TR200200560T2 - Vazopresin reseptör antagonistleri olarak indoloazepinler - Google Patents
Vazopresin reseptör antagonistleri olarak indoloazepinlerInfo
- Publication number
- TR200200560T2 TR200200560T2 TR2002/00560T TR200200560T TR200200560T2 TR 200200560 T2 TR200200560 T2 TR 200200560T2 TR 2002/00560 T TR2002/00560 T TR 2002/00560T TR 200200560 T TR200200560 T TR 200200560T TR 200200560 T2 TR200200560 T2 TR 200200560T2
- Authority
- TR
- Turkey
- Prior art keywords
- indoloazepines
- receptor antagonists
- vasopressin receptor
- tribiclic
- indoloazepine
- Prior art date
Links
- KDDCNSWPVMLDHI-UHFFFAOYSA-N azepino[3,2-b]indole Chemical class C1=CC=CN=C2C3=CC=CC=C3N=C21 KDDCNSWPVMLDHI-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002536 vasopressin receptor antagonist Substances 0.000 title 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Söz konusu bulus vazopresin reseptör antagonistleri olarak faydali bir sekilde kullanilan tribiklik indoloazepin terkipleri, bulusa uygun terkipleri ihtiva eden farmasötik bilesimler ve artan vasküler direnç ve kardiyak yetersizlik gibi durumlarin tedavisi ile ilgili yöntemleri kapsamaktadir.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13962899P | 1999-06-17 | 1999-06-17 | |
US09/592,520 US6765004B1 (en) | 1999-06-17 | 2000-06-12 | Indoloazepines as vasopressin receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200200560T2 true TR200200560T2 (tr) | 2003-01-21 |
Family
ID=26837417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/00560T TR200200560T2 (tr) | 1999-06-17 | 2000-06-15 | Vazopresin reseptör antagonistleri olarak indoloazepinler |
Country Status (20)
Country | Link |
---|---|
US (1) | US6765004B1 (tr) |
EP (1) | EP1214323B1 (tr) |
JP (1) | JP2003502426A (tr) |
CN (1) | CN1399638A (tr) |
AT (1) | ATE282621T1 (tr) |
AU (1) | AU774768B2 (tr) |
BR (1) | BR0012294A (tr) |
CA (1) | CA2375268A1 (tr) |
DE (1) | DE60015997T2 (tr) |
DK (1) | DK1214323T3 (tr) |
ES (1) | ES2233402T3 (tr) |
HU (1) | HUP0201725A3 (tr) |
IL (1) | IL147130A0 (tr) |
MX (1) | MXPA01013286A (tr) |
NO (1) | NO20016155L (tr) |
NZ (1) | NZ516209A (tr) |
PL (1) | PL352998A1 (tr) |
PT (1) | PT1214323E (tr) |
TR (1) | TR200200560T2 (tr) |
WO (1) | WO2000078762A1 (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0324269D0 (en) * | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
US8567448B2 (en) * | 2007-12-26 | 2013-10-29 | Smart Pipe Company, Inc. | Methods and systems for in situ pipe lining |
US8828989B2 (en) | 2011-09-26 | 2014-09-09 | Hoffmann-La Roche Inc. | Oxy-cyclohexyl-4H,6H-5-oxa-2,3,10b-triaza-benzo[E]azulenes as V1A antagonists |
CN112107568B (zh) * | 2019-06-19 | 2022-03-25 | 北京龙嘉博创医药科技有限公司 | 二芳基酰胺类化合物及其应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3314942A (en) * | 1964-08-06 | 1967-04-18 | Upjohn Co | 3, 4, 5, 6-tetrahydro-1h-azepino(4, 3, 2-cd) indoles |
US3249623A (en) * | 1964-09-24 | 1966-05-03 | Upjohn Co | Derivatives of 3, 4, 5, 6-tetrahydro-1h-azepino [4, 3, 2-cd] indoles |
BE795451A (fr) * | 1972-02-23 | 1973-08-16 | Pfizer | Agents hypoglycemiants aza indoliques tricycliques |
DE3525564A1 (de) * | 1985-07-15 | 1987-02-05 | Schering Ag | Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
JPS6434988A (en) * | 1987-07-30 | 1989-02-06 | Kissei Pharmaceutical | Azepinoindole derivative |
GB9307527D0 (en) | 1993-04-13 | 1993-06-02 | Fujisawa Pharmaceutical Co | New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
DE69434032T2 (de) * | 1993-07-21 | 2005-09-22 | Yamanouchi Pharmaceutical Co., Ltd. | Zwischenprodukt zur Herstellung von kondensierten Benzazepinderivate |
DE4438178A1 (de) * | 1994-10-26 | 1996-05-02 | Bayer Ag | N-Methyl-N-isopropyl-heteroaryloxyacetamide |
-
2000
- 2000-06-12 US US09/592,520 patent/US6765004B1/en not_active Expired - Lifetime
- 2000-06-15 NZ NZ516209A patent/NZ516209A/xx unknown
- 2000-06-15 CN CN00811602A patent/CN1399638A/zh active Pending
- 2000-06-15 PT PT00941464T patent/PT1214323E/pt unknown
- 2000-06-15 JP JP2001504928A patent/JP2003502426A/ja active Pending
- 2000-06-15 BR BR0012294-7A patent/BR0012294A/pt not_active IP Right Cessation
- 2000-06-15 HU HU0201725A patent/HUP0201725A3/hu unknown
- 2000-06-15 EP EP00941464A patent/EP1214323B1/en not_active Expired - Lifetime
- 2000-06-15 TR TR2002/00560T patent/TR200200560T2/tr unknown
- 2000-06-15 AU AU56170/00A patent/AU774768B2/en not_active Ceased
- 2000-06-15 AT AT00941464T patent/ATE282621T1/de not_active IP Right Cessation
- 2000-06-15 DK DK00941464T patent/DK1214323T3/da active
- 2000-06-15 MX MXPA01013286A patent/MXPA01013286A/es unknown
- 2000-06-15 CA CA002375268A patent/CA2375268A1/en not_active Abandoned
- 2000-06-15 PL PL00352998A patent/PL352998A1/xx unknown
- 2000-06-15 WO PCT/US2000/016549 patent/WO2000078762A1/en active IP Right Grant
- 2000-06-15 IL IL14713000A patent/IL147130A0/xx unknown
- 2000-06-15 DE DE60015997T patent/DE60015997T2/de not_active Expired - Fee Related
- 2000-06-15 ES ES00941464T patent/ES2233402T3/es not_active Expired - Lifetime
-
2001
- 2001-12-17 NO NO20016155A patent/NO20016155L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1214323A1 (en) | 2002-06-19 |
NO20016155L (no) | 2002-02-15 |
PL352998A1 (en) | 2003-09-22 |
WO2000078762A1 (en) | 2000-12-28 |
IL147130A0 (en) | 2002-08-14 |
DE60015997T2 (de) | 2005-12-01 |
NO20016155D0 (no) | 2001-12-17 |
CA2375268A1 (en) | 2000-12-28 |
PT1214323E (pt) | 2005-02-28 |
BR0012294A (pt) | 2002-07-02 |
HUP0201725A3 (en) | 2003-09-29 |
MXPA01013286A (es) | 2003-08-20 |
JP2003502426A (ja) | 2003-01-21 |
AU774768B2 (en) | 2004-07-08 |
ATE282621T1 (de) | 2004-12-15 |
DE60015997D1 (de) | 2004-12-23 |
US6765004B1 (en) | 2004-07-20 |
NZ516209A (en) | 2004-01-30 |
ES2233402T3 (es) | 2005-06-16 |
EP1214323B1 (en) | 2004-11-17 |
HUP0201725A2 (en) | 2002-10-28 |
CN1399638A (zh) | 2003-02-26 |
AU5617000A (en) | 2001-01-09 |
DK1214323T3 (da) | 2005-01-10 |
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