TR199800563T1 - Transdermal matris sistemi. - Google Patents

Transdermal matris sistemi.

Info

Publication number
TR199800563T1
TR199800563T1 TR1998/00563T TR9800563T TR199800563T1 TR 199800563 T1 TR199800563 T1 TR 199800563T1 TR 1998/00563 T TR1998/00563 T TR 1998/00563T TR 9800563 T TR9800563 T TR 9800563T TR 199800563 T1 TR199800563 T1 TR 199800563T1
Authority
TR
Turkey
Prior art keywords
parts
matrix system
transdermal matrix
matrix
transdermal
Prior art date
Application number
TR1998/00563T
Other languages
English (en)
Inventor
Christine Math Marie
Teillaud Eric
Bevan Bruno
Original Assignee
Laboratoires D'hygiene Et De Dietetique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires D'hygiene Et De Dietetique filed Critical Laboratoires D'hygiene Et De Dietetique
Publication of TR199800563T1 publication Critical patent/TR199800563T1/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Telephonic Communication Services (AREA)
  • Soy Sauces And Products Related Thereto (AREA)

Abstract

Hormonlarin perkutanöz yoldan uygulanmasi için bir tasiyici araç ve bir yapiskan matris içeren yeni bir transdermal matris sistemi açiklanmaktadir. Bu matris sunlari içermektedir: (a) agirlikça 39-61 kisim bir etilen/vinil asetat kopolimeri, (b) agirlikça 12-17 kisim 2-oktildodesil miristat, (c) agirlikça 5-17 kisim dietil ftalat, (d) agirlikça 10-16 kisim N-alkil-2 pirolidonlar arasindan seçilen bir bilesik, ki burada alkil grubu bir C4-15 grubudur, ve (e) agirlikça 1-12 kisim östrojenik ve progestojenik bilesenlerden olusan en az bir hormon. Bu transdermal matris sisteminin elde edilmesi için bir yöntem ve bu sistemin terapötik kullanimi da açiklanmaktadir.
TR1998/00563T 1995-09-27 1996-09-25 Transdermal matris sistemi. TR199800563T1 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9511326A FR2739032B1 (fr) 1995-09-27 1995-09-27 Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base d'eva, procede de preparation et utilisation en therapeutique

Publications (1)

Publication Number Publication Date
TR199800563T1 true TR199800563T1 (tr) 1998-06-22

Family

ID=9482961

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00563T TR199800563T1 (tr) 1995-09-27 1996-09-25 Transdermal matris sistemi.

Country Status (25)

Country Link
US (1) US6013276A (tr)
EP (1) EP0852492B1 (tr)
JP (1) JPH11514988A (tr)
KR (1) KR19990063732A (tr)
CN (1) CN1083259C (tr)
AT (1) ATE209031T1 (tr)
AU (1) AU702542B2 (tr)
BG (1) BG102322A (tr)
BR (1) BR9610665A (tr)
CA (1) CA2233162A1 (tr)
CZ (1) CZ95398A3 (tr)
DE (1) DE69617252T2 (tr)
DK (1) DK0852492T3 (tr)
EE (1) EE9800082A (tr)
ES (1) ES2170266T3 (tr)
FR (1) FR2739032B1 (tr)
HU (1) HUP9900375A3 (tr)
IL (1) IL123594A0 (tr)
NO (1) NO981252L (tr)
NZ (1) NZ319181A (tr)
PL (1) PL325644A1 (tr)
PT (1) PT852492E (tr)
SK (1) SK282613B6 (tr)
TR (1) TR199800563T1 (tr)
WO (1) WO1997011687A1 (tr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10211832A1 (de) * 2002-03-16 2003-10-02 Lohmann Therapie Syst Lts Hormonhaltiges transdermales therapeutisches System mit einem Wirkstoffreservoir auf der Basis von Vinylacetat-Vinylpyrrolidon-Copolymer mit verbesserter Kohäsion
US7833545B2 (en) 2003-04-29 2010-11-16 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
PT2782584T (pt) 2011-11-23 2021-09-02 Therapeuticsmd Inc Preparações e terapias de substituição para hormonoterapias naturais combinadas
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
MX2016014281A (es) 2014-05-22 2017-02-22 Therapeuticsmd Inc Formulaciones y terapias de reemplazo de combinación de hormonas naturales.
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3049628C2 (de) * 1980-12-31 1982-10-21 Basf Ag, 6700 Ludwigshafen Verfahren zur Überwachung des Entstehens und Fortschreitens von Rissen in Maschinenteilen und Bauteilen sowie eine Vorrichtung zur Durchführung des Verfahrens
JPS58189115A (ja) * 1982-04-30 1983-11-04 Kowa Co 外用剤
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
FR2612785A1 (fr) * 1987-03-25 1988-09-30 Lhd Lab Hygiene Dietetique Dispositif auto-adhesif d'administration d'un principe actif par voie percutanee
JPH03275619A (ja) * 1990-03-23 1991-12-06 Nitsusui Seiyaku Kk 外用剤組成物
US5286490A (en) * 1990-05-04 1994-02-15 Colgate-Palmolive Company Transdermal fluoride medication
US5122382A (en) * 1990-10-29 1992-06-16 Alza Corporation Transdermal contraceptive formulations, methods and devices
US5453279A (en) * 1992-04-21 1995-09-26 Tbs Laboratories, Inc. Enhancing transdermal absorption compositions; transdermal dosage form; and process
FR2717688B1 (fr) * 1994-03-28 1996-07-05 Lhd Lab Hygiene Dietetique Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base d'EVA.

Also Published As

Publication number Publication date
HUP9900375A3 (en) 1999-11-29
BG102322A (en) 1998-10-30
CN1197390A (zh) 1998-10-28
NO981252D0 (no) 1998-03-19
MX9802327A (es) 1998-08-30
AU702542B2 (en) 1999-02-25
CZ95398A3 (cs) 1998-07-15
PL325644A1 (en) 1998-08-03
HUP9900375A2 (hu) 1999-06-28
ES2170266T3 (es) 2002-08-01
CA2233162A1 (en) 1997-04-03
SK40698A3 (en) 1998-09-09
FR2739032B1 (fr) 1997-11-21
FR2739032A1 (fr) 1997-03-28
JPH11514988A (ja) 1999-12-21
EP0852492A1 (fr) 1998-07-15
PT852492E (pt) 2002-05-31
WO1997011687A1 (fr) 1997-04-03
NO981252L (no) 1998-03-19
NZ319181A (en) 1998-10-28
AU7134996A (en) 1997-04-17
US6013276A (en) 2000-01-11
KR19990063732A (ko) 1999-07-26
EE9800082A (et) 1998-10-15
DK0852492T3 (da) 2002-05-13
CN1083259C (zh) 2002-04-24
BR9610665A (pt) 1999-07-13
DE69617252D1 (de) 2002-01-03
SK282613B6 (sk) 2002-10-08
IL123594A0 (en) 1998-10-30
DE69617252T2 (de) 2002-07-25
ATE209031T1 (de) 2001-12-15
EP0852492B1 (fr) 2001-11-21

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