TR200002255T2 - Bifenilsülfonilsiyonamidler, üretim yöntemi ve ilaç olarak kullanımları. - Google Patents
Bifenilsülfonilsiyonamidler, üretim yöntemi ve ilaç olarak kullanımları.Info
- Publication number
- TR200002255T2 TR200002255T2 TR2000/02255T TR200002255T TR200002255T2 TR 200002255 T2 TR200002255 T2 TR 200002255T2 TR 2000/02255 T TR2000/02255 T TR 2000/02255T TR 200002255 T TR200002255 T TR 200002255T TR 200002255 T2 TR200002255 T2 TR 200002255T2
- Authority
- TR
- Turkey
- Prior art keywords
- compounds
- biphenylsulphonylionamides
- drugs
- production method
- ischemic
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 230000000302 ischemic effect Effects 0.000 abstract 2
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 230000006793 arrhythmia Effects 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000003293 cardioprotective effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000001991 pathophysiological effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/47—Y being a hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19804251A DE19804251A1 (de) | 1998-02-04 | 1998-02-04 | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200002255T2 true TR200002255T2 (tr) | 2001-06-21 |
Family
ID=7856542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02255T TR200002255T2 (tr) | 1998-02-04 | 1999-02-04 | Bifenilsülfonilsiyonamidler, üretim yöntemi ve ilaç olarak kullanımları. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6369069B1 (enExample) |
| EP (1) | EP1053224B1 (enExample) |
| JP (1) | JP4464559B2 (enExample) |
| KR (1) | KR100595353B1 (enExample) |
| CN (1) | CN1231465C (enExample) |
| AR (1) | AR016448A1 (enExample) |
| AT (1) | ATE222584T1 (enExample) |
| AU (1) | AU758154B2 (enExample) |
| BR (1) | BR9907667A (enExample) |
| CA (1) | CA2319555A1 (enExample) |
| DE (2) | DE19804251A1 (enExample) |
| DK (1) | DK1053224T3 (enExample) |
| ES (1) | ES2182504T3 (enExample) |
| HU (1) | HU224618B1 (enExample) |
| PL (1) | PL342453A1 (enExample) |
| PT (1) | PT1053224E (enExample) |
| RU (1) | RU2247111C2 (enExample) |
| TR (1) | TR200002255T2 (enExample) |
| WO (1) | WO1999040064A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19820064A1 (de) | 1998-05-06 | 1999-11-11 | Hoechst Marion Roussel De Gmbh | Substituierte Sulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| US6906069B1 (en) | 1999-01-08 | 2005-06-14 | Amgen Inc. | LXR modulators |
| AU2000235960A1 (en) * | 2000-02-14 | 2001-08-27 | Tularik, Inc. | Lxr modulators |
| AU2001278480A1 (en) | 2000-07-24 | 2002-02-05 | Bayer Crop Science Ag | Biphenyl carboxamides |
| AU2003208952B2 (en) | 2002-01-30 | 2008-04-24 | Amgen Inc. | Heterocyclic arylsulfonamidobenzylic compounds |
| DE10206354A1 (de) * | 2002-02-14 | 2003-08-28 | Aventis Pharma Gmbh | Verwendung von Inhibitoren des Natrium-abhängigen Chlorid-Bicarbonat-Austauschers zur Behandlung von thrombotischen und inflammatorischer Erkrankungen |
| MX2008013194A (es) * | 2006-04-11 | 2008-12-01 | Vertex Pharma | Composiciones utiles como inhibidores de canales de sodio regulados por voltaje. |
| WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2062558A1 (en) * | 1991-03-08 | 1992-09-09 | Prasun K. Chakravarty | Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists |
| EP0586513A1 (en) * | 1991-05-10 | 1994-03-16 | Merck & Co. Inc. | Acidic aralkyl triazole derivatives active as angiotensin ii antagonists |
| FR2716883B1 (fr) * | 1994-03-04 | 1996-04-26 | Roussel Uclaf | Nouveaux dérivés tétrasubstitués de l'imidazole, leur préparation, nouveaux intermédiaires obtenus, leur application à titre de médicaments, compositions pharmaceutiques les renfermant. |
| EP0855392A3 (de) * | 1997-01-22 | 2000-01-05 | Hoechst Aktiengesellschaft | Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19741635A1 (de) | 1997-09-22 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
-
1998
- 1998-02-04 DE DE19804251A patent/DE19804251A1/de not_active Withdrawn
-
1999
- 1999-02-04 EP EP99913138A patent/EP1053224B1/de not_active Expired - Lifetime
- 1999-02-04 WO PCT/EP1999/000724 patent/WO1999040064A1/de not_active Ceased
- 1999-02-04 AT AT99913138T patent/ATE222584T1/de not_active IP Right Cessation
- 1999-02-04 DK DK99913138T patent/DK1053224T3/da active
- 1999-02-04 TR TR2000/02255T patent/TR200002255T2/xx unknown
- 1999-02-04 US US09/601,630 patent/US6369069B1/en not_active Expired - Lifetime
- 1999-02-04 HU HU0102576A patent/HU224618B1/hu not_active IP Right Cessation
- 1999-02-04 CN CNB998026611A patent/CN1231465C/zh not_active Expired - Fee Related
- 1999-02-04 PL PL99342453A patent/PL342453A1/xx not_active Application Discontinuation
- 1999-02-04 KR KR1020007008433A patent/KR100595353B1/ko not_active Expired - Fee Related
- 1999-02-04 RU RU2000122850/04A patent/RU2247111C2/ru not_active IP Right Cessation
- 1999-02-04 ES ES99913138T patent/ES2182504T3/es not_active Expired - Lifetime
- 1999-02-04 PT PT99913138T patent/PT1053224E/pt unknown
- 1999-02-04 BR BR9907667-5A patent/BR9907667A/pt not_active Application Discontinuation
- 1999-02-04 JP JP2000530496A patent/JP4464559B2/ja not_active Expired - Fee Related
- 1999-02-04 DE DE59902408T patent/DE59902408D1/de not_active Expired - Lifetime
- 1999-02-04 AU AU31398/99A patent/AU758154B2/en not_active Ceased
- 1999-02-04 CA CA002319555A patent/CA2319555A1/en not_active Abandoned
- 1999-02-05 AR ARP990100482A patent/AR016448A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0102576A1 (hu) | 2002-03-28 |
| RU2247111C2 (ru) | 2005-02-27 |
| ES2182504T3 (es) | 2003-03-01 |
| HU224618B1 (hu) | 2005-11-28 |
| EP1053224A1 (de) | 2000-11-22 |
| JP2002502840A (ja) | 2002-01-29 |
| WO1999040064A1 (de) | 1999-08-12 |
| KR100595353B1 (ko) | 2006-07-03 |
| PL342453A1 (en) | 2001-06-04 |
| HK1034706A1 (en) | 2001-11-02 |
| AU3139899A (en) | 1999-08-23 |
| AU758154B2 (en) | 2003-03-13 |
| DE19804251A1 (de) | 1999-08-05 |
| DE59902408D1 (de) | 2002-09-26 |
| EP1053224B1 (de) | 2002-08-21 |
| BR9907667A (pt) | 2000-10-24 |
| HUP0102576A3 (en) | 2002-12-28 |
| ATE222584T1 (de) | 2002-09-15 |
| PT1053224E (pt) | 2002-12-31 |
| CN1231465C (zh) | 2005-12-14 |
| US6369069B1 (en) | 2002-04-09 |
| JP4464559B2 (ja) | 2010-05-19 |
| DK1053224T3 (da) | 2002-12-23 |
| AR016448A1 (es) | 2001-07-04 |
| CA2319555A1 (en) | 1999-08-12 |
| KR20010040564A (ko) | 2001-05-15 |
| CN1289321A (zh) | 2001-03-28 |
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