SU589914A3 - Способ получени производных 1,4-ди- окиси 1,2,4-бензтриазина - Google Patents
Способ получени производных 1,4-ди- окиси 1,2,4-бензтриазинаInfo
- Publication number
- SU589914A3 SU589914A3 SU742078807A SU2078807A SU589914A3 SU 589914 A3 SU589914 A3 SU 589914A3 SU 742078807 A SU742078807 A SU 742078807A SU 2078807 A SU2078807 A SU 2078807A SU 589914 A3 SU589914 A3 SU 589914A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- dimethyl
- benztriazine
- oxide
- hydrogen
- methyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- BHHRGAKNBXQGIO-UHFFFAOYSA-N 1,2,4-benzotriazin-3-amine Chemical compound C1=CC=CC2=NC(N)=NN=C21 BHHRGAKNBXQGIO-UHFFFAOYSA-N 0.000 claims 2
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 claims 2
- ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 claims 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N Vilsmeier-Haack reagent Natural products CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000001475 halogen functional group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims 2
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 150000001409 amidines Chemical class 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- -1 heterocyclic amines Chemical class 0.000 claims 1
- 229930195733 hydrocarbon Natural products 0.000 claims 1
- 150000002430 hydrocarbons Chemical class 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002244 precipitate Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
- C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Paints Or Removers (AREA)
- Fodder In General (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH155573A CH576231A5 (en) | 1973-02-02 | 1973-02-02 | 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth |
| CH1273373A CH576459A5 (en) | 1973-09-05 | 1973-09-05 | 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU589914A3 true SU589914A3 (ru) | 1978-01-25 |
Family
ID=25687988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU742078807A SU589914A3 (ru) | 1973-02-02 | 1974-11-28 | Способ получени производных 1,4-ди- окиси 1,2,4-бензтриазина |
Country Status (12)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2468021C2 (ru) * | 2004-08-25 | 2012-11-27 | Таргеджен, Инк. | Гетероциклические соединения и их применение |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2538179C2 (de) * | 1975-08-27 | 1986-05-28 | Bayer Ag, 5090 Leverkusen | 3-Alkoxy-benzo-1,2,4-triazine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Fungizide |
| ZA78934B (en) * | 1977-02-22 | 1979-01-31 | Ciba Geigy Ag | Novel heterocyclic compounds |
| DE2802488A1 (de) * | 1978-01-20 | 1979-07-26 | Bayer Ag | 3-azolyl-benzotriazine und -benzotriazin-1-oxide, verfahren zu ihrer herstellung, sowie ihre verwendung zur bekaempfung von pflanzenkrankheiten |
| NZ194612A (en) * | 1979-08-31 | 1982-12-21 | Ici Australia Ltd | Benzotriazine derivatives intermediates and herbicidal compositions |
| US5175287A (en) * | 1986-09-25 | 1992-12-29 | S R I International | Process for preparing 1,2,4-benzotriazine oxides |
| US5616584A (en) | 1986-09-25 | 1997-04-01 | Sri International | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
| DE3790581T1 (US08063081-20111122-C00115.png) * | 1986-09-25 | 1988-08-25 | ||
| IE62911B1 (en) * | 1988-03-18 | 1995-03-08 | Stanford Res Inst Int | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
| GR1000941B (el) * | 1989-03-17 | 1993-03-16 | Stanford Res Inst Int | Μεθοδος παρασκευης οξειδιων 1,2,4,βενζοτριαζινης. |
| JP3034541B2 (ja) * | 1989-09-18 | 2000-04-17 | エスアールアイ インターナショナル | 放射線増感剤および選択的細胞毒性物質としての１，２，４―ベンゾトリアジンオキシド |
| DE19651415A1 (de) * | 1996-12-11 | 1998-06-18 | Henkel Ecolab Gmbh & Co Ohg | Verfahren zur Instrumentendesinfektion |
| WO2003055482A1 (en) * | 2001-12-21 | 2003-07-10 | Novo Nordisk A/S | Amide derivatives as gk activators |
| CA2744893A1 (en) | 2002-06-27 | 2004-01-08 | Novo Nordisk A/S | Aryl carbonyl derivatives as glucokinase activators |
| US20050282814A1 (en) * | 2002-10-03 | 2005-12-22 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
| MXPA06007667A (es) | 2004-01-06 | 2006-09-01 | Novo Nordisk As | Heteroaril-ureas y su uso como activadores de glucocinasa. |
| NZ588139A (en) * | 2004-04-08 | 2012-02-24 | Targegen Inc | 7-Aryl-3-arylamino-benzo[1,2,4]triazine derivatives |
| AU2006254825A1 (en) * | 2005-06-08 | 2006-12-14 | Targegen, Inc. | Methods and compositions for the treatment of ocular disorders |
| ATE547396T1 (de) | 2005-07-08 | 2012-03-15 | Novo Nordisk As | Dicycloalkylcarbamoyl-harnstoffe als glucokinase- aktivatoren |
| EP1904467B1 (en) | 2005-07-14 | 2013-05-01 | Novo Nordisk A/S | Urea glucokinase activators |
| US8133900B2 (en) * | 2005-11-01 | 2012-03-13 | Targegen, Inc. | Use of bi-aryl meta-pyrimidine inhibitors of kinases |
| US8604042B2 (en) * | 2005-11-01 | 2013-12-10 | Targegen, Inc. | Bi-aryl meta-pyrimidine inhibitors of kinases |
| PT1951684T (pt) | 2005-11-01 | 2016-10-13 | Targegen Inc | Inibidores de cinases de tipo biaril-meta-pirimidina |
| US8138185B2 (en) | 2007-01-09 | 2012-03-20 | Novo Nordisk A/S | Urea glucokinase activators |
| US8318778B2 (en) | 2007-01-11 | 2012-11-27 | Novo Nordisk A/S | Urea glucokinase activators |
| WO2012060847A1 (en) | 2010-11-07 | 2012-05-10 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
| JP2015500295A (ja) * | 2011-12-07 | 2015-01-05 | エスアールアイ インターナショナルＳＲＩ Ｉｎｔｅｒｎａｔｉｏｎａｌ | ヒト結核菌を標的とする医薬としてのベンゾトリアジンオキサイド類 |
| CN112040945A (zh) | 2018-06-12 | 2020-12-04 | Vtv治疗有限责任公司 | 葡萄糖激酶激活剂与胰岛素或胰岛素类似物组合的治疗用途 |
| CN115894385A (zh) * | 2023-01-09 | 2023-04-04 | 中国科学院长春应用化学研究所 | 替拉扎明衍生物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957779A (en) * | 1972-11-15 | 1976-05-18 | Bayer Aktiengesellschaft | Benzo-1,2,4-triazines |
| US3991189A (en) * | 1972-11-15 | 1976-11-09 | Bayer Aktiengesellschaft | Microbiocidal methods and compositions using substituted 1,2,4-triazine-1,4-di-N-oxide derivatives |
| SE7501624L (US08063081-20111122-C00115.png) * | 1974-03-15 | 1975-09-16 | Ciba Geigy Ag |
-
1974
- 1974-01-22 IE IE127/74A patent/IE38778B1/xx unknown
- 1974-01-22 IL IL44058A patent/IL44058A/xx unknown
- 1974-01-23 CA CA74190796A patent/CA1049014A/en not_active Expired
- 1974-01-30 DE DE2404375A patent/DE2404375A1/de not_active Withdrawn
- 1974-01-31 NL NL7401370A patent/NL7401370A/xx not_active Application Discontinuation
- 1974-02-01 GB GB486274A patent/GB1465405A/en not_active Expired
- 1974-02-01 FR FR7403419A patent/FR2215967B1/fr not_active Expired
- 1974-02-01 JP JP49014043A patent/JPS49124235A/ja active Pending
- 1974-02-01 BE BE140468A patent/BE810511A/xx unknown
- 1974-11-28 SU SU742078807A patent/SU589914A3/ru active
-
1975
- 1975-01-01 AR AR258398A patent/AR207145A1/es active
-
1977
- 1977-10-19 US US05/843,473 patent/US4160833A/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2468021C2 (ru) * | 2004-08-25 | 2012-11-27 | Таргеджен, Инк. | Гетероциклические соединения и их применение |
Also Published As
| Publication number | Publication date |
|---|---|
| BE810511A (fr) | 1974-08-01 |
| US4160833A (en) | 1979-07-10 |
| AU6485674A (en) | 1975-07-24 |
| AR207145A1 (es) | 1976-09-15 |
| FR2215967B1 (US08063081-20111122-C00115.png) | 1977-01-28 |
| IE38778B1 (en) | 1978-05-24 |
| GB1465405A (en) | 1977-02-23 |
| NL7401370A (US08063081-20111122-C00115.png) | 1974-08-06 |
| DE2404375A1 (de) | 1974-08-08 |
| JPS49124235A (US08063081-20111122-C00115.png) | 1974-11-28 |
| FR2215967A1 (US08063081-20111122-C00115.png) | 1974-08-30 |
| CA1049014A (en) | 1979-02-20 |
| IL44058A (en) | 1978-10-31 |
| IL44058A0 (en) | 1974-05-16 |
| IE38778L (en) | 1974-08-02 |
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