SU567410A3 - Method of preparation of aryl piperazine derivatives of adenine of adenine and salts thereof - Google Patents
Method of preparation of aryl piperazine derivatives of adenine of adenine and salts thereofInfo
- Publication number
- SU567410A3 SU567410A3 SU7502092456A SU2092456A SU567410A3 SU 567410 A3 SU567410 A3 SU 567410A3 SU 7502092456 A SU7502092456 A SU 7502092456A SU 2092456 A SU2092456 A SU 2092456A SU 567410 A3 SU567410 A3 SU 567410A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- adenine
- salts
- preparation
- piperazine derivatives
- aryl piperazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Description
(54) СПОСОБ ПОЛУЧЕНИЯ АРИЛПИПЕРАЗИНОВЫХ ПРОИЗВОДНЫХ АДЕНИНА ИЛИ ИХ СОЛЕЙ(54) METHOD FOR OBTAINING ARYLPIPERAZINE DERIVATIVES OF ADENIN OR THEIR SALTS
X- СН2 - СН2- СН2 -X-CH2 - CH2-CH2 -
11eleven
где R имеет указанные выше значени , X- атом галогена,where R is as defined above, X is a halogen atom,
в инертном растворителе, в присутствии кислотосв эывающего срепства при температуреin an inert solvent, in the presence of acid retaining sheds at temperature
кипени примен емого растворител , и целевой продукт выдел ют в виде основани или соли.boiling the solvent used, and the desired product is isolated in the form of a base or salt.
Реакцию аденина с соедииенилми по формуле II 25 целесообразно осуществл ть в щелочной среде, преThe reaction of adenine with sodeenilmi according to formula II 25 is advisable to carry out in an alkaline medium, pre
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2400421A DE2400421A1 (en) | 1974-01-05 | 1974-01-05 | DERIVATIVES OF ADENINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU567410A3 true SU567410A3 (en) | 1977-07-30 |
Family
ID=5904202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU7502092456A SU567410A3 (en) | 1974-01-05 | 1975-01-03 | Method of preparation of aryl piperazine derivatives of adenine of adenine and salts thereof |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS50116490A (en) |
| AR (1) | AR203134A1 (en) |
| AT (1) | AT334389B (en) |
| BE (1) | BE824073A (en) |
| BG (1) | BG26199A3 (en) |
| CA (1) | CA1018159A (en) |
| CH (1) | CH594669A5 (en) |
| CS (1) | CS183779B2 (en) |
| DD (1) | DD117221A5 (en) |
| DE (1) | DE2400421A1 (en) |
| DK (1) | DK132433C (en) |
| ES (1) | ES433453A1 (en) |
| FI (1) | FI379574A (en) |
| FR (1) | FR2271826B1 (en) |
| GB (1) | GB1435886A (en) |
| HU (1) | HU168906B (en) |
| NL (1) | NL7416997A (en) |
| PL (1) | PL92422B1 (en) |
| RO (1) | RO66566A (en) |
| SE (1) | SE7500055L (en) |
| SU (1) | SU567410A3 (en) |
| ZA (1) | ZA756B (en) |
-
1974
- 1974-01-05 DE DE2400421A patent/DE2400421A1/en not_active Withdrawn
- 1974-12-20 BG BG7428618A patent/BG26199A3/xx unknown
- 1974-12-23 CA CA216,879A patent/CA1018159A/en not_active Expired
- 1974-12-25 JP JP50004213A patent/JPS50116490A/ja active Pending
- 1974-12-30 AR AR257163A patent/AR203134A1/en active
- 1974-12-30 DK DK690474A patent/DK132433C/en active
- 1974-12-30 FI FI3795/74A patent/FI379574A/fi unknown
- 1974-12-30 ES ES433453A patent/ES433453A1/en not_active Expired
- 1974-12-30 RO RO7481009A patent/RO66566A/en unknown
- 1974-12-30 NL NL7416997A patent/NL7416997A/en not_active Application Discontinuation
- 1974-12-31 GB GB5614674A patent/GB1435886A/en not_active Expired
- 1974-12-31 CH CH1740774A patent/CH594669A5/xx not_active IP Right Cessation
-
1975
- 1975-01-02 ZA ZA00750006A patent/ZA756B/en unknown
- 1975-01-02 CS CS7500000038A patent/CS183779B2/en unknown
- 1975-01-02 DD DD183476A patent/DD117221A5/xx unknown
- 1975-01-02 AT AT775*BA patent/AT334389B/en not_active IP Right Cessation
- 1975-01-03 SE SE7500055A patent/SE7500055L/xx unknown
- 1975-01-03 FR FR7500105A patent/FR2271826B1/fr not_active Expired
- 1975-01-03 BE BE152122A patent/BE824073A/en unknown
- 1975-01-03 HU HUBO1529A patent/HU168906B/hu unknown
- 1975-01-03 SU SU7502092456A patent/SU567410A3/en active
- 1975-01-04 PL PL1975177149A patent/PL92422B1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT334389B (en) | 1976-01-10 |
| DK690474A (en) | 1975-09-01 |
| PL92422B1 (en) | 1977-04-30 |
| ES433453A1 (en) | 1976-12-01 |
| CH594669A5 (en) | 1978-01-13 |
| FI379574A (en) | 1975-07-06 |
| CS183779B2 (en) | 1978-07-31 |
| ZA756B (en) | 1976-01-28 |
| HU168906B (en) | 1976-08-28 |
| FR2271826A1 (en) | 1975-12-19 |
| ATA775A (en) | 1976-05-15 |
| NL7416997A (en) | 1975-07-08 |
| DD117221A5 (en) | 1976-01-05 |
| CA1018159A (en) | 1977-09-27 |
| AU7702274A (en) | 1976-07-01 |
| GB1435886A (en) | 1976-05-19 |
| RO66566A (en) | 1980-03-15 |
| DK132433C (en) | 1976-05-10 |
| DE2400421A1 (en) | 1975-07-17 |
| BG26199A3 (en) | 1979-02-15 |
| JPS50116490A (en) | 1975-09-11 |
| AR203134A1 (en) | 1975-08-14 |
| BE824073A (en) | 1975-07-03 |
| FR2271826B1 (en) | 1979-06-08 |
| DK132433B (en) | 1975-12-08 |
| SE7500055L (en) | 1975-07-07 |
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