TR199903062T2 - 3-Ikameli 3,4-Dihidro-Tiyeno(2,3-D) Pirimidin-Türevleri, bunlarin imal edilmesi ve kullanimi. - Google Patents

3-Ikameli 3,4-Dihidro-Tiyeno(2,3-D) Pirimidin-Türevleri, bunlarin imal edilmesi ve kullanimi.

Info

Publication number
TR199903062T2
TR199903062T2 TR1999/03062T TR9903062T TR199903062T2 TR 199903062 T2 TR199903062 T2 TR 199903062T2 TR 1999/03062 T TR1999/03062 T TR 1999/03062T TR 9903062 T TR9903062 T TR 9903062T TR 199903062 T2 TR199903062 T2 TR 199903062T2
Authority
TR
Turkey
Prior art keywords
substituted
thieno
dihydro
amino
necessary
Prior art date
Application number
TR1999/03062T
Other languages
English (en)
Inventor
Steiner Gerd
Dullweber Uta
Starck Dorothea
Bach Alfred
Wicke Karsten
Teschendorf Hans-Jurgen
Garcia-Ladona Francisco-Javier
Emling Franz
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of TR199903062T2 publication Critical patent/TR199903062T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Formül (I)' in 3-ikameli 3,4-dihidro-tiyeno (2,3-d) pirimidin - türevleri, ki bunun içerisinde R1 ve R2 bir hidrojen atomu veya bir C1-C4-alkil grubu anlamina gelmektedir, R3 gerekirse halojen atomlari, C1-C4-alkil, trifluormetil-, trifluormetoksi-, hidroksi-, C1-C4-alkoksi-, amino-, monometilamino-, dimetil-amino-, siyano- veya nitro gruplari ile mono veya di olarak ikame edilen fenil-, piridil-, pirimidinil- veya pirazinil grubu anlamina gelir, bu grup ise gerekirse benzol çekirdegi ile, ki bu halojen atomlari, C1-C4-alkil-, hidroksi-, trifluormetil-, C1-C4-alkoksi-, amino-, siyano- veya nitro gruplariyla mono veya di halde ikame edilebilir ve gerekirse 1 nitrojen atomu içerebilir, veya 1-2 oksijen atomu içerebilecek olan bir 5- veya 6- bölümlemeli halka ile anele edilebilir.
TR1999/03062T 1997-06-13 1998-05-29 3-Ikameli 3,4-Dihidro-Tiyeno(2,3-D) Pirimidin-Türevleri, bunlarin imal edilmesi ve kullanimi. TR199903062T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19724980A DE19724980A1 (de) 1997-06-13 1997-06-13 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
TR199903062T2 true TR199903062T2 (tr) 2000-06-21

Family

ID=7832352

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/03062T TR199903062T2 (tr) 1997-06-13 1998-05-29 3-Ikameli 3,4-Dihidro-Tiyeno(2,3-D) Pirimidin-Türevleri, bunlarin imal edilmesi ve kullanimi.

Country Status (25)

Country Link
US (1) US6159962A (tr)
EP (1) EP0988306B1 (tr)
JP (1) JP2002504103A (tr)
KR (1) KR20010013696A (tr)
CN (1) CN1260797A (tr)
AR (1) AR015712A1 (tr)
AT (1) ATE244720T1 (tr)
AU (1) AU749320B2 (tr)
BG (1) BG103900A (tr)
BR (1) BR9810017A (tr)
CA (1) CA2293816A1 (tr)
CO (1) CO4940507A1 (tr)
CZ (1) CZ290464B6 (tr)
DE (2) DE19724980A1 (tr)
HR (1) HRP980319A2 (tr)
HU (1) HUP0002902A3 (tr)
ID (1) ID23421A (tr)
IL (1) IL132967A0 (tr)
NO (1) NO996043D0 (tr)
NZ (1) NZ502238A (tr)
PL (1) PL337453A1 (tr)
SK (1) SK168499A3 (tr)
TR (1) TR199903062T2 (tr)
WO (1) WO1998056792A1 (tr)
ZA (1) ZA985121B (tr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2205179C2 (ru) 1997-10-27 2003-05-27 НьюроСёрч А/С Производное гомопиперазина и фармацевтическая композиция
DE19900545A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
WO2001064683A1 (fr) * 2000-02-29 2001-09-07 Takeda Chemical Industries, Ltd. Procedes de production de derives de thienopyramidine
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
BRPI0408988A (pt) * 2003-03-31 2006-03-28 Predix Pharmaceuticals Holding composto de piperidinilamino-tieno[2,3-d]pirimidina
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US8349850B2 (en) 2006-03-28 2013-01-08 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
EP2896624B1 (en) * 2007-03-28 2016-07-13 Atir Holding S.A. Heterotricyclic compounds as serotonergic and/or dopaminergic agents and uses thereof
WO2008138126A1 (en) * 2007-05-09 2008-11-20 Neuromed Pharmaceuticals Ltd. Bicyclic pyrimidine derivatives as calcium channel blockers
WO2010065743A2 (en) * 2008-12-03 2010-06-10 Nanotherapeutics, Inc. Bicyclic compounds and methods of making and using same
JP5722781B2 (ja) * 2009-08-26 2015-05-27 武田薬品工業株式会社 縮合複素環誘導体およびその用途
US9353067B2 (en) 2011-04-10 2016-05-31 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
US9671052B2 (en) 2015-10-27 2017-06-06 Whirlpool Corporation Collet securing device for joining two fluid lines and providing lateral support at the connection of the two fluid lines
US10557469B2 (en) 2016-03-22 2020-02-11 Whirlpool Corporation Multi-outlet fluid flow system for an appliance incorporating a bi-directional motor
US10655266B2 (en) 2016-11-30 2020-05-19 Whirlpool Corporation Lint processing fluid pump for a laundry appliance
US10480117B2 (en) 2017-02-27 2019-11-19 Whirlpool Corporation Self cleaning sump cover
US10619289B2 (en) 2017-02-27 2020-04-14 Whirlpool Corporation Self cleaning diverter valve
US10662574B2 (en) 2017-02-27 2020-05-26 Whirlpool Corporation Self cleaning heater exchanger plate
US10634412B2 (en) 2017-04-10 2020-04-28 Whirlpool Corporation Concealed upstream air tower guide vanes
WO2020183011A1 (en) 2019-03-14 2020-09-17 Institut Curie Htr1d inhibitors and uses thereof in the treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4835157A (en) * 1988-03-15 1989-05-30 Ortho Pharmaceutical Corporation Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents
DE19636769A1 (de) * 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
NO996043L (no) 1999-12-08
EP0988306B1 (de) 2003-07-09
CZ443199A3 (cs) 2000-06-14
BR9810017A (pt) 2000-09-19
NO996043D0 (no) 1999-12-08
DE59808992D1 (de) 2003-08-14
SK168499A3 (en) 2000-05-16
EP0988306A1 (de) 2000-03-29
NZ502238A (en) 2001-02-23
HUP0002902A3 (en) 2002-09-30
HRP980319A2 (en) 1999-04-30
CN1260797A (zh) 2000-07-19
IL132967A0 (en) 2001-03-19
KR20010013696A (ko) 2001-02-26
ZA985121B (en) 1999-12-13
AU7917698A (en) 1998-12-30
CA2293816A1 (en) 1998-12-17
DE19724980A1 (de) 1998-12-17
AR015712A1 (es) 2001-05-16
PL337453A1 (en) 2000-08-14
JP2002504103A (ja) 2002-02-05
US6159962A (en) 2000-12-12
BG103900A (en) 2000-06-30
ID23421A (id) 2000-04-20
HUP0002902A2 (hu) 2001-02-28
CO4940507A1 (es) 2000-07-24
CZ290464B6 (cs) 2002-07-17
AU749320B2 (en) 2002-06-20
WO1998056792A1 (de) 1998-12-17
ATE244720T1 (de) 2003-07-15

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