TR200100208T2 - Kalpte post-iskemik tahribatın azaltılması için bir yapısına glükoz almayı artırıcının kullanımı. - Google Patents

Kalpte post-iskemik tahribatın azaltılması için bir yapısına glükoz almayı artırıcının kullanımı.

Info

Publication number
TR200100208T2
TR200100208T2 TR2001/00208T TR200100208T TR200100208T2 TR 200100208 T2 TR200100208 T2 TR 200100208T2 TR 2001/00208 T TR2001/00208 T TR 2001/00208T TR 200100208 T TR200100208 T TR 200100208T TR 200100208 T2 TR200100208 T2 TR 200100208T2
Authority
TR
Turkey
Prior art keywords
heart
glucose uptake
ischemic damage
reduce post
uptake promoter
Prior art date
Application number
TR2001/00208T
Other languages
English (en)
Inventor
Michel Alain Bril Antoine
Edwin Buckingham Robin
Khandoudi Nassirah
Original Assignee
Smithkline Beecham P.L.C.
Smithkline Beecham Laboratoires Pharmaceutiques S.A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9815871.0A external-priority patent/GB9815871D0/en
Priority claimed from GBGB9815872.8A external-priority patent/GB9815872D0/en
Application filed by Smithkline Beecham P.L.C., Smithkline Beecham Laboratoires Pharmaceutiques S.A.S. filed Critical Smithkline Beecham P.L.C.
Publication of TR200100208T2 publication Critical patent/TR200100208T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Kalpte post-iskemik tahribatin azaltilmasi için ve/veya miyokardiyal iskemeyi takiben kalbin islevsel olarak iyilesmesini gelistirmek için, ihtiyaci olan bir insana veya baska bir memeliye bir yapisina glükoz almayi artiricidan etkili ve toksik olmayan bir miktarda uygulanmasini içeren bir yöntem.
TR2001/00208T 1998-07-21 1999-07-21 Kalpte post-iskemik tahribatın azaltılması için bir yapısına glükoz almayı artırıcının kullanımı. TR200100208T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9815871.0A GB9815871D0 (en) 1998-07-21 1998-07-21 Novel compound
GBGB9815872.8A GB9815872D0 (en) 1998-07-21 1998-07-21 Novel method

Publications (1)

Publication Number Publication Date
TR200100208T2 true TR200100208T2 (tr) 2001-05-21

Family

ID=26314086

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00208T TR200100208T2 (tr) 1998-07-21 1999-07-21 Kalpte post-iskemik tahribatın azaltılması için bir yapısına glükoz almayı artırıcının kullanımı.

Country Status (35)

Country Link
EP (2) EP1523980A3 (tr)
JP (1) JP2002521325A (tr)
KR (1) KR20010079550A (tr)
CN (1) CN1167416C (tr)
AP (1) AP1416A (tr)
AR (1) AR020614A1 (tr)
AT (1) ATE318588T1 (tr)
AU (1) AU5053599A (tr)
BG (1) BG105251A (tr)
BR (1) BR9912144A (tr)
CA (1) CA2338216A1 (tr)
CO (1) CO5060465A1 (tr)
CY (1) CY1106078T1 (tr)
CZ (1) CZ2001250A3 (tr)
DE (1) DE69930125T2 (tr)
DK (1) DK1098638T3 (tr)
DZ (1) DZ2854A1 (tr)
EA (1) EA004772B1 (tr)
ES (1) ES2259839T3 (tr)
GC (1) GC0000173A (tr)
HU (1) HUP0103870A3 (tr)
ID (1) ID27850A (tr)
IL (1) IL140741A0 (tr)
MA (1) MA26662A1 (tr)
NO (1) NO20010293L (tr)
NZ (1) NZ509175A (tr)
OA (1) OA11583A (tr)
PE (1) PE20000881A1 (tr)
PL (1) PL345663A1 (tr)
PT (1) PT1098638E (tr)
SI (1) SI1098638T1 (tr)
SK (1) SK1022001A3 (tr)
TR (1) TR200100208T2 (tr)
TW (2) TWI239836B (tr)
WO (1) WO2000004889A1 (tr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2204684T3 (es) * 1999-08-27 2004-05-01 Eli Lilly And Company Derivados de biaril-oxa(tia)zol y su uso como modulares de ppar.
YU1203A (sh) * 2000-06-16 2006-05-25 Smithkline Beecham P.L.C. Lečenje i prevencija stanja vezanih za insulinsku rezistenciju srca
AU2002319677B8 (en) 2001-07-23 2009-04-30 Atwater Management Llc Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842925A1 (en) * 1987-09-04 1998-05-20 Beecham Group Plc Substituted thiazolidinedione derivatives
JPH05202042A (ja) * 1992-01-24 1993-08-10 Sankyo Co Ltd 糖尿病性合併症治療剤
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
GB9611947D0 (en) * 1996-06-07 1996-08-07 Glaxo Group Ltd Medicaments
US6277819B1 (en) * 1996-08-30 2001-08-21 Eli Lilly And Company Use of GLP-1 or analogs in treatment of myocardial infarction
HUP0002941A3 (en) * 1996-09-12 2001-11-28 Sankyo Company Ltd Chuo Ku Glutathione reductase activity potentiator containing troglitazone
WO1999025346A1 (en) * 1997-11-19 1999-05-27 Takeda Chemical Industries, Ltd. Novel apoptosis inhibitors
WO1999043326A1 (en) * 1998-02-24 1999-09-02 The Trustees Of The University Of Pennsylvania Use of a cardiac purinoceptor to effect cellular glucose uptake
AU4005299A (en) * 1998-05-19 1999-12-06 Regents Of The University Of California, The Thiazolidine and oxazolidine derivatives for the treatment of acute myocardial infarction and inhibition of cardiomyocyte apoptosis
US5968960A (en) * 1999-01-14 1999-10-19 The Regents Of The University Of California Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism

Also Published As

Publication number Publication date
BG105251A (en) 2001-10-31
NO20010293D0 (no) 2001-01-18
EA200100164A1 (ru) 2001-08-27
KR20010079550A (ko) 2001-08-22
EA004772B1 (ru) 2004-08-26
DE69930125D1 (de) 2006-04-27
NO20010293L (no) 2001-03-07
SI1098638T1 (sl) 2006-06-30
EP1523980A2 (en) 2005-04-20
EP1523980A3 (en) 2009-03-18
CY1106078T1 (el) 2011-06-08
AP1416A (en) 2005-06-13
NZ509175A (en) 2003-10-31
TW200307532A (en) 2003-12-16
WO2000004889A1 (en) 2000-02-03
ID27850A (id) 2001-04-26
MA26662A1 (fr) 2004-12-20
CZ2001250A3 (cs) 2002-03-13
CN1167416C (zh) 2004-09-22
CA2338216A1 (en) 2000-02-03
BR9912144A (pt) 2001-04-03
AR020614A1 (es) 2002-05-22
AU5053599A (en) 2000-02-14
TWI239836B (en) 2005-09-21
OA11583A (en) 2004-07-01
HUP0103870A2 (hu) 2002-05-29
HUP0103870A3 (en) 2003-06-30
EP1098638A1 (en) 2001-05-16
ATE318588T1 (de) 2006-03-15
CN1310619A (zh) 2001-08-29
AP2001002033A0 (en) 2001-03-31
EP1098638B1 (en) 2006-03-01
GC0000173A (en) 2006-03-29
JP2002521325A (ja) 2002-07-16
IL140741A0 (en) 2002-02-10
SK1022001A3 (en) 2001-08-06
PL345663A1 (en) 2002-01-02
DZ2854A1 (fr) 2003-12-01
PT1098638E (pt) 2006-07-31
ES2259839T3 (es) 2006-10-16
DE69930125T2 (de) 2006-10-05
DK1098638T3 (da) 2006-06-19
CO5060465A1 (es) 2001-07-30
PE20000881A1 (es) 2000-10-07

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