SV2009003342A - Nuevo procedimiento de sintesis de la agomelatina - Google Patents
Nuevo procedimiento de sintesis de la agomelatinaInfo
- Publication number
- SV2009003342A SV2009003342A SV2009003342A SV2009003342A SV2009003342A SV 2009003342 A SV2009003342 A SV 2009003342A SV 2009003342 A SV2009003342 A SV 2009003342A SV 2009003342 A SV2009003342 A SV 2009003342A SV 2009003342 A SV2009003342 A SV 2009003342A
- Authority
- SV
- El Salvador
- Prior art keywords
- synthesis procedure
- new
- agomelatine synthesis
- new agomelatine
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/48—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/08—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDIMIENTO DE SÍNTESIS INDUSTRIAL DEL COMPUESTO DE FÓRMULA (I): (VER FORMULA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0804463A FR2934857B1 (fr) | 2008-08-05 | 2008-08-05 | Nouveau procede de synthese de l'agomelatine |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2009003342A true SV2009003342A (es) | 2010-02-01 |
Family
ID=40404415
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV2009003342A SV2009003342A (es) | 2008-08-05 | 2009-07-29 | Nuevo procedimiento de sintesis de la agomelatina |
Country Status (45)
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2580183B1 (en) | 2010-06-10 | 2014-07-23 | Gador S.A. | New process for the preparation of n-[2-(7-methoxy-1-naphthyl)-ethyl]acetamide |
CN102229541A (zh) * | 2010-09-17 | 2011-11-02 | 福建广生堂药业有限公司 | 阿戈美拉汀n-[2-(7-甲氧基萘-1-基)乙基]乙酰胺的制备方法 |
CN102206170A (zh) * | 2011-03-18 | 2011-10-05 | 青岛黄海制药有限责任公司 | 一种制备阿戈美拉汀的方法 |
WO2013054273A2 (en) | 2011-10-11 | 2013-04-18 | Ranbaxy Laboratories Limited | Process for the preparation of agomelatine |
WO2013080095A1 (en) | 2011-12-01 | 2013-06-06 | Ranbaxy Laboratories Limited | Process for the preparation of agomelatine |
ITMI20121444A1 (it) | 2012-08-27 | 2014-02-28 | Procos Spa | Processo per la produzione di agomelatine |
CN102942501B (zh) * | 2012-12-10 | 2015-08-19 | 天津泰普药品科技发展有限公司 | 一种氢化制备阿戈美拉汀的生产方法 |
CN104130154A (zh) * | 2013-05-03 | 2014-11-05 | 郭炳华 | 一种制备高纯度阿戈美拉汀的方法 |
US9781669B2 (en) | 2013-09-20 | 2017-10-03 | Telefonaktiebolaget Lm Ericsson (Publ) | Statistics-assisted sCell selection |
US9756532B2 (en) | 2013-09-20 | 2017-09-05 | Telefonaktiebolaget L M Ericsson (Publ) | Carrier aggregation sCell selection for LTE-A |
FR3014437B1 (fr) * | 2013-12-05 | 2016-12-23 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
US10149214B2 (en) | 2014-02-03 | 2018-12-04 | Telefonaktiebolaget Lm Ericsson (Publ) | Secondary cell selection based on geographic signatures |
CN104557591B (zh) * | 2014-12-26 | 2016-09-07 | 扬子江药业集团四川海蓉药业有限公司 | 一种制备阿戈美拉汀乙酰二胺的方法 |
JP6158255B2 (ja) * | 2015-07-13 | 2017-07-05 | 株式会社三共 | 遊技機 |
CN107085044A (zh) * | 2017-03-27 | 2017-08-22 | 万全万特制药(厦门)有限公司 | 气相色谱法分离检测阿戈美拉汀中间体有关物质的方法 |
CN107151221A (zh) * | 2017-06-19 | 2017-09-12 | 太仓卡斯特姆新材料有限公司 | 一种制备阿戈美拉汀重要中间体7‑甲氧基萘乙腈的方法 |
CN107353229B (zh) * | 2017-08-08 | 2019-04-30 | 许昌恒生制药有限公司 | 一种阿戈美拉汀中间体的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1141276A (fr) * | 1955-02-14 | 1957-08-29 | Geigy Ag J R | Procédé de préparation de l'hexahydro-benzylamine |
US3062869A (en) * | 1958-11-07 | 1962-11-06 | Fmc Corp | Reduction of nitriles |
ES2145920T3 (es) * | 1994-09-06 | 2000-07-16 | Shionogi & Co | Procedimiento de produccion de derivado de alcoxiiminoacetamida. |
FR2773798B1 (fr) * | 1998-01-16 | 2001-02-02 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2866335B1 (fr) * | 2004-02-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
-
2008
- 2008-08-05 FR FR0804463A patent/FR2934857B1/fr not_active Expired - Fee Related
-
2009
- 2009-07-23 SG SG200904971-9A patent/SG158829A1/en unknown
- 2009-07-23 PE PE2009000982A patent/PE20100261A1/es active IP Right Grant
- 2009-07-24 CR CR10955A patent/CR10955A/es unknown
- 2009-07-27 AP AP2009004935A patent/AP2009004935A0/xx unknown
- 2009-07-27 AU AU2009203052A patent/AU2009203052B2/en not_active Ceased
- 2009-07-28 UY UY0001032013A patent/UY32013A/es not_active Application Discontinuation
- 2009-07-28 IL IL200127A patent/IL200127A/en not_active IP Right Cessation
- 2009-07-29 SV SV2009003342A patent/SV2009003342A/es active IP Right Grant
- 2009-07-29 MY MYPI20093145A patent/MY162033A/en unknown
- 2009-07-29 MX MX2009008047A patent/MX2009008047A/es active IP Right Grant
- 2009-07-30 ZA ZA200905333A patent/ZA200905333B/en unknown
- 2009-07-30 NI NI200900151A patent/NI200900151A/es unknown
- 2009-07-31 GT GT200900216A patent/GT200900216A/es unknown
- 2009-07-31 CO CO09080222A patent/CO6120162A1/es not_active Application Discontinuation
- 2009-07-31 EC EC2009009550A patent/ECSP099550A/es unknown
- 2009-07-31 MA MA32131A patent/MA31224B1/fr unknown
- 2009-08-02 SA SA109300497A patent/SA109300497B1/ar unknown
- 2009-08-02 JO JO2009285A patent/JO2816B1/en active
- 2009-08-03 US US12/462,363 patent/US8329947B2/en active Active
- 2009-08-03 GE GEAP200911401A patent/GEP20115345B/en unknown
- 2009-08-03 CL CL2009001684A patent/CL2009001684A1/es unknown
- 2009-08-03 NZ NZ578827A patent/NZ578827A/en not_active IP Right Cessation
- 2009-08-03 CA CA2674901A patent/CA2674901C/fr active Active
- 2009-08-04 ES ES09290605T patent/ES2401534T3/es active Active
- 2009-08-04 BR BRPI0902948-6A patent/BRPI0902948A2/pt not_active Application Discontinuation
- 2009-08-04 PL PL09290605T patent/PL2151427T3/pl unknown
- 2009-08-04 UA UAA200908226A patent/UA102817C2/ru unknown
- 2009-08-04 EA EA200900945A patent/EA015545B1/ru unknown
- 2009-08-04 RS RS20130056A patent/RS52644B/en unknown
- 2009-08-04 EP EP09290605A patent/EP2151427B1/fr active Active
- 2009-08-04 ME MEP-2013-153A patent/ME02073B/me unknown
- 2009-08-04 SI SI200930500T patent/SI2151427T1/sl unknown
- 2009-08-04 CU CU20090139A patent/CU23861B1/es active IP Right Grant
- 2009-08-04 DK DK09290605.6T patent/DK2151427T3/da active
- 2009-08-04 PT PT92906056T patent/PT2151427E/pt unknown
- 2009-08-04 AR ARP090102982A patent/AR075644A1/es unknown
- 2009-08-04 TW TW098126196A patent/TWI386385B/zh not_active IP Right Cessation
- 2009-08-04 WO PCT/FR2009/000971 patent/WO2010015744A1/fr active Application Filing
- 2009-08-04 KR KR1020090071641A patent/KR101135336B1/ko active IP Right Grant
- 2009-08-05 JP JP2009182088A patent/JP5112399B2/ja not_active Expired - Fee Related
- 2009-08-05 CN CN200910160308.1A patent/CN101643433B/zh not_active Expired - Fee Related
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2010
- 2010-08-09 HK HK10107581.8A patent/HK1141006A1/xx not_active IP Right Cessation
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2013
- 2013-02-25 CY CY20131100172T patent/CY1113716T1/el unknown
- 2013-03-08 HR HRP20130201AT patent/HRP20130201T1/hr unknown
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Legal Events
Date | Code | Title | Description |
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FG | Grant |