TR199801235T2 - Inhibitörlerin solunum stimülasyonuna yönelik ilaç üretiminde kullanimi. - Google Patents
Inhibitörlerin solunum stimülasyonuna yönelik ilaç üretiminde kullanimi.Info
- Publication number
- TR199801235T2 TR199801235T2 TR1998/01235T TR9801235T TR199801235T2 TR 199801235 T2 TR199801235 T2 TR 199801235T2 TR 1998/01235 T TR1998/01235 T TR 1998/01235T TR 9801235 T TR9801235 T TR 9801235T TR 199801235 T2 TR199801235 T2 TR 199801235T2
- Authority
- TR
- Turkey
- Prior art keywords
- inhibitors
- drugs
- manufacture
- respiratory stimulation
- stimulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L50/00—Electric propulsion with power supplied within the vehicle
- B60L50/50—Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells
- B60L50/60—Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells using power supplied by batteries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L7/00—Electrodynamic brake systems for vehicles in general
- B60L7/10—Dynamic electric regenerative braking
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L7/00—Electrodynamic brake systems for vehicles in general
- B60L7/10—Dynamic electric regenerative braking
- B60L7/16—Dynamic electric regenerative braking for vehicles comprising converters between the power source and the motor
-
- E—FIXED CONSTRUCTIONS
- E01—CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
- E01C—CONSTRUCTION OF, OR SURFACES FOR, ROADS, SPORTS GROUNDS, OR THE LIKE; MACHINES OR AUXILIARY TOOLS FOR CONSTRUCTION OR REPAIR
- E01C19/00—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving
- E01C19/22—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving for consolidating or finishing laid-down unset materials
- E01C19/23—Rollers therefor; Such rollers usable also for compacting soil
- E01C19/26—Rollers therefor; Such rollers usable also for compacting soil self-propelled or fitted to road vehicles
-
- E—FIXED CONSTRUCTIONS
- E01—CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
- E01C—CONSTRUCTION OF, OR SURFACES FOR, ROADS, SPORTS GROUNDS, OR THE LIKE; MACHINES OR AUXILIARY TOOLS FOR CONSTRUCTION OR REPAIR
- E01C19/00—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving
- E01C19/22—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving for consolidating or finishing laid-down unset materials
- E01C19/23—Rollers therefor; Such rollers usable also for compacting soil
- E01C19/28—Vibrated rollers or rollers subjected to impacts, e.g. hammering blows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Mechanical Engineering (AREA)
- Transportation (AREA)
- Power Engineering (AREA)
- Civil Engineering (AREA)
- Architecture (AREA)
- Structural Engineering (AREA)
- Sustainable Energy (AREA)
- Sustainable Development (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
NHE-inhibitörleri olarak tanimlanan aktif maddeler nefes stimülasyonuna yönelik bir ilacin üretimi için mükemmel derecede uygundur. Inhibitörler özellikle uyku apnesi ya da diger solunum rahatsizliklarinin tedavi edilmesi için uygun olmaktadir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19548812A DE19548812A1 (de) | 1995-12-27 | 1995-12-27 | Verwendung von Inhibitoren des zellulären Na·+·/H·+·-Exchangers (NHE) zur Herstellung eines Medikaments zur Atemstimulation |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199801235T2 true TR199801235T2 (tr) | 1998-10-21 |
Family
ID=7781474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1998/01235T TR199801235T2 (tr) | 1995-12-27 | 1996-12-13 | Inhibitörlerin solunum stimülasyonuna yönelik ilaç üretiminde kullanimi. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0869779A1 (tr) |
KR (1) | KR19990076802A (tr) |
CN (1) | CN1207676A (tr) |
AU (1) | AU717247B2 (tr) |
BR (1) | BR9612287A (tr) |
CA (1) | CA2241531A1 (tr) |
CZ (1) | CZ202198DA3 (tr) |
DE (1) | DE19548812A1 (tr) |
HU (1) | HUP9900807A3 (tr) |
IL (1) | IL125114A0 (tr) |
MX (1) | MX9805141A (tr) |
NO (1) | NO982989L (tr) |
PL (1) | PL327693A1 (tr) |
SK (1) | SK88398A3 (tr) |
TR (1) | TR199801235T2 (tr) |
WO (1) | WO1997024113A1 (tr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9504537D0 (sv) * | 1995-12-19 | 1995-12-19 | Jan Hedner | Sätt att behandla och diagnosticera andningsstörningar under sömn och medel för utförande av sättet |
DE19945302A1 (de) * | 1999-09-22 | 2001-03-29 | Merck Patent Gmbh | Biphenylderivate als NHE-3-Inhibitoren |
DE10060292A1 (de) | 2000-12-05 | 2002-06-20 | Aventis Pharma Gmbh | Verwendung substituierter Benzimidazole zur Herstellung eines Medikaments zur Behandlung von Krankheiten, welche durch Inhibierung des Na+/H+-Austauschers beeinflusst werden können und sie enthaltendes Medikament |
DE10163239A1 (de) * | 2001-12-21 | 2003-07-10 | Aventis Pharma Gmbh | Substituierte Imidazolidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie enthaltendes Medikament |
WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
WO2010078449A2 (en) | 2008-12-31 | 2010-07-08 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
EP2887964B1 (en) | 2012-08-21 | 2019-07-03 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
SI2983667T1 (sl) | 2013-04-12 | 2019-09-30 | Ardelyx, Inc. | Spojine za vezavo NHE3 in metode za zaviranje transporta fosfata |
DK3173408T3 (en) | 2014-07-25 | 2019-03-04 | Taisho Pharmaceutical Co Ltd | PHENYLTETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL |
JP7292207B2 (ja) | 2017-01-09 | 2023-06-16 | アルデリックス, インコーポレイテッド | 消化管障害を処置するために有用な化合物 |
CA3049679A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Inhibitors of nhe-mediated antiport |
EA202090438A1 (ru) | 2017-08-04 | 2020-06-15 | Арделикс, Инк. | Производные глицерретиновой кислоты для лечения гиперкалиемии |
MX2021009491A (es) | 2019-02-07 | 2021-09-08 | Ardelyx Inc | Compuestos y metodos para tratar la hiperpotasemia. |
JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス, インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4325822A1 (de) * | 1993-07-31 | 1995-02-02 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
EP0639573A1 (de) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
DE4337609A1 (de) * | 1993-11-04 | 1995-05-11 | Boehringer Ingelheim Kg | Neue Pyrazincarboxamidderivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
DE4415873A1 (de) * | 1994-05-05 | 1995-11-09 | Hoechst Ag | Substituierte bizyklische Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1995
- 1995-12-27 DE DE19548812A patent/DE19548812A1/de not_active Withdrawn
-
1996
- 1996-12-13 CA CA002241531A patent/CA2241531A1/en not_active Abandoned
- 1996-12-13 KR KR1019980704927A patent/KR19990076802A/ko not_active Application Discontinuation
- 1996-12-13 IL IL12511496A patent/IL125114A0/xx unknown
- 1996-12-13 SK SK883-98A patent/SK88398A3/sk unknown
- 1996-12-13 PL PL96327693A patent/PL327693A1/xx unknown
- 1996-12-13 CN CN96199403A patent/CN1207676A/zh active Pending
- 1996-12-13 EP EP96943956A patent/EP0869779A1/de not_active Withdrawn
- 1996-12-13 BR BR9612287-0A patent/BR9612287A/pt unknown
- 1996-12-13 TR TR1998/01235T patent/TR199801235T2/tr unknown
- 1996-12-13 AU AU13720/97A patent/AU717247B2/en not_active Ceased
- 1996-12-13 WO PCT/EP1996/005614 patent/WO1997024113A1/de not_active Application Discontinuation
- 1996-12-13 HU HU9900807A patent/HUP9900807A3/hu unknown
-
1998
- 1998-06-24 MX MX9805141A patent/MX9805141A/es unknown
- 1998-06-26 NO NO982989A patent/NO982989L/no not_active Application Discontinuation
-
2021
- 2021-03-03 CZ CZ982021A patent/CZ202198DA3/cs unknown
Also Published As
Publication number | Publication date |
---|---|
DE19548812A1 (de) | 1997-07-03 |
MX9805141A (es) | 1998-10-31 |
WO1997024113A1 (de) | 1997-07-10 |
SK88398A3 (en) | 1999-03-12 |
EP0869779A1 (de) | 1998-10-14 |
CZ202198DA3 (cs) | 1998-11-11 |
IL125114A0 (en) | 1999-01-26 |
KR19990076802A (ko) | 1999-10-15 |
AU1372097A (en) | 1997-07-28 |
NO982989L (no) | 1998-08-06 |
CA2241531A1 (en) | 1997-07-10 |
AU717247B2 (en) | 2000-03-23 |
HUP9900807A3 (en) | 2000-11-28 |
NO982989D0 (no) | 1998-06-26 |
HUP9900807A2 (hu) | 1999-07-28 |
PL327693A1 (en) | 1998-12-21 |
CN1207676A (zh) | 1999-02-10 |
BR9612287A (pt) | 2005-05-24 |
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