TR200002543T2 - Fosfolipaz önleyici sodyum [[3-(2-amino-1,2-dioksietil-1-fenilmetil) -2-etil-1-fenilmetil)- 1H-indol-4-il]oksi] asetat içeren farmasötik kompozisyonlar - Google Patents
Fosfolipaz önleyici sodyum [[3-(2-amino-1,2-dioksietil-1-fenilmetil) -2-etil-1-fenilmetil)- 1H-indol-4-il]oksi] asetat içeren farmasötik kompozisyonlarInfo
- Publication number
- TR200002543T2 TR200002543T2 TR2000/02543T TR200002543T TR200002543T2 TR 200002543 T2 TR200002543 T2 TR 200002543T2 TR 2000/02543 T TR2000/02543 T TR 2000/02543T TR 200002543 T TR200002543 T TR 200002543T TR 200002543 T2 TR200002543 T2 TR 200002543T2
- Authority
- TR
- Turkey
- Prior art keywords
- phenylmethyl
- indol
- oxy
- acetate
- ethyl
- Prior art date
Links
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 title abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229910052708 sodium Inorganic materials 0.000 title abstract 2
- 239000011734 sodium Substances 0.000 title abstract 2
- 229940124154 Phospholipase inhibitor Drugs 0.000 title 1
- 239000003428 phospholipase inhibitor Substances 0.000 title 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 229940102223 injectable solution Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Sodyum [[3-(2-amino-1,2-dioksitil) -2-etil-1-fenilmetil)- 1H-indol-4-il]oksi]asetat, bir Çözündürücü ve Stabilizer içeren liyofilize edilmis farmasötik bir kompozisyon tarif edilmistir. Bu kompozisyonlar saklamaya uygundur ve sepsis, vb. tedavisi için enjekte edilebilir çözelti olusturmak üzere sulu bir madde içinde hemen erir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7665998P | 1998-03-03 | 1998-03-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200002543T2 true TR200002543T2 (tr) | 2000-11-21 |
Family
ID=22133426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/02543T TR200002543T2 (tr) | 1998-03-03 | 1999-03-02 | Fosfolipaz önleyici sodyum [[3-(2-amino-1,2-dioksietil-1-fenilmetil) -2-etil-1-fenilmetil)- 1H-indol-4-il]oksi] asetat içeren farmasötik kompozisyonlar |
Country Status (21)
Country | Link |
---|---|
US (1) | US6166062A (tr) |
EP (1) | EP1058547B1 (tr) |
JP (3) | JP2002505282A (tr) |
KR (1) | KR20010034552A (tr) |
CN (1) | CN1299277A (tr) |
AT (1) | ATE310513T1 (tr) |
AU (1) | AU757002B2 (tr) |
BR (1) | BR9908479A (tr) |
CA (1) | CA2322796A1 (tr) |
DE (1) | DE69928500T2 (tr) |
EA (1) | EA003864B1 (tr) |
ES (1) | ES2253877T3 (tr) |
HU (1) | HUP0102812A3 (tr) |
ID (1) | ID27487A (tr) |
IL (1) | IL138154A0 (tr) |
NO (1) | NO20004306L (tr) |
NZ (1) | NZ506578A (tr) |
PL (1) | PL342822A1 (tr) |
TR (1) | TR200002543T2 (tr) |
TW (1) | TW570795B (tr) |
WO (1) | WO1999044604A1 (tr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001236440A1 (en) * | 2000-01-25 | 2001-08-07 | Eli Lilly And Company | Method for the treatment of inflammation with spla2 inhibitors |
AU2001229252A1 (en) * | 2000-03-09 | 2001-09-17 | Eli Lilly And Company | Method for the treatment of renal dysfunction with spla2 inhibitors |
CA2413582A1 (en) * | 2000-07-14 | 2002-01-24 | Eli Lilly And Company | Use of a spla2 inhibitor for the treatment of sepsis |
TWI232102B (en) * | 2001-07-17 | 2005-05-11 | Shionogi & Co | A pharmaceutical formulation for injection |
CN1568999A (zh) * | 2003-07-14 | 2005-01-26 | 南宁枫叶药业有限公司 | 稳定的医药用河豚毒素冷冻干燥制剂 |
KR20070009671A (ko) * | 2004-05-06 | 2007-01-18 | 사이덱스 인크 | 세르트랄린 및 술포알킬 에테르 시클로덱스트린을 함유하는맛 마스킹된 제제 |
PL2029134T3 (pl) * | 2006-06-09 | 2011-12-30 | Ucb Pharma Gmbh | Stabilizowane kompozycje farmaceutyczne zawierające fezoterodynę |
PT2111124E (pt) * | 2007-02-12 | 2012-02-08 | Lassaad Boujbel | Solução estéril de sucralose sem conservantes e seu processo de preparação |
JP5174365B2 (ja) * | 2007-03-23 | 2013-04-03 | 第一三共株式会社 | キノロン含有凍結乾燥製剤の製造方法 |
EP2106788A1 (en) * | 2008-04-04 | 2009-10-07 | Ipsen Pharma | Liquid and freeze dried formulations |
NZ720946A (en) | 2009-04-29 | 2017-09-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
KR20140053952A (ko) * | 2011-08-26 | 2014-05-08 | 제이더블유중외제약 주식회사 | 피라지노-트리아진 유도체를 포함하는 조성물 |
EP2923710A1 (en) | 2014-03-27 | 2015-09-30 | Universitätsklinikum Heidelberg | Bacterial phospholipase inhibitors as modulator of colonic bacterial flora |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO873860L (no) * | 1986-10-31 | 1988-05-02 | Asta Pharma Ag | Ifosfamid-lyofilisat og fremgangsmaate til deres fremstilling. |
JPH02207092A (ja) * | 1989-02-07 | 1990-08-16 | Kirin Brewery Co Ltd | アンスラサイクリン化合物またはその塩の凍結乾燥製剤の製造法 |
US5741523A (en) * | 1993-10-27 | 1998-04-21 | Pharmacia & Upjohn Company | Stabilized prostaglandin E1 |
PT675110E (pt) * | 1994-04-01 | 2002-11-29 | Lilly Co Eli | 1h-indole-3-glioxilamidas inibidoras da spla2 |
-
1999
- 1999-03-02 JP JP2000534206A patent/JP2002505282A/ja active Pending
- 1999-03-02 NZ NZ506578A patent/NZ506578A/en unknown
- 1999-03-02 TR TR2000/02543T patent/TR200002543T2/tr unknown
- 1999-03-02 HU HU0102812A patent/HUP0102812A3/hu unknown
- 1999-03-02 CN CN99805662A patent/CN1299277A/zh active Pending
- 1999-03-02 EP EP99908612A patent/EP1058547B1/en not_active Expired - Lifetime
- 1999-03-02 ES ES99908612T patent/ES2253877T3/es not_active Expired - Lifetime
- 1999-03-02 EA EA200000897A patent/EA003864B1/ru not_active IP Right Cessation
- 1999-03-02 IL IL13815499A patent/IL138154A0/xx unknown
- 1999-03-02 KR KR1020007009726A patent/KR20010034552A/ko not_active Application Discontinuation
- 1999-03-02 AU AU27998/99A patent/AU757002B2/en not_active Ceased
- 1999-03-02 US US09/260,490 patent/US6166062A/en not_active Expired - Lifetime
- 1999-03-02 ID IDW20001981A patent/ID27487A/id unknown
- 1999-03-02 DE DE69928500T patent/DE69928500T2/de not_active Expired - Lifetime
- 1999-03-02 WO PCT/US1999/004516 patent/WO1999044604A1/en active IP Right Grant
- 1999-03-02 AT AT99908612T patent/ATE310513T1/de not_active IP Right Cessation
- 1999-03-02 BR BR9908479-1A patent/BR9908479A/pt not_active IP Right Cessation
- 1999-03-02 PL PL99342822A patent/PL342822A1/xx not_active Application Discontinuation
- 1999-03-02 CA CA002322796A patent/CA2322796A1/en not_active Abandoned
- 1999-08-27 TW TW088103212A patent/TW570795B/zh active
-
2000
- 2000-08-29 NO NO20004306A patent/NO20004306L/no not_active Application Discontinuation
-
2005
- 2005-11-16 JP JP2005330964A patent/JP2006096761A/ja not_active Withdrawn
-
2010
- 2010-11-05 JP JP2010247975A patent/JP2011021042A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ES2253877T3 (es) | 2006-06-01 |
TW570795B (en) | 2004-01-11 |
HUP0102812A3 (en) | 2002-01-28 |
KR20010034552A (ko) | 2001-04-25 |
IL138154A0 (en) | 2001-10-31 |
AU757002B2 (en) | 2003-01-30 |
HUP0102812A2 (hu) | 2001-12-28 |
EP1058547A1 (en) | 2000-12-13 |
CN1299277A (zh) | 2001-06-13 |
WO1999044604A1 (en) | 1999-09-10 |
EA003864B1 (ru) | 2003-10-30 |
AU2799899A (en) | 1999-09-20 |
NO20004306L (no) | 2000-10-10 |
CA2322796A1 (en) | 1999-09-10 |
ATE310513T1 (de) | 2005-12-15 |
PL342822A1 (en) | 2001-07-02 |
ID27487A (id) | 2001-04-12 |
EP1058547B1 (en) | 2005-11-23 |
DE69928500D1 (de) | 2005-12-29 |
JP2006096761A (ja) | 2006-04-13 |
NZ506578A (en) | 2003-09-26 |
JP2011021042A (ja) | 2011-02-03 |
DE69928500T2 (de) | 2006-08-03 |
US6166062A (en) | 2000-12-26 |
JP2002505282A (ja) | 2002-02-19 |
BR9908479A (pt) | 2000-12-05 |
EA200000897A1 (ru) | 2001-02-26 |
WO1999044604A9 (en) | 2000-01-20 |
NO20004306D0 (no) | 2000-08-29 |
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