TR199801091T2 - Üre ve üretan gruplari ihtiva eden lineer blok polimer lineer blok polimerlerin üretilmesine yönelik metod ve blok polimerlerin implant olarak kullanilmasi. - Google Patents

Üre ve üretan gruplari ihtiva eden lineer blok polimer lineer blok polimerlerin üretilmesine yönelik metod ve blok polimerlerin implant olarak kullanilmasi.

Info

Publication number
TR199801091T2
TR199801091T2 TR1998/01091T TR9801091T TR199801091T2 TR 199801091 T2 TR199801091 T2 TR 199801091T2 TR 1998/01091 T TR1998/01091 T TR 1998/01091T TR 9801091 T TR9801091 T TR 9801091T TR 199801091 T2 TR199801091 T2 TR 199801091T2
Authority
TR
Turkey
Prior art keywords
block polymers
implants
urethane groups
production
containing urea
Prior art date
Application number
TR1998/01091T
Other languages
English (en)
Inventor
Flod�N Per
Original Assignee
Artimplant Development Artdev Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Artimplant Development Artdev Ab filed Critical Artimplant Development Artdev Ab
Publication of TR199801091T2 publication Critical patent/TR199801091T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/67—Unsaturated compounds having active hydrogen
    • C08G18/675—Low-molecular-weight compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4236—Polycondensates having carboxylic or carbonic ester groups in the main chain containing only aliphatic groups
    • C08G18/4238—Polycondensates having carboxylic or carbonic ester groups in the main chain containing only aliphatic groups derived from dicarboxylic acids and dialcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/4269—Lactones
    • C08G18/4277—Caprolactone and/or substituted caprolactone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

Bu bulus insanlarda veya hayvanlarda bir implant olarak kullanilmaya (örnegin ligament olarak) özellikle uygun olan bir lineer blok polimer ile ilgilidir. Blok polimer üre ve üretan gruplari ihtiva eder ve moleküler agirligi da en az 10 4 Dalton tercihen de en az 10 5 Dalton'dur, ve de primer NH2 ve/veya OH uç gruplari içerir. Bir biyolojik ortamda bir implant olarak blok polimerin kullanilmasinin disinda bu bulus ayni zamanda bunun üretilmesine yönelik bir metodu da içerir, ve bu metod molekül basina iki izosiyanat uç grubunu havi bir prepolimerin, mol orani NH2/NCO 0.95 ila 1.05 olacak sekilde, bir alifatik veya aromatik diamin ile zincirinin uzatilmasiyla tanimlanir.
TR1998/01091T 1995-12-15 1996-11-25 Üre ve üretan gruplari ihtiva eden lineer blok polimer lineer blok polimerlerin üretilmesine yönelik metod ve blok polimerlerin implant olarak kullanilmasi. TR199801091T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9504495A SE505703C2 (sv) 1995-12-15 1995-12-15 Linjär blockpolymer innefattande urea- och uretangrupper, förfarande för framställning av linjära blockpolymerer samt användning av blockpolymererna som implantat

Publications (1)

Publication Number Publication Date
TR199801091T2 true TR199801091T2 (tr) 2001-12-21

Family

ID=20400606

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/01091T TR199801091T2 (tr) 1995-12-15 1996-11-25 Üre ve üretan gruplari ihtiva eden lineer blok polimer lineer blok polimerlerin üretilmesine yönelik metod ve blok polimerlerin implant olarak kullanilmasi.

Country Status (26)

Country Link
US (1) US6210441B1 (tr)
EP (1) EP0866816B1 (tr)
JP (1) JP4059524B2 (tr)
KR (1) KR20000064383A (tr)
CN (1) CN1152899C (tr)
AT (1) ATE201704T1 (tr)
AU (1) AU709440B2 (tr)
BR (1) BR9612032A (tr)
CA (1) CA2240061A1 (tr)
CZ (1) CZ179398A3 (tr)
DE (1) DE69613144T2 (tr)
DK (1) DK0866816T3 (tr)
ES (1) ES2159769T3 (tr)
GR (1) GR3036469T3 (tr)
HU (1) HUP9901201A3 (tr)
IL (1) IL124884A (tr)
NO (1) NO982703L (tr)
NZ (1) NZ324479A (tr)
PL (1) PL327246A1 (tr)
PT (1) PT866816E (tr)
RU (1) RU2189993C2 (tr)
SE (1) SE505703C2 (tr)
SI (1) SI0866816T1 (tr)
SK (1) SK79798A3 (tr)
TR (1) TR199801091T2 (tr)
WO (1) WO1997022643A1 (tr)

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SE513491C2 (sv) * 1998-12-15 2000-09-18 Artimplant Dev Artdev Ab Implantat för insättning i människor eller djur innefattande böjliga trådformiga element
SE514064C2 (sv) * 1999-02-02 2000-12-18 Artimplant Dev Artdev Ab Film för medicinsk användning bestående av linjära blockpolymerer av polyuretaner samt förfarande för framställning av en sådan film
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
AR032052A1 (es) * 2000-12-29 2003-10-22 Artimplant Ab Polimero lineal de bloques, procedimiento para su preparacion, su uso, implantes, material para relleno, composiciones farmaceuticas y material polimerico poroso que comprenden dicho polimero lineal de bloques
SE0101523L (sv) * 2000-12-29 2002-06-30 Artimplant Ab Linjär polymer
SE526106C2 (sv) * 2002-06-20 2005-07-05 Artimplant Ab Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
WO2004065450A2 (en) * 2003-01-16 2004-08-05 Carnegie Mellon University Biodegradable polyurethanes and use thereof
US8791073B2 (en) * 2004-05-14 2014-07-29 William Marsh Rice University Peptide-modified polyurethane compositions and associated methods
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
US20060153796A1 (en) * 2005-01-10 2006-07-13 Fitz Benjamin D Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant
US20070167617A1 (en) * 2006-01-17 2007-07-19 Fitz Benjamin D Method of making a diisocyanate terminated macromer
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US20070282011A1 (en) * 2006-05-09 2007-12-06 Medivas, Llc Biodegradable water soluble polymers
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
EP1985319B1 (en) * 2007-04-23 2012-06-13 Jointsphere B.V. Device for cartilage repair
EP2178944A1 (en) * 2007-07-24 2010-04-28 Medivas, LLC Biodegradable cationic polymer gene transfer compositions and methods of use
US8324292B2 (en) * 2008-02-29 2012-12-04 Ethicon, Inc. Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant
US8071663B2 (en) * 2008-02-29 2011-12-06 Ethicon, Inc. Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant
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Also Published As

Publication number Publication date
HUP9901201A2 (hu) 1999-07-28
IL124884A (en) 2002-03-10
CA2240061A1 (en) 1997-06-26
WO1997022643A1 (en) 1997-06-26
JP2000502142A (ja) 2000-02-22
CN1152899C (zh) 2004-06-09
SK79798A3 (en) 1999-03-12
NO982703D0 (no) 1998-06-11
NZ324479A (en) 1999-05-28
HUP9901201A3 (en) 2000-04-28
SE505703C2 (sv) 1997-09-29
EP0866816B1 (en) 2001-05-30
AU709440B2 (en) 1999-08-26
DE69613144T2 (de) 2001-11-29
SE9504495D0 (sv) 1995-12-15
CN1214057A (zh) 1999-04-14
AU1154797A (en) 1997-07-14
KR20000064383A (ko) 2000-11-06
SE9504495L (sv) 1997-06-16
PT866816E (pt) 2001-10-31
PL327246A1 (en) 1998-12-07
NO982703L (no) 1998-07-14
JP4059524B2 (ja) 2008-03-12
GR3036469T3 (en) 2001-11-30
EP0866816A1 (en) 1998-09-30
DE69613144D1 (de) 2001-07-05
US6210441B1 (en) 2001-04-03
BR9612032A (pt) 1999-12-28
CZ179398A3 (cs) 1998-11-11
ES2159769T3 (es) 2001-10-16
RU2189993C2 (ru) 2002-09-27
ATE201704T1 (de) 2001-06-15
SI0866816T1 (tr) 2001-10-31
DK0866816T3 (da) 2001-09-10
IL124884A0 (en) 1999-01-26

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