TNSN07138A1 - Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents - Google Patents

Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents

Info

Publication number
TNSN07138A1
TNSN07138A1 TNP2007000138A TNSN07138A TNSN07138A1 TN SN07138 A1 TNSN07138 A1 TN SN07138A1 TN P2007000138 A TNP2007000138 A TN P2007000138A TN SN07138 A TNSN07138 A TN SN07138A TN SN07138 A1 TNSN07138 A1 TN SN07138A1
Authority
TN
Tunisia
Prior art keywords
benzisoxazoles
benzisothiazoles
indazoles
estrogenic agents
estrogenic
Prior art date
Application number
TNP2007000138A
Other languages
English (en)
Inventor
Benoit Rondot
Jean Lafay
Paul Bonnet
Thierry Clerc
Igor Duc
Eric Duranti
Francois Puccio
Jacqueline Shields
Christian Blot
Philippe Maillos
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Publication of TNSN07138A1 publication Critical patent/TNSN07138A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
TNP2007000138A 2004-10-14 2007-04-13 Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents TNSN07138A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04292439A EP1647549A1 (fr) 2004-10-14 2004-10-14 Indazoles, benzisoxazoles et benzisothiazoles en tant qu'agents oestrogéniques
PCT/EP2005/055262 WO2006040351A1 (fr) 2004-10-14 2005-10-14 Indazoles, benzisoxazoles et benzisothiazoles et leur utilisation en tant qu'agents oestrogeniques

Publications (1)

Publication Number Publication Date
TNSN07138A1 true TNSN07138A1 (en) 2008-11-21

Family

ID=34931452

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2007000138A TNSN07138A1 (en) 2004-10-14 2007-04-13 Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents

Country Status (24)

Country Link
US (2) US7977364B2 (fr)
EP (2) EP1647549A1 (fr)
JP (1) JP5047801B2 (fr)
KR (1) KR20070109976A (fr)
CN (1) CN101080395B (fr)
AP (1) AP2007003960A0 (fr)
AR (1) AR051457A1 (fr)
AT (1) ATE512952T1 (fr)
AU (1) AU2005293509B2 (fr)
BR (1) BRPI0516851A (fr)
CA (1) CA2582180C (fr)
ES (1) ES2368203T3 (fr)
IL (1) IL182047A (fr)
MA (1) MA28928B1 (fr)
MX (1) MX2007004372A (fr)
NO (1) NO20071922L (fr)
NZ (1) NZ554279A (fr)
RU (1) RU2402536C2 (fr)
SG (1) SG158886A1 (fr)
TN (1) TNSN07138A1 (fr)
TW (1) TW200619202A (fr)
UA (1) UA90280C2 (fr)
WO (1) WO2006040351A1 (fr)
ZA (1) ZA200702690B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1647549A1 (fr) * 2004-10-14 2006-04-19 Laboratoire Theramex Indazoles, benzisoxazoles et benzisothiazoles en tant qu'agents oestrogéniques
JP4965270B2 (ja) * 2007-01-16 2012-07-04 出光興産株式会社 アダマンチルカルボニル基含有芳香族ジオール、その誘導体及びそれらの製造方法
FR2913019A1 (fr) * 2007-02-23 2008-08-29 Cerep Sa Composes heterocycliques comme agents anti-neoplasiques ou inhibiteurs de proliferation cellulaire
GB0704407D0 (en) 2007-03-07 2007-04-18 Glaxo Group Ltd Compounds
GB0803017D0 (en) * 2008-02-19 2008-03-26 Glaxo Group Ltd Compounds
JP6068451B2 (ja) * 2011-05-17 2017-01-25 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・カリフオルニア キナーゼ阻害剤
US20150018398A1 (en) * 2013-07-15 2015-01-15 The Regents Of The University Of California Methods of using estrogen receptor-beta ligands as radiation mitigators
DE102015012050A1 (de) * 2015-09-15 2017-03-16 Merck Patent Gmbh Verbindungen als ASIC-Inhibitoren und deren Verwendungen
CN109111407A (zh) * 2017-06-23 2019-01-01 江苏恩华药业股份有限公司 一种苯并异恶唑类化合物衍生物及其应用
BR112020002265A2 (pt) 2017-08-01 2020-07-28 Theravance Biopharma R&D Ip, Llc compostos pirazólicos e triazólicos bicíclicos como inibidores de jak quiinase
CN110117278B (zh) * 2018-02-07 2022-07-19 石家庄以岭药业股份有限公司 烷氧基苯并五元(六元)杂环胺类化合物及其药物用途
WO2020154350A1 (fr) 2019-01-23 2020-07-30 Theravance Biopharma R&D Ip, Llc Imidazo[1,5-a]pyridine,1,2,4-triazolo[4,3-a]pyridine et imidazo[1,5-a]pyrazine utilisées en tant qu'inhibiteurs de jak

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1406882A (en) * 1972-04-28 1975-09-17 Leo Pharm Prod Ltd Benzoic acid derivatives and benzisptjoaup'e 1.1 dopxode derovatoves
JPS50157363A (fr) * 1974-06-06 1975-12-19
US4166452A (en) * 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) * 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) * 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US6090836A (en) * 1996-02-02 2000-07-18 Merck & Co., Inc. Benzisoxazole-derived antidiabetic compounds
AU708055B2 (en) * 1996-02-02 1999-07-29 Merck & Co., Inc. Heterocyclic derivatives as antidiabetic and antiobesity agents
US6008237A (en) * 1997-12-19 1999-12-28 Merck & Co., Inc. Arylthiazolidinedione derivatives
US6399640B1 (en) * 1999-06-18 2002-06-04 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
PE20010306A1 (es) * 1999-07-02 2001-03-29 Agouron Pharma Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
GB0002666D0 (en) * 2000-02-04 2000-03-29 Univ London Blockade of voltage dependent sodium channels
JP2001288175A (ja) * 2000-04-06 2001-10-16 Nippon Soda Co Ltd ヒドロキシベンゾイソオキサゾール化合物、製造方法、製造中間体、抗真菌薬および農園芸用殺菌剤
US6897231B2 (en) * 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
DE10046029A1 (de) * 2000-09-18 2002-03-28 Bayer Ag Indazole
BR0115075A (pt) * 2000-11-02 2003-07-29 Hoffmann La Roche Benzo'b!tiofenos e benzo'd!isotiazóis para baixamento de colesterol
US6608409B2 (en) * 2001-05-15 2003-08-19 General Electric Company High temperature super-conducting rotor having a vacuum vessel and electromagnetic shield and an assembly method
CA2447156A1 (fr) * 2001-06-01 2002-12-12 Alcon, Inc. Indazoles et indoles nouveaux fusionnes et leur utilisation dans le traitement de glaucomes
US7199147B2 (en) * 2001-06-12 2007-04-03 Dainippon Sumitomo Pharma Co., Ltd. Rho kinase inhibitors
ES2357502T3 (es) * 2001-09-26 2011-04-27 Pfizer Italia S.R.L. Derivados de aminoindazol activos como inhibidores de quinasa, procedimiento para su preparación y composiciones farmaceuticas que los contienen.
US6960607B2 (en) * 2001-12-13 2005-11-01 Wyeth Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents
US6884814B2 (en) * 2001-12-13 2005-04-26 Wyeth Phenyl benzisoxazoles as estrogenic agents
US7104676B2 (en) * 2002-04-15 2006-09-12 K.W. Muth Company, Inc. Signaling assembly
US7429609B2 (en) * 2002-05-31 2008-09-30 Eisai R & D Management Co., Ltd. Pyrazole compound and medicinal composition containing the same
TW200400177A (en) * 2002-06-04 2004-01-01 Wyeth Corp 1-(Aminoalkyl)-3-sulfonylindole and-indazole derivatives as 5-hydroxytryptamine-6 ligands
TW200401641A (en) * 2002-07-18 2004-02-01 Wyeth Corp 1-Heterocyclylalkyl-3-sulfonylindole or-indazole derivatives as 5-hydroxytryptamine-6 ligands
PL374946A1 (en) 2002-09-05 2005-11-14 Aventis Pharma S.A. Novel aminoindazole derivatives as medicines and pharmaceutical compositions containing same
TW200409759A (en) * 2002-09-25 2004-06-16 Wyeth Corp Substituted 4-(indazol-3-yl)phenols
JP2006510742A (ja) 2002-11-08 2006-03-30 メルク　エンド　カムパニー　インコーポレーテッド 高眼圧治療用眼科組成物
US7196082B2 (en) * 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
CA2507948A1 (fr) 2002-12-12 2004-07-29 Aventis Pharma S.A. Derives d'aminoindazoles et leur utilisation comme inhibiteurs de kinases
US7135575B2 (en) * 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
MXPA05009459A (es) * 2003-03-03 2006-05-17 Array Biopharma Inc Inhibidores de p38 y sus metodos de uso.
US7592494B2 (en) * 2003-07-25 2009-09-22 Honeywell International Inc. Process for the manufacture of 1,3,3,3-tetrafluoropropene
DE10339719A1 (de) * 2003-08-28 2005-03-24 BSH Bosch und Siemens Hausgeräte GmbH Blähkörper zum Trocknen und/oder Glätten von Kleidungsstücken
FR2864084B1 (fr) * 2003-12-17 2006-02-10 Aventis Pharma Sa Nouveaux derives organophosphores des indazoles et leur utilisation comme medicaments
KR20060114022A (ko) * 2004-02-27 2006-11-03 에프. 호프만-라 로슈 아게 인다졸 유도체 및 그들을 함유하는 약학 조성물
MX2007001132A (es) * 2004-07-27 2007-03-15 Novartis Ag Inhibidores de hsp90.
EP1647549A1 (fr) * 2004-10-14 2006-04-19 Laboratoire Theramex Indazoles, benzisoxazoles et benzisothiazoles en tant qu'agents oestrogéniques

Also Published As

Publication number Publication date
EP1812404A1 (fr) 2007-08-01
ES2368203T3 (es) 2011-11-15
NZ554279A (en) 2010-09-30
US8173679B2 (en) 2012-05-08
CN101080395A (zh) 2007-11-28
IL182047A0 (en) 2007-07-24
UA90280C2 (ru) 2010-04-26
AR051457A1 (es) 2007-01-17
BRPI0516851A (pt) 2008-09-23
ATE512952T1 (de) 2011-07-15
MX2007004372A (es) 2007-06-07
MA28928B1 (fr) 2007-10-01
AP2007003960A0 (en) 2007-04-30
TW200619202A (en) 2006-06-16
AU2005293509A1 (en) 2006-04-20
WO2006040351A1 (fr) 2006-04-20
EP1647549A1 (fr) 2006-04-19
US20110237624A1 (en) 2011-09-29
NO20071922L (no) 2007-07-06
US20090023779A1 (en) 2009-01-22
US7977364B2 (en) 2011-07-12
IL182047A (en) 2013-03-24
RU2402536C2 (ru) 2010-10-27
CA2582180C (fr) 2013-04-30
CN101080395B (zh) 2011-08-17
JP5047801B2 (ja) 2012-10-10
CA2582180A1 (fr) 2006-04-20
RU2007117714A (ru) 2008-11-20
JP2008516929A (ja) 2008-05-22
KR20070109976A (ko) 2007-11-15
SG158886A1 (en) 2010-02-26
EP1812404B1 (fr) 2011-06-15
ZA200702690B (en) 2008-10-29
AU2005293509B2 (en) 2012-01-12

Similar Documents

Publication Publication Date Title
TNSN07138A1 (en) Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents
MXPA05011679A (es) Derivados de hidroxibifenilcarbaldehido oxima y su uso como agentes estrogenicos.
MXPA06001592A (es) Derivados de (4-hidroxifenil)-1h-indol-3-carbaldehido oxima como agentes estrogenicos.
MXPA05012249A (es) Derivados de arilcarbaldehido oxima y su uso como agentes estrogenicos.
TW200510319A (en) Phenyl quinolines and their use as estrogenic agents
MX2007011023A (es) 2-(4-oxo-4h-quinazolin-3-il) acetamidas y su uso como antagonistas de vasopresin v3.
UA83620C2 (ru) Замещенные бензоксазолы и их аналоги как эстрогенные агенты
DE60335869D1 (de) 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren
WO2005037199A3 (fr) Derives de pyrazole utilises comme modulateurs du recepteur de cannabinoide
TNSN08311A1 (en) Indole sulfonamide modulators of progesterone receptors
TW200612925A (en) Prodrug substituted benzoxazoles as estrogenic agents
MX2009003227A (es) Moduladores de los receptores de glutamato metabotropicos 5(mglur5).
MX2009010363A (es) Compuestos de 1,3-tiazol-2(3h)-ilideno como ligandos del receptor canabinoide.
HK1154777A1 (en) Lipoprotein lipase-activating compositions comprising benzene derivatives
TW200740781A (en) Novel compounds
CR10603A (es) Derivados de 5,6-bisaril-2-piridin-carboxamida, su preparacion y su aplicacion en terapeutica como antagonistas de los receptores de urotensina ii
MX2007010572A (es) Compuestos de cinolina y su uso como moduladores de receptor x de higado.
SG151306A1 (en) Novel benzothiazoles and the use thereof as medicaments
MX2010009927A (es) Derivados de espiroindolinona.
ATE399775T1 (de) Triphenylethyleneverbindungen als selektive modulatoren des östrogenrezeptors
NO20065885L (no) Steroide prolegemidler med androgen virkning
MXPA05010651A (es) Compuestos de pirazol.
HK1101667A1 (en) 5-iodotetrazoles
AR045668A1 (es) Mezcla de agentes tensioactivos y solventes
WO2008019030A3 (fr) Composés d'azole modifiés en tant qu'agents anti-infectieux