TR199802168T2 - IL-16 Aktivitesine sahip islenmis polipeptidler, bunlari üretmeye mahsus yöntemler ve bunlarin kullanimi. - Google Patents
IL-16 Aktivitesine sahip islenmis polipeptidler, bunlari üretmeye mahsus yöntemler ve bunlarin kullanimi.Info
- Publication number
- TR199802168T2 TR199802168T2 TR1998/02168T TR9802168T TR199802168T2 TR 199802168 T2 TR199802168 T2 TR 199802168T2 TR 1998/02168 T TR1998/02168 T TR 1998/02168T TR 9802168 T TR9802168 T TR 9802168T TR 199802168 T2 TR199802168 T2 TR 199802168T2
- Authority
- TR
- Turkey
- Prior art keywords
- activity
- producing
- methods
- sequence
- processed polypeptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5446—IL-16
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Bir prokaryotik veya ökaryotik konak hücre içinde interlökin-16 aktivitesine sahip bir polipeptidin ekspresyonunu yapmak için kullanilabilen bir nükleik asit olup, burada söz konusu nükleik asit, Dizi tanim nO: 2'deki veya N-terminalinde bir aspartik asit kalintisi ile uzatilmis veya C-terminalinde 8 taneye kadar amino asidi kisaltilmis haldeki bir Dizi tanim no: 2'ye ait amino asit dizimine sahip bir polipeptid için kodlama yapar ve aktif IL-16 polipeptidi üretimi için uygundur.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1996117203 DE19617203A1 (de) | 1996-04-30 | 1996-04-30 | Prozessierte Polypeptide mit IL-16-Aktivität, Verfahren zu ihrer Herstellung und Verwendung |
DE19617202A DE19617202A1 (de) | 1996-04-30 | 1996-04-30 | Prozessierte Polypeptide mit IL-16-Aktivität, Verfahren zu ihrer Herstellung und Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199802168T2 true TR199802168T2 (tr) | 1999-02-22 |
Family
ID=26025242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1998/02168T TR199802168T2 (tr) | 1996-04-30 | 1997-04-30 | IL-16 Aktivitesine sahip islenmis polipeptidler, bunlari üretmeye mahsus yöntemler ve bunlarin kullanimi. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6506582B1 (tr) |
EP (1) | EP0904374A1 (tr) |
JP (1) | JP3251592B2 (tr) |
KR (1) | KR100308441B1 (tr) |
CN (1) | CN1217025A (tr) |
AU (1) | AU712122B2 (tr) |
BR (1) | BR9709205A (tr) |
CA (1) | CA2253259A1 (tr) |
DE (1) | DE19780377D2 (tr) |
TR (1) | TR199802168T2 (tr) |
WO (1) | WO1997041231A1 (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090130661A1 (en) * | 2006-09-28 | 2009-05-21 | Glass William G | Method for Detecting IL-16 Activity and Modulation of IL-16 Activity Based on Phosphorylated Stat-6 Proxy Levels |
EP2094305A4 (en) * | 2006-10-27 | 2011-01-05 | Centocor Ortho Biotech Inc | METHODS FOR TREATING PULMONARY DISEASES AND BLÉOMYCINE-INDUCED PULMONARY FIBROSIS |
US20110217259A1 (en) * | 2010-03-03 | 2011-09-08 | Djordje Atanackovic | IL-16 as a target for diagnosis and therapy of hematological malignancies and solid tumors |
CN114984189A (zh) * | 2022-05-27 | 2022-09-02 | 昆明理工大学 | 一种白细胞介素16蛋白的新用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
GB9214857D0 (en) * | 1992-07-13 | 1992-08-26 | Medical Res Council | Human nucleic acid fragments and their use |
ES2320090T3 (es) * | 1993-05-21 | 2009-05-19 | Trustees Of Boston University | Factor quimiotactico de linfocitos y usos del mismo. |
DE19513152A1 (de) | 1995-04-07 | 1996-10-10 | Bundesrep Deutschland | Verwendung eines "Immundefizienzvirus-supprimierenden Lymphokins (ISL)" zur Hemmung der Virusvermehrung, insbesondere von Retroviren |
-
1997
- 1997-04-30 CN CN97194250A patent/CN1217025A/zh active Pending
- 1997-04-30 BR BR9709205-3A patent/BR9709205A/pt not_active Application Discontinuation
- 1997-04-30 AU AU27752/97A patent/AU712122B2/en not_active Ceased
- 1997-04-30 CA CA002253259A patent/CA2253259A1/en not_active Abandoned
- 1997-04-30 JP JP53859497A patent/JP3251592B2/ja not_active Expired - Fee Related
- 1997-04-30 WO PCT/EP1997/002216 patent/WO1997041231A1/de not_active Application Discontinuation
- 1997-04-30 DE DE19780377T patent/DE19780377D2/de not_active Ceased
- 1997-04-30 EP EP97921834A patent/EP0904374A1/de not_active Withdrawn
- 1997-04-30 KR KR1019980708540A patent/KR100308441B1/ko not_active IP Right Cessation
- 1997-04-30 TR TR1998/02168T patent/TR199802168T2/tr unknown
- 1997-04-30 US US09/171,962 patent/US6506582B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2253259A1 (en) | 1997-11-06 |
US6506582B1 (en) | 2003-01-14 |
JP3251592B2 (ja) | 2002-01-28 |
DE19780377D2 (de) | 1999-08-05 |
KR100308441B1 (ko) | 2001-11-02 |
JPH11508453A (ja) | 1999-07-27 |
KR20000065005A (ko) | 2000-11-06 |
CN1217025A (zh) | 1999-05-19 |
EP0904374A1 (de) | 1999-03-31 |
AU2775297A (en) | 1997-11-19 |
BR9709205A (pt) | 2000-01-11 |
AU712122B2 (en) | 1999-10-28 |
WO1997041231A1 (de) | 1997-11-06 |
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