TR199501688A2 - 6-£triazolil£3-(trifluorometil)fenil|metil|-2-kuinolinonlar ve kuinolinetionlar. - Google Patents
6-£triazolil£3-(trifluorometil)fenil|metil|-2-kuinolinonlar ve kuinolinetionlar.Info
- Publication number
- TR199501688A2 TR199501688A2 TR95/01688A TR9501688A TR199501688A2 TR 199501688 A2 TR199501688 A2 TR 199501688A2 TR 95/01688 A TR95/01688 A TR 95/01688A TR 9501688 A TR9501688 A TR 9501688A TR 199501688 A2 TR199501688 A2 TR 199501688A2
- Authority
- TR
- Turkey
- Prior art keywords
- quinolinetions
- quinolinones
- triazolyl
- trifluoromethyl
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94203773 | 1994-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199501688A2 true TR199501688A2 (tr) | 1996-07-21 |
Family
ID=8217501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR95/01688A TR199501688A2 (tr) | 1994-12-28 | 1995-12-27 | 6-£triazolil£3-(trifluorometil)fenil|metil|-2-kuinolinonlar ve kuinolinetionlar. |
Country Status (25)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW591030B (en) | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| JP2002518387A (ja) * | 1998-06-16 | 2002-06-25 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | イミダゾリル誘導体 |
| US6420555B1 (en) | 1998-06-16 | 2002-07-16 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Imidazolyl derivatives |
| EP1420015A1 (en) * | 1999-06-11 | 2004-05-19 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Imidazolyl derivatives |
| JP4348080B2 (ja) * | 2000-11-21 | 2009-10-21 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ファルネシルトランスフェラーゼを阻害するベンゾ複素環誘導体 |
| DK1339407T3 (da) * | 2000-11-28 | 2006-08-14 | Janssen Pharmaceutica Nv | Farnesylproteintransferaseinhibitorer til behandling af inflammatorisk tarmsygdom |
| ES2263684T3 (es) * | 2000-12-27 | 2006-12-16 | Janssen Pharmaceutica N.V. | Derivados de 4-heterociclil-quinolina y -quinazolina que inhiben la farnesil transferasa. |
| ES2260316T3 (es) * | 2000-12-27 | 2006-11-01 | Janssen Pharmaceutica N.V. | Derivados de quinazolina y quinolina 4-sustituidos que inhiben la farnesil transferasa. |
| US8232402B2 (en) * | 2008-03-12 | 2012-07-31 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7908031A (nl) * | 1979-11-01 | 1981-06-01 | Acf Chemiefarma Nv | Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen. |
| US4792561A (en) * | 1986-05-29 | 1988-12-20 | Syntex (U.S.A.) Inc. | Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors |
| NZ221729A (en) * | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
| US4859684A (en) * | 1986-09-15 | 1989-08-22 | Janssen Pharmaceutica N.V. | (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders |
| EP0355583B1 (en) * | 1988-08-10 | 1995-01-25 | Otsuka Pharmaceutical Co., Ltd. | Cardiotonics |
| US5157046A (en) * | 1988-11-29 | 1992-10-20 | Janssen Pharmaceutica N.V. | Method of treating epithelial disorders |
| CA2002864C (en) * | 1988-11-29 | 1999-11-16 | Eddy J. E. Freyne | (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives |
| GB8827822D0 (en) * | 1988-11-29 | 1988-12-29 | Janssen Pharmaceutica Nv | (1h-azol-1-ylmethyl)substituted quinoline derivatives |
| US5185346A (en) * | 1988-11-29 | 1993-02-09 | Hanssen Pharmaceutica | (1H-azol-1-ylmethyl)substituted quinoline derivatives |
| CA2002859C (en) * | 1988-11-29 | 1998-12-29 | Jean P. F. Van Wauwe | Method of treating epithelial disorders |
| CA2015267A1 (en) * | 1989-05-26 | 1990-11-26 | Rainer Seele | 8-azolylmethylquinolines |
-
1995
- 1995-12-20 TW TW084113605A patent/TW316902B/zh active
- 1995-12-21 PT PT95943237T patent/PT800524E/pt unknown
- 1995-12-21 EP EP95943237A patent/EP0800524B1/en not_active Expired - Lifetime
- 1995-12-21 WO PCT/EP1995/005173 patent/WO1996020200A1/en not_active Application Discontinuation
- 1995-12-21 DK DK95943237T patent/DK0800524T3/da active
- 1995-12-21 CA CA002207268A patent/CA2207268A1/en not_active Abandoned
- 1995-12-21 US US08/860,239 patent/US5922734A/en not_active Expired - Fee Related
- 1995-12-21 AU AU44362/96A patent/AU698199B2/en not_active Ceased
- 1995-12-21 FI FI972794A patent/FI972794A0/fi unknown
- 1995-12-21 CN CN95197162A patent/CN1085668C/zh not_active Expired - Fee Related
- 1995-12-21 ES ES95943237T patent/ES2166838T3/es not_active Expired - Lifetime
- 1995-12-21 DE DE69523629T patent/DE69523629T2/de not_active Expired - Fee Related
- 1995-12-21 AT AT95943237T patent/ATE207924T1/de not_active IP Right Cessation
- 1995-12-21 BR BR9510504A patent/BR9510504A/pt not_active Application Discontinuation
- 1995-12-21 JP JP8520222A patent/JPH10511654A/ja active Pending
- 1995-12-21 RU RU97112898/04A patent/RU2165419C2/ru not_active IP Right Cessation
- 1995-12-21 NZ NZ298789A patent/NZ298789A/xx unknown
- 1995-12-21 PL PL95321041A patent/PL182956B1/pl unknown
- 1995-12-22 HR HR94203773.0A patent/HRP950616A2/hr not_active Application Discontinuation
- 1995-12-27 ZA ZA9510989A patent/ZA9510989B/xx unknown
- 1995-12-27 AR ARP950100795A patent/AR002264A1/es unknown
- 1995-12-27 IL IL11657795A patent/IL116577A/xx not_active IP Right Cessation
- 1995-12-27 TR TR95/01688A patent/TR199501688A2/xx unknown
- 1995-12-28 MY MYPI95004141A patent/MY131690A/en unknown
-
1997
- 1997-06-27 NO NO19973029A patent/NO311220B1/no unknown
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