DK1032672T3 - DNA19355-polypeptid, en tumornekrosefaktor-homolog - Google Patents
DNA19355-polypeptid, en tumornekrosefaktor-homologInfo
- Publication number
- DK1032672T3 DK1032672T3 DK98958067T DK98958067T DK1032672T3 DK 1032672 T3 DK1032672 T3 DK 1032672T3 DK 98958067 T DK98958067 T DK 98958067T DK 98958067 T DK98958067 T DK 98958067T DK 1032672 T3 DK1032672 T3 DK 1032672T3
- Authority
- DK
- Denmark
- Prior art keywords
- dna19355
- necrosis factor
- tumor necrosis
- dna19355 polypeptide
- factor homologue
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6563597P | 1997-11-18 | 1997-11-18 | |
US6966197P | 1997-12-12 | 1997-12-12 | |
PCT/US1998/024621 WO1999025834A1 (en) | 1997-11-18 | 1998-11-18 | Dna19355 polypeptide, a tumor necrosis factor homolog |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1032672T3 true DK1032672T3 (da) | 2009-04-27 |
Family
ID=26745805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98958067T DK1032672T3 (da) | 1997-11-18 | 1998-11-18 | DNA19355-polypeptid, en tumornekrosefaktor-homolog |
Country Status (12)
Country | Link |
---|---|
US (4) | US20020146389A1 (da) |
EP (1) | EP1032672B1 (da) |
JP (2) | JP4485049B2 (da) |
AT (1) | ATE419357T1 (da) |
AU (1) | AU760010B2 (da) |
CA (1) | CA2308365A1 (da) |
DE (1) | DE69840413D1 (da) |
DK (1) | DK1032672T3 (da) |
ES (1) | ES2320285T3 (da) |
IL (1) | IL135911A0 (da) |
PT (1) | PT1032672E (da) |
WO (1) | WO1999025834A1 (da) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6406867B1 (en) | 1996-08-16 | 2002-06-18 | Human Genome Sciences, Inc. | Antibody to human endokine alpha and methods of use |
WO2001040464A1 (en) * | 1999-11-30 | 2001-06-07 | Genentech, Inc. | Interleukin-1-receptor associated kinase-3 (irak3) and its use in promotion or inhibition of angiogenesis and cardiovascularization |
AU5441200A (en) * | 1999-06-02 | 2000-12-18 | Genentech Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
IL147442A0 (en) * | 1999-07-12 | 2002-08-14 | Genentech Inc | Promotion or inhibition of angiogenesis and cardiovscularization by tumor necrosis factor ligand/receptor homologs |
AU6391000A (en) * | 1999-07-28 | 2001-02-19 | Genentech Inc. | Method of preventing the injury or death of retinal cells and treating ocular diseases |
DE10045591A1 (de) * | 2000-09-15 | 2002-04-04 | Klaus Pfizenmaier | Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine) |
US20030133936A1 (en) * | 2001-07-12 | 2003-07-17 | Byrne Michael Chapman | CD25markers and uses thereof |
US7087225B2 (en) * | 2001-08-16 | 2006-08-08 | Human Genome Sciences, Inc. | Methods and compositions for treating metabolic bone diseases relating to human endokine alpha |
KR20040099418A (ko) * | 2002-04-08 | 2004-11-26 | 다케다 야쿠힌 고교 가부시키가이샤 | 중증 패혈증 예방 치료제 |
EP1631588A2 (en) * | 2003-05-23 | 2006-03-08 | Wyeth | Gitr ligand and gitr ligand-related molecules and antibodies and uses thereof |
WO2005007190A1 (en) * | 2003-07-11 | 2005-01-27 | Schering Corporation | Agonists or antagonists of the clucocorticoid-induced tumour necrosis factor receptor (gitr) or its ligand for the treatment of immune disorders, infections and cancer |
WO2005055808A2 (en) * | 2003-12-02 | 2005-06-23 | Genzyme Corporation | Compositions and methods to diagnose and treat lung cancer |
US20070065889A1 (en) * | 2004-12-02 | 2007-03-22 | Roberts Bruce L | Compositions and methods to diagnose and treat lung cancer |
TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
SG10201810507WA (en) | 2014-06-06 | 2018-12-28 | Bristol Myers Squibb Co | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof |
MA41460A (fr) | 2015-02-03 | 2017-12-12 | Oncomed Pharm Inc | Agents de liaison à la tnfrsf et leurs utilisations |
EA201792497A1 (ru) | 2015-06-03 | 2018-05-31 | Бристол-Майерс Сквибб Компани | Антитела к gitr для диагностики злокачественной опухоли |
WO2017087678A2 (en) | 2015-11-19 | 2017-05-26 | Bristol-Myers Squibb Company | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof |
MA45233A (fr) | 2016-06-10 | 2019-04-17 | Regeneron Pharma | Anticorps anti-gitr et leurs utilisations |
KR20200006115A (ko) | 2017-05-16 | 2020-01-17 | 브리스톨-마이어스 스큅 컴퍼니 | 항-gitr 효능제 항체에 의한 암의 치료 |
CN115244084A (zh) | 2020-03-06 | 2022-10-25 | 瑞泽恩制药公司 | 抗gitr抗体及其用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288852A (en) * | 1984-03-06 | 1994-02-22 | Dainippon Pharmaceutical Co., Ltd. | Human tumor necrosis factor polypeptides |
KR101004174B1 (ko) * | 1995-06-29 | 2010-12-24 | 임뮤넥스 코포레이션 | 세포소멸을 유도하는 시토킨 |
US6406867B1 (en) * | 1996-08-16 | 2002-06-18 | Human Genome Sciences, Inc. | Antibody to human endokine alpha and methods of use |
DK0961831T3 (da) * | 1996-08-16 | 2009-01-12 | Human Genome Sciences Inc | Humant alfa-endokin |
US5998171A (en) * | 1996-08-16 | 1999-12-07 | Human Genome Sciences, Inc. | Polynucleotides encoding human endokine alpha |
-
1998
- 1998-11-18 EP EP98958067A patent/EP1032672B1/en not_active Expired - Lifetime
- 1998-11-18 PT PT98958067T patent/PT1032672E/pt unknown
- 1998-11-18 DE DE69840413T patent/DE69840413D1/de not_active Expired - Lifetime
- 1998-11-18 CA CA002308365A patent/CA2308365A1/en not_active Abandoned
- 1998-11-18 WO PCT/US1998/024621 patent/WO1999025834A1/en active IP Right Grant
- 1998-11-18 IL IL13591198A patent/IL135911A0/xx unknown
- 1998-11-18 DK DK98958067T patent/DK1032672T3/da active
- 1998-11-18 AT AT98958067T patent/ATE419357T1/de active
- 1998-11-18 AU AU14180/99A patent/AU760010B2/en not_active Expired
- 1998-11-18 ES ES98958067T patent/ES2320285T3/es not_active Expired - Lifetime
- 1998-11-18 JP JP2000521199A patent/JP4485049B2/ja not_active Expired - Lifetime
-
2002
- 2002-02-22 US US10/080,455 patent/US20020146389A1/en not_active Abandoned
-
2003
- 2003-11-14 US US10/713,391 patent/US20040234498A1/en not_active Abandoned
-
2005
- 2005-05-06 US US11/123,992 patent/US20070072263A1/en not_active Abandoned
-
2006
- 2006-02-14 US US11/353,441 patent/US20060216270A1/en not_active Abandoned
-
2009
- 2009-12-11 JP JP2009281737A patent/JP2010088448A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ATE419357T1 (de) | 2009-01-15 |
US20040234498A1 (en) | 2004-11-25 |
WO1999025834A1 (en) | 1999-05-27 |
US20070072263A1 (en) | 2007-03-29 |
DE69840413D1 (de) | 2009-02-12 |
IL135911A0 (en) | 2001-05-20 |
AU1418099A (en) | 1999-06-07 |
CA2308365A1 (en) | 1999-05-27 |
JP2001523459A (ja) | 2001-11-27 |
US20060216270A1 (en) | 2006-09-28 |
US20020146389A1 (en) | 2002-10-10 |
JP4485049B2 (ja) | 2010-06-16 |
AU760010B2 (en) | 2003-05-08 |
JP2010088448A (ja) | 2010-04-22 |
EP1032672B1 (en) | 2008-12-31 |
ES2320285T3 (es) | 2009-05-20 |
EP1032672A1 (en) | 2000-09-06 |
PT1032672E (pt) | 2009-04-02 |
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