SV2002000517A - Formas/hidratos polimorficas/os de dihidrocloruro den-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilpropoxi)-quinazolin-6-il]-acrilamida,procedimientos para su obtencion y su uso en la preparacion de medicamentos que tienen una accion de inhibicio - Google Patents

Formas/hidratos polimorficas/os de dihidrocloruro den-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilpropoxi)-quinazolin-6-il]-acrilamida,procedimientos para su obtencion y su uso en la preparacion de medicamentos que tienen una accion de inhibicio

Info

Publication number
SV2002000517A
SV2002000517A SV2001000517A SV2001000517A SV2002000517A SV 2002000517 A SV2002000517 A SV 2002000517A SV 2001000517 A SV2001000517 A SV 2001000517A SV 2001000517 A SV2001000517 A SV 2001000517A SV 2002000517 A SV2002000517 A SV 2002000517A
Authority
SV
El Salvador
Prior art keywords
obtaining
ilpropoxi
fluorphenylamine
morfolin
quinazolin
Prior art date
Application number
SV2001000517A
Other languages
English (en)
Inventor
Hubert Barth
Klaus Steiner
Simon Schneider
Dietmar Huls
Andreas Muhlenfeld
Manfred Westermayer
Original Assignee
Godecke Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Godecke Gmbh filed Critical Godecke Gmbh
Publication of SV2002000517A publication Critical patent/SV2002000517A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

SE DESCRIBEN FORMAS/HIDRATOS POLIMORFICAS/OS DE DIHIDROCLORURO DE N-[4-(3-CLORO-4-FLUORFENILAMINO)-7-(3-MORFOLIN-4-ILPROPOXI)-QUINAZOLIN-6-IL]-ACRILAMIDA, PROCEDIMIENTOS PARA SU PREPARACION Y SU USO EN LA OBTENCION DE MEDICAMENTOS QUE PRESENTAN UNA ACCION DE INHIBICION IRREVERSIBLE DE TIROSINA QUINASA
SV2001000517A 2000-06-30 2001-06-29 Formas/hidratos polimorficas/os de dihidrocloruro den-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilpropoxi)-quinazolin-6-il]-acrilamida,procedimientos para su obtencion y su uso en la preparacion de medicamentos que tienen una accion de inhibicio SV2002000517A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10031971A DE10031971A1 (de) 2000-06-30 2000-06-30 Polymorphe Formen/Hydrate von N-[4-(3-Chlor-4-fluor-phenylamino)-7-(3-morpholin-4-yl-propoxy)-chinazolin-6-yl]-acrylamid Dihydrochlorid, Verfahren zu ihrer Herstellung sowie die Verwendung derselben zur Herstellung von Medikamenten mit irreversibler Tyrosinkinasehemmwirkung

Publications (1)

Publication Number Publication Date
SV2002000517A true SV2002000517A (es) 2002-07-03

Family

ID=7647397

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2001000517A SV2002000517A (es) 2000-06-30 2001-06-29 Formas/hidratos polimorficas/os de dihidrocloruro den-[4-(3-cloro-4-fluorfenilamino)-7-(3-morfolin-4-ilpropoxi)-quinazolin-6-il]-acrilamida,procedimientos para su obtencion y su uso en la preparacion de medicamentos que tienen una accion de inhibicio

Country Status (39)

Country Link
US (1) US20040034022A1 (es)
EP (1) EP1299363A1 (es)
JP (1) JP2004501902A (es)
KR (1) KR20030014403A (es)
CN (1) CN1438994A (es)
AP (1) AP2002002694A0 (es)
AR (1) AR031854A1 (es)
AU (1) AU2001283861A1 (es)
BG (1) BG107352A (es)
BR (1) BR0112082A (es)
CA (1) CA2412535A1 (es)
CZ (1) CZ20024037A3 (es)
DE (1) DE10031971A1 (es)
DZ (1) DZ3342A1 (es)
EA (1) EA005294B1 (es)
EC (1) ECSP024413A (es)
EE (1) EE200200714A (es)
GT (1) GT200100124A (es)
HN (1) HN2001000134A (es)
HR (1) HRP20021019A2 (es)
HU (1) HUP0300900A3 (es)
IL (1) IL152419A0 (es)
IS (1) IS6596A (es)
MA (1) MA26924A1 (es)
MX (1) MXPA03000101A (es)
NO (1) NO20026193L (es)
NZ (1) NZ522001A (es)
OA (1) OA12301A (es)
PA (1) PA8520801A1 (es)
PE (1) PE20020116A1 (es)
PL (1) PL365127A1 (es)
SK (1) SK17642002A3 (es)
SV (1) SV2002000517A (es)
TN (1) TNSN01090A1 (es)
UA (1) UA73588C2 (es)
UY (1) UY26803A1 (es)
WO (1) WO2002000630A1 (es)
YU (1) YU99802A (es)
ZA (1) ZA200209717B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA85706C2 (en) * 2004-05-06 2009-02-25 Уорнер-Ламберт Компани Ллси 4-phenylaminoquinazolin-6-yl amides
DE102006000122A1 (de) * 2006-03-17 2007-09-20 Aug. Winkhaus Gmbh & Co. Kg Schlüssel für einen Schließzylinder und Schließzylinder für einen solchen Schlüssel
US10633364B2 (en) * 2015-12-25 2020-04-28 Xuanzhu Pharma Co., Ltd. Crystals of quinazoline derivative and preparation method therefor
JP6674027B2 (ja) * 2015-12-25 2020-04-01 シュアンチュー ファーマ カンパニー，リミティド キナゾリン誘導体の結晶及びその調製方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL126351A0 (en) * 1996-04-12 1999-05-09 Warner Lambert Co Irreversible inhibitors of tyrosine kinases
NZ527718A (en) * 1998-11-19 2004-11-26 Warner Lambert Co N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, an irreversible inhibitor of tyrosine kinases

Also Published As

Publication number Publication date
IS6596A (is) 2002-10-28
NO20026193L (no) 2003-01-27
EA005294B1 (ru) 2004-12-30
TNSN01090A1 (fr) 2005-11-10
IL152419A0 (en) 2003-05-29
CZ20024037A3 (cs) 2004-01-14
MXPA03000101A (es) 2004-09-13
NZ522001A (en) 2004-07-30
HRP20021019A2 (en) 2004-02-29
EA200300094A1 (ru) 2003-04-24
PE20020116A1 (es) 2002-02-27
UY26803A1 (es) 2002-01-31
AP2002002694A0 (en) 2002-12-31
JP2004501902A (ja) 2004-01-22
WO2002000630A1 (en) 2002-01-03
GT200100124A (es) 2002-06-27
AU2001283861A1 (en) 2002-01-08
AR031854A1 (es) 2003-10-08
BR0112082A (pt) 2003-05-06
DE10031971A1 (de) 2002-01-10
ECSP024413A (es) 2003-03-31
HUP0300900A3 (en) 2004-01-28
OA12301A (en) 2003-11-10
YU99802A (sh) 2005-11-28
EP1299363A1 (en) 2003-04-09
PL365127A1 (en) 2004-12-27
SK17642002A3 (sk) 2004-05-04
NO20026193D0 (no) 2002-12-23
MA26924A1 (fr) 2004-12-20
ZA200209717B (en) 2003-12-01
HUP0300900A2 (hu) 2003-10-28
DZ3342A1 (fr) 2002-01-03
US20040034022A1 (en) 2004-02-19
CN1438994A (zh) 2003-08-27
HN2001000134A (es) 2001-09-11
EE200200714A (et) 2004-08-16
PA8520801A1 (es) 2003-06-30
KR20030014403A (ko) 2003-02-17
BG107352A (bg) 2003-07-31
CA2412535A1 (en) 2002-01-03
UA73588C2 (en) 2005-08-15

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