TR200002019T2 - 1,3,4-Okzadiazolon türevleri. - Google Patents

1,3,4-Okzadiazolon türevleri.

Info

Publication number
TR200002019T2
TR200002019T2 TR2000/02019T TR200002019T TR200002019T2 TR 200002019 T2 TR200002019 T2 TR 200002019T2 TR 2000/02019 T TR2000/02019 T TR 2000/02019T TR 200002019 T TR200002019 T TR 200002019T TR 200002019 T2 TR200002019 T2 TR 200002019T2
Authority
TR
Turkey
Prior art keywords
formula
oxadiazolone derivatives
oxadiazolone
derivatives
solvate
Prior art date
Application number
TR2000/02019T
Other languages
English (en)
Inventor
Hewawasam Piyasena
Ding Min
E. Jr. Starrett John
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of TR200002019T2 publication Critical patent/TR200002019T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Mevcut bulus; yüksek ölçüde iletkenlige sahip kalsiyum-aktivasyonlu potasyum kanallarinin açilmasinin sorumlulugundaki rahatsizliklarin tedavisinde faydali olan, içerisinde A,B,D ve R' nin yukarida tanimlandigi gibi oldugu genel formüle Formül (I) sahip, yeni okzadiazolon türevlerini veya bunlarin toksik olmayan, farmasötik olarak kabul edilebilen bir tuzu veya solvatini saglamaktadir.
TR2000/02019T 1998-01-29 1999-01-15 1,3,4-Okzadiazolon türevleri. TR200002019T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7296698P 1998-01-29 1998-01-29
US10227498P 1998-09-29 1998-09-29

Publications (1)

Publication Number Publication Date
TR200002019T2 true TR200002019T2 (tr) 2000-11-21

Family

ID=26753969

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02019T TR200002019T2 (tr) 1998-01-29 1999-01-15 1,3,4-Okzadiazolon türevleri.

Country Status (27)

Country Link
US (1) US6034113A (tr)
EP (1) EP1051173A4 (tr)
JP (1) JP2002527352A (tr)
KR (1) KR20010077838A (tr)
CN (1) CN1150175C (tr)
AR (1) AR010712A1 (tr)
AU (1) AU735704B2 (tr)
BG (1) BG104706A (tr)
BR (1) BR9913010A (tr)
CA (1) CA2318830A1 (tr)
CO (1) CO5090837A1 (tr)
EE (1) EE04089B1 (tr)
GE (1) GEP20032914B (tr)
HU (1) HUP0102025A3 (tr)
ID (1) ID26909A (tr)
IL (1) IL137518A0 (tr)
LT (1) LT4838B (tr)
LV (1) LV12559B (tr)
NO (1) NO317102B1 (tr)
NZ (1) NZ505409A (tr)
PL (1) PL342060A1 (tr)
RU (1) RU2202548C2 (tr)
SK (1) SK10852000A3 (tr)
TR (1) TR200002019T2 (tr)
TW (1) TW550075B (tr)
UA (1) UA58579C2 (tr)
WO (1) WO1999038510A1 (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU736599B2 (en) * 1998-01-29 2001-08-02 Bristol-Myers Squibb Company Amino acid derivatives of diaryl 1,3,4-oxadiazolone
US6297241B1 (en) 1999-01-29 2001-10-02 Bristol-Myers Squibb Company Carbamate derivatives of diaryl 1,3,4-oxadiazolone
ID29269A (id) * 1999-01-29 2001-08-16 Bristol Myers Squibb Co Turunan-turunan karbamat dari diaril 1,3,4,oksadiazolon
US6326388B1 (en) * 1999-12-21 2001-12-04 Celgene Corporation Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level
US6855829B2 (en) 2001-02-20 2005-02-15 Bristol-Myers Squibb Company 3-fluoro-2-oxindole modulators of KCNQ potassium channels and use thereof in treating migraine and mechanistically related disease
AU2002246397B2 (en) * 2001-04-16 2005-03-24 Tanabe Seiyaku Co., Ltd. Imidazole, thiazole and oxazole derivatives and their use for the manufacture of a medicament for the treatment and/or prevention of pollakiuria or urinary incontinence
US6909027B1 (en) * 2001-08-13 2005-06-21 Perry Robins Method of forming an in-situ film dressing and the composition of the film-forming material
US7119246B2 (en) * 2002-06-25 2006-10-10 Perry Robins Method of treating acne
WO2013170655A1 (en) 2012-05-16 2013-11-21 Techfields Pharma Co., Ltd. High penetration prodrug compositions and pharmaceutical composition thereof for treatment of pulmonary conditions
JP5855599B2 (ja) * 2013-04-30 2016-02-09 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
CN104710379B (zh) * 2015-03-09 2017-01-18 华南理工大学 一种bms‑191011的合成方法
JP6165816B2 (ja) * 2015-10-01 2017-07-19 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
MX2019009985A (es) * 2017-02-24 2019-10-09 Ovid Therapeutics Inc Metodos para tratar trastornos convulsivos.
CN110987847B (zh) * 2019-12-11 2021-02-19 苏州今蓝纳米科技有限公司 1,3,4-噁二唑衍生物在检测酸以及数据加密和储存中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH583213A5 (tr) * 1973-05-21 1976-12-31 Ciba Geigy Ag
IT1251488B (it) * 1991-09-17 1995-05-15 Mini Ricerca Scient Tecnolog Ossa(tia)diazol- e triazol-oni(tioni) ad attivita' acaricida ed insetticida
US5234947A (en) * 1991-11-07 1993-08-10 New York University Potassium channel activating compounds and methods of use thereof
US5547966A (en) * 1993-10-07 1996-08-20 Bristol-Myers Squibb Company Aryl urea and related compounds
TW467902B (en) * 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators
AU736599B2 (en) * 1998-01-29 2001-08-02 Bristol-Myers Squibb Company Amino acid derivatives of diaryl 1,3,4-oxadiazolone

Also Published As

Publication number Publication date
GEP20032914B (en) 2003-03-25
NZ505409A (en) 2003-08-29
EE200000447A (et) 2001-12-17
UA58579C2 (uk) 2003-08-15
AU735704B2 (en) 2001-07-12
AR010712A1 (es) 2000-07-12
AU2230899A (en) 1999-08-16
IL137518A0 (en) 2001-07-24
JP2002527352A (ja) 2002-08-27
BG104706A (en) 2001-04-30
CO5090837A1 (es) 2001-10-30
HUP0102025A3 (en) 2002-01-28
CN1289249A (zh) 2001-03-28
NO317102B1 (no) 2004-08-09
HUP0102025A2 (hu) 2001-11-28
LV12559A (en) 2000-11-20
LT4838B (lt) 2001-08-27
LT2000068A (en) 2001-03-26
US6034113A (en) 2000-03-07
NO20003825L (no) 2000-07-26
LV12559B (en) 2001-04-20
WO1999038510A1 (en) 1999-08-05
KR20010077838A (ko) 2001-08-20
CA2318830A1 (en) 1999-08-05
SK10852000A3 (sk) 2002-02-05
EE04089B1 (et) 2003-08-15
NO20003825D0 (no) 2000-07-26
RU2202548C2 (ru) 2003-04-20
TW550075B (en) 2003-09-01
EP1051173A4 (en) 2002-07-31
CN1150175C (zh) 2004-05-19
EP1051173A1 (en) 2000-11-15
ID26909A (id) 2001-02-15
PL342060A1 (en) 2001-05-21
BR9913010A (pt) 2001-05-08

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