TW200511992A - Sulfonamide substituted imidazoquinolines - Google Patents
Sulfonamide substituted imidazoquinolinesInfo
- Publication number
- TW200511992A TW200511992A TW093118636A TW93118636A TW200511992A TW 200511992 A TW200511992 A TW 200511992A TW 093118636 A TW093118636 A TW 093118636A TW 93118636 A TW93118636 A TW 93118636A TW 200511992 A TW200511992 A TW 200511992A
- Authority
- TW
- Taiwan
- Prior art keywords
- sulfonamide substituted
- useful
- substituted imidazoquinolines
- compounds
- imidazoquinolines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48320003P | 2003-06-27 | 2003-06-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200511992A true TW200511992A (en) | 2005-04-01 |
Family
ID=33563911
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW093118636A TW200511992A (en) | 2003-06-27 | 2004-06-25 | Sulfonamide substituted imidazoquinolines |
TW093118635A TW200514784A (en) | 2003-06-27 | 2004-06-25 | Sulfonamide substituted imidazoquinolines |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW093118635A TW200514784A (en) | 2003-06-27 | 2004-06-25 | Sulfonamide substituted imidazoquinolines |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1638566A4 (fr) |
JP (1) | JP2007521280A (fr) |
KR (1) | KR20060035637A (fr) |
CN (1) | CN1812789B (fr) |
AR (2) | AR044922A1 (fr) |
AU (1) | AU2004253929A1 (fr) |
BR (1) | BRPI0411916A (fr) |
CA (1) | CA2529322A1 (fr) |
IL (1) | IL172427A0 (fr) |
MX (1) | MXPA06000144A (fr) |
MY (1) | MY157827A (fr) |
NZ (1) | NZ544330A (fr) |
RU (1) | RU2374246C2 (fr) |
TW (2) | TW200511992A (fr) |
WO (2) | WO2005003065A2 (fr) |
ZA (1) | ZA200600769B (fr) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
BRPI0412902A (pt) | 2003-08-12 | 2006-09-26 | 3M Innovative Properties Co | compostos contendo imidazo substituìdo por oxima |
WO2005020999A1 (fr) | 2003-08-27 | 2005-03-10 | 3M Innovative Properties Company | Imidazoquinolines substituees par aryloxy et arylalkyleneoxy |
US20050054665A1 (en) | 2003-09-05 | 2005-03-10 | 3M Innovative Properties Company | Treatment for CD5+ B cell lymphoma |
US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
ES2544477T3 (es) | 2003-10-03 | 2015-08-31 | 3M Innovative Properties Company | Imidazoquinolinas sustituidas con alcoxi |
ES2584863T3 (es) | 2003-10-03 | 2016-09-29 | 3M Innovative Properties Company | Pirazolopiridinas y análogos de las mismas |
CA2545825A1 (fr) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Composes d'un anneau d'imidazo substitue par hydroxylamine |
CN1906193A (zh) | 2003-11-14 | 2007-01-31 | 3M创新有限公司 | 肟取代的咪唑环化合物 |
NZ547467A (en) | 2003-11-25 | 2010-06-25 | 3M Innovative Properties Co | Substituted imidazo ring system and methods |
JP2007513165A (ja) * | 2003-12-02 | 2007-05-24 | スリーエム イノベイティブ プロパティズ カンパニー | Irm化合物を含む併用薬および治療方法 |
WO2005066170A1 (fr) | 2003-12-29 | 2005-07-21 | 3M Innovative Properties Company | Imidazoquinolines a substitution arylalcenyle et arylalkynyle |
JP2007517044A (ja) | 2003-12-30 | 2007-06-28 | スリーエム イノベイティブ プロパティズ カンパニー | イミダゾキノリニル、イミダゾピリジニル、およびイミダゾナフチリジニルスルホンアミド |
AU2005228150A1 (en) | 2004-03-24 | 2005-10-13 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
WO2005123080A2 (fr) | 2004-06-15 | 2005-12-29 | 3M Innovative Properties Company | Imidazoquinolines et imidazonaphthyridines substituees par un heterocyclyle contenant un azote |
US7897609B2 (en) | 2004-06-18 | 2011-03-01 | 3M Innovative Properties Company | Aryl substituted imidazonaphthyridines |
US8541438B2 (en) | 2004-06-18 | 2013-09-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
WO2006009826A1 (fr) | 2004-06-18 | 2006-01-26 | 3M Innovative Properties Company | Thiazoloquinolines et thiazolonaphtyridines substitues par aryloxy et arylalkyleneoxy |
WO2006065280A2 (fr) | 2004-06-18 | 2006-06-22 | 3M Innovative Properties Company | Composes a noyau imidazo a substitutif d'isoxazole, de dihydroisoxazole et d'oxadiazole |
US7943609B2 (en) | 2004-12-30 | 2011-05-17 | 3M Innovative Proprerties Company | Chiral fused [1,2]imidazo[4,5-C] ring compounds |
JP2008526752A (ja) * | 2004-12-30 | 2008-07-24 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答調節剤化合物の多経路投与 |
WO2006083440A2 (fr) | 2004-12-30 | 2006-08-10 | 3M Innovative Properties Company | Composes chiraux [1,2]imidazo[4,5-c] substitues a noyau fusionne |
JP2008530022A (ja) | 2005-02-04 | 2008-08-07 | コーリー ファーマシューティカル グループ,インコーポレイテッド | 免疫反応調節物質を含む水性ゲル処方物 |
US20080318998A1 (en) | 2005-02-09 | 2008-12-25 | Coley Pharmaceutical Group, Inc. | Alkyloxy Substituted Thiazoloquinolines and Thiazolonaphthyridines |
AU2006213746A1 (en) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods |
US7943610B2 (en) | 2005-04-01 | 2011-05-17 | 3M Innovative Properties Company | Pyrazolopyridine-1,4-diamines and analogs thereof |
CA2602590A1 (fr) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | Composes cycliques 1-pyrazolo[3,4-c] substitues comme modulateurs de la biosynthese de cytokine destines au traitement d'infections virales et de maladies neoplastiques |
ZA200803029B (en) * | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
JP2009507856A (ja) * | 2005-09-09 | 2009-02-26 | コーリー ファーマシューティカル グループ,インコーポレイテッド | N−{2−[4−アミノ−2−(エトキシメチル)−1H−イミダゾ[4,5−c]キノリン−1−イル]−1,1−ジメチルエチル}メタンスルホンアミドのアミドおよびカルバマート誘導体ならびに方法 |
KR20080048551A (ko) * | 2005-09-23 | 2008-06-02 | 콜레이 파마시티컬 그룹, 인코포레이티드 | 1H-이미다조[4,5-c]피리딘 및 그의 유사체의 제조법 |
US8951528B2 (en) | 2006-02-22 | 2015-02-10 | 3M Innovative Properties Company | Immune response modifier conjugates |
WO2008008432A2 (fr) | 2006-07-12 | 2008-01-17 | Coley Pharmaceutical Group, Inc. | Composés à cycle [1,2] imidazo [4,5-c] fusionné chiral substitué et procédés correspondants |
CA2719544C (fr) * | 2008-03-24 | 2018-01-09 | 4Sc Ag | Imidazoquinolines substituees |
ES2617451T3 (es) | 2010-08-17 | 2017-06-19 | 3M Innovative Properties Company | Composiciones lipidadas de compuestos modificadores de la respuesta inmunitaria, formulaciones, y métodos |
JP6460789B2 (ja) | 2011-06-03 | 2019-01-30 | スリーエム イノベイティブ プロパティズ カンパニー | ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体 |
US9107958B2 (en) | 2011-06-03 | 2015-08-18 | 3M Innovative Properties Company | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom |
US9695171B2 (en) | 2013-12-17 | 2017-07-04 | Pfizer Inc. | 3,4-disubstituted-1 H-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7H-pyrrolo[2,3-c]pyridazines as LRRK2 inhibitors |
EP3350178B1 (fr) * | 2015-09-14 | 2021-10-20 | Pfizer Inc. | Nouveaux dérivés imidazo [4,5-c]quinoline et imidazo [4,5-c][1,5]naphthyridine utilisés comme inhibiteurs de lrrk2 |
KR20230149857A (ko) | 2016-07-07 | 2023-10-27 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 항체-애쥬번트 접합체 |
KR102582626B1 (ko) | 2017-03-10 | 2023-09-22 | 화이자 인코포레이티드 | Lrrk2 억제제로서의 신규 이미다조[4,5-c]퀴놀린 유도체 |
HUE058995T2 (hu) | 2017-09-06 | 2022-10-28 | BioNTech SE | Szubsztituált imidazokinolinok mint a TLR7 agonistái |
CA3086439A1 (fr) | 2017-12-20 | 2019-06-27 | 3M Innovative Properties Company | Composes imidazo [4,5-c]quinoleine a substitution amide ayant un groupe de liaison a chaine ramifiee destines a etre utilises en tant que modificateur de la reponse immunitaire |
WO2020190725A1 (fr) | 2019-03-15 | 2020-09-24 | Bolt Biotherapeutics, Inc. | Immunoconjugués ciblant le her2 |
AU2020407871A1 (en) * | 2019-12-20 | 2022-06-30 | Nammi Therapeutics, Inc. | Formulated and/or co-formulated liposome compositions containing toll-like receptor ("TLR") agonist prodrugs useful in the treatment of cancer and methods thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6331539B1 (en) * | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
JP2005513021A (ja) * | 2001-11-16 | 2005-05-12 | スリーエム イノベイティブ プロパティズ カンパニー | Irm化合物およびトール様受容体経路に関する方法および組成物 |
US6677349B1 (en) * | 2001-12-21 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
-
2004
- 2004-06-24 MY MYPI20042461A patent/MY157827A/en unknown
- 2004-06-25 AR ARP040102247A patent/AR044922A1/es unknown
- 2004-06-25 BR BRPI0411916-9A patent/BRPI0411916A/pt not_active IP Right Cessation
- 2004-06-25 RU RU2005138915/04A patent/RU2374246C2/ru not_active IP Right Cessation
- 2004-06-25 WO PCT/US2004/020607 patent/WO2005003065A2/fr active Application Filing
- 2004-06-25 CA CA002529322A patent/CA2529322A1/fr not_active Abandoned
- 2004-06-25 WO PCT/US2004/020606 patent/WO2005003064A2/fr not_active Application Discontinuation
- 2004-06-25 TW TW093118636A patent/TW200511992A/zh unknown
- 2004-06-25 TW TW093118635A patent/TW200514784A/zh unknown
- 2004-06-25 JP JP2006517711A patent/JP2007521280A/ja active Pending
- 2004-06-25 NZ NZ544330A patent/NZ544330A/en unknown
- 2004-06-25 CN CN2004800181459A patent/CN1812789B/zh not_active Expired - Fee Related
- 2004-06-25 EP EP04756208A patent/EP1638566A4/fr not_active Withdrawn
- 2004-06-25 MX MXPA06000144A patent/MXPA06000144A/es unknown
- 2004-06-25 KR KR1020057024904A patent/KR20060035637A/ko not_active Application Discontinuation
- 2004-06-25 AR ARP040102248A patent/AR044923A1/es unknown
- 2004-06-25 AU AU2004253929A patent/AU2004253929A1/en not_active Abandoned
-
2005
- 2005-12-07 IL IL172427A patent/IL172427A0/en unknown
-
2006
- 2006-01-26 ZA ZA200600769A patent/ZA200600769B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN1812789A (zh) | 2006-08-02 |
JP2007521280A (ja) | 2007-08-02 |
CN1812789B (zh) | 2010-07-14 |
WO2005003064A2 (fr) | 2005-01-13 |
EP1638566A4 (fr) | 2009-03-25 |
MXPA06000144A (es) | 2006-04-07 |
WO2005003065A3 (fr) | 2005-03-10 |
WO2005003064A3 (fr) | 2005-03-31 |
BRPI0411916A (pt) | 2006-08-15 |
MY157827A (en) | 2016-07-29 |
RU2005138915A (ru) | 2006-06-27 |
CA2529322A1 (fr) | 2005-01-13 |
AR044923A1 (es) | 2005-10-12 |
WO2005003065A2 (fr) | 2005-01-13 |
NZ544330A (en) | 2009-06-26 |
ZA200600769B (en) | 2007-05-30 |
AU2004253929A1 (en) | 2005-01-13 |
EP1638566A2 (fr) | 2006-03-29 |
IL172427A0 (en) | 2006-04-10 |
KR20060035637A (ko) | 2006-04-26 |
TW200514784A (en) | 2005-05-01 |
RU2374246C2 (ru) | 2009-11-27 |
AR044922A1 (es) | 2005-10-12 |
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