212633B2 (en) * | 2003-02-21 | 2010-12-09 | ResMed Pty Ltd | Nasal assembly |
| UY28213A1 (es) * | 2003-02-28 | 2004-09-30 | Bayer Pharmaceuticals Corp | Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos. |
| DE602004007382T2 (de) * | 2003-05-20 | 2008-04-17 | Bayer Pharmaceuticals Corp., West Haven | Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten |
| DK1663978T3 (da) | 2003-07-23 | 2008-04-07 | Bayer Pharmaceuticals Corp | Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser |
| WO2006034797A1 (en) * | 2004-09-29 | 2006-04-06 | Bayer Healthcare Ag | Thermodynamically stable form of bay 43-9006 tosylate |
| AR062927A1 (es) * | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada |
| WO2008089389A2 (en) * | 2007-01-19 | 2008-07-24 | Bayer Healthcare Llc | Treatment of cancers with acquired resistance to kit inhibitors |
| WO2009156070A1 (en) * | 2008-06-25 | 2009-12-30 | Bayer Schering Pharma Aktiengesellschaft | Diaryl urea for treating heart failure |
| WO2011130728A1 (en) * | 2010-04-17 | 2011-10-20 | Bayer Healthcare Llc | Synthetic metabolites of fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention diseases and conditions |
| EP2621486A1 (en) | 2010-10-01 | 2013-08-07 | Bayer Intellectual Property GmbH | Substituted n-(2-arylamino)aryl sulfonamide-containing combinations |
| GB2503181A (en) * | 2011-03-14 | 2013-12-18 | Cellworks Res India Private Ltd | Compositions, process of preparation of said compositions and method of treating inflammatory diseases |
| EP3082428A4 (en) | 2013-12-09 | 2017-08-02 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2324825A1 (en) * | 2002-02-11 | 2011-05-25 | Bayer Healthcare LLC | Aryl ureas with angiogenesis inhibiting activity |
| ES2303585T3 (es) * | 2002-04-10 | 2008-08-16 | Virginia Commonwealth University | Combinacion de glivec(sti571) con un inhibidor de quinasa dependiente de ciclina, especialmente flavopiridol en el tratamiento de cancer. |
| DE602004007382T2 (de) * | 2003-05-20 | 2008-04-17 | Bayer Pharmaceuticals Corp., West Haven | Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten |
| DK1663978T3 (da) * | 2003-07-23 | 2008-04-07 | Bayer Pharmaceuticals Corp | Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser |
| EP1850852A4 (en) * | 2005-02-22 | 2009-11-18 | Cedars Sinai Medical Center | USE OF SILDENAFIL, VARDENAFIL AND OTHER 5-PHOSPHODIESTERASE INHIBITORS TO INCREASE THE PERMEABILITY OF THE ABNORMAL BLOOD-BRAIN DISEASE |
-
2006
- 2006-10-30 KR KR1020087013800A patent/KR20080067000A/ko not_active Withdrawn
- 2006-10-30 EP EP06818314A patent/EP1948170A1/en not_active Withdrawn
- 2006-10-30 US US12/084,662 patent/US20100035888A1/en not_active Abandoned
- 2006-10-30 AU AU2006312714A patent/AU2006312714A1/en not_active Abandoned
- 2006-10-30 BR BRPI0618522-3A patent/BRPI0618522A2/pt not_active IP Right Cessation
- 2006-10-30 CA CA002628849A patent/CA2628849A1/en not_active Abandoned
- 2006-10-30 WO PCT/EP2006/010406 patent/WO2007054216A1/en not_active Ceased
- 2006-10-30 JP JP2008539299A patent/JP5084736B2/ja not_active Expired - Fee Related
- 2006-10-31 AR ARP060104767A patent/AR057849A1/es not_active Application Discontinuation
- 2006-11-07 UY UY29903A patent/UY29903A1/es not_active Application Discontinuation
- 2006-11-09 PE PE2006001406A patent/PE20070806A1/es not_active Application Discontinuation
- 2006-11-09 TW TW095141431A patent/TW200733961A/zh unknown
-
2008
- 2008-05-01 IL IL191178A patent/IL191178A0/en unknown
- 2008-05-06 GT GT200800058A patent/GT200800058A/es unknown
- 2008-05-06 SV SV2008002900A patent/SV2009002900A/es not_active Application Discontinuation
- 2008-05-06 CR CR9953A patent/CR9953A/es not_active Application Discontinuation
- 2008-05-07 EC EC2008008430A patent/ECSP088430A/es unknown
- 2008-06-04 NO NO20082498A patent/NO20082498L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR057849A1 (es) | 2007-12-19 |
| WO2007054216A1 (en) | 2007-05-18 |
| CR9953A (es) | 2008-10-08 |
| SV2009002900A (es) | 2009-04-28 |
| AU2006312714A1 (en) | 2007-05-18 |
| IL191178A0 (en) | 2009-08-03 |
| EP1948170A1 (en) | 2008-07-30 |
| JP2009514910A (ja) | 2009-04-09 |
| PE20070806A1 (es) | 2007-09-29 |
| GT200800058A (es) | 2010-02-23 |
| ECSP088430A (es) | 2008-07-30 |
| BRPI0618522A2 (pt) | 2011-09-06 |
| UY29903A1 (es) | 2007-06-29 |
| CA2628849A1 (en) | 2007-05-18 |
| JP5084736B2 (ja) | 2012-11-28 |
| KR20080067000A (ko) | 2008-07-17 |
| US20100035888A1 (en) | 2010-02-11 |
| NO20082498L (no) | 2008-08-07 |
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