SE443981B - ANALOGY PROCEDURE FOR PREPARING SYN-ISOMERS OF 3.7 DISUBSTITUTED 3-CEFEM-4-CARBOXYLIC ACID COMPOUNDS - Google Patents
ANALOGY PROCEDURE FOR PREPARING SYN-ISOMERS OF 3.7 DISUBSTITUTED 3-CEFEM-4-CARBOXYLIC ACID COMPOUNDSInfo
- Publication number
- SE443981B SE443981B SE7701964A SE7701964A SE443981B SE 443981 B SE443981 B SE 443981B SE 7701964 A SE7701964 A SE 7701964A SE 7701964 A SE7701964 A SE 7701964A SE 443981 B SE443981 B SE 443981B
- Authority
- SE
- Sweden
- Prior art keywords
- cefem
- disubstituted
- isomers
- carboxylic acid
- acid compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB14916/76A GB1576625A (en) | 1976-04-12 | 1976-04-12 | Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof |
| GB2349076 | 1976-06-07 | ||
| JP51125826A JPS5941995B2 (en) | 1976-04-12 | 1976-10-19 | 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and salts thereof and methods for producing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7701964L SE7701964L (en) | 1977-10-13 |
| SE443981B true SE443981B (en) | 1986-03-17 |
Family
ID=27257189
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7701964A SE443981B (en) | 1976-04-12 | 1977-02-22 | ANALOGY PROCEDURE FOR PREPARING SYN-ISOMERS OF 3.7 DISUBSTITUTED 3-CEFEM-4-CARBOXYLIC ACID COMPOUNDS |
| SE8304465A SE457351B (en) | 1976-04-12 | 1983-08-17 | TIAZOLE DERIVATIVES USED AS INTERMEDIATE FOR THE PREPARATION OF 3.7 DISUBSTITUTED 3-CEFEM-4-CARBOXYLIC ACID COMPOUNDS AND PROCEDURES FOR PREPARING THEREOF |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8304465A SE457351B (en) | 1976-04-12 | 1983-08-17 | TIAZOLE DERIVATIVES USED AS INTERMEDIATE FOR THE PREPARATION OF 3.7 DISUBSTITUTED 3-CEFEM-4-CARBOXYLIC ACID COMPOUNDS AND PROCEDURES FOR PREPARING THEREOF |
Country Status (13)
| Country | Link |
|---|---|
| AR (2) | AR227864A1 (en) |
| AT (1) | AT358728B (en) |
| CA (1) | CA1337522C (en) |
| CH (2) | CH638532A5 (en) |
| DE (1) | DE2707565A1 (en) |
| DK (1) | DK162391C (en) |
| ES (7) | ES457191A1 (en) |
| FR (1) | FR2348219A1 (en) |
| HU (1) | HU177441B (en) |
| IE (1) | IE45597B1 (en) |
| MX (1) | MX4985E (en) |
| NL (1) | NL191259C (en) |
| SE (2) | SE443981B (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3192167A (en) * | 1962-09-20 | 1965-06-29 | Ogawa Abiko | Low pressure liquid vaporizer which is electrically heated |
| BE878514A (en) * | 1978-09-04 | 1980-02-29 | Fujisawa Pharmaceutical Co | PROCESS FOR THE PREPARATION OF 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS WITH DISUBSTITUTION IN POSITIONS 3 AND 7, NOVEL PRODUCTS THUS OBTAINED AND THEIR USE FOR THEIR ANTIBACTERIAL ACTIVITY |
| DE2715385A1 (en) * | 1976-04-14 | 1977-11-10 | Takeda Chemical Industries Ltd | CEPHALOSPORIN DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THEM |
| FR2381053A1 (en) * | 1977-02-18 | 1978-09-15 | Roussel Uclaf | NEW OXIMES DERIVED FROM 3-THIADIAZOLYL THIOMETHYL 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
| PH17188A (en) | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
| FR2399418A1 (en) * | 1977-03-14 | 1979-03-02 | Fujisawa Pharmaceutical Co | Heterocyclyl-imino-acetamido-cephalosporin derivs. |
| SE439312B (en) * | 1977-03-25 | 1985-06-10 | Roussel Uclaf | SET TO MAKE NEW OXIME DERIVATIVES OF 3-ACETOXIMETHYL-7-AMINOTIAZOLYLACETAMIDO CEPHALOSPORANIC ACID |
| DE2714880A1 (en) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION |
| JPS5498795A (en) * | 1978-01-13 | 1979-08-03 | Takeda Chem Ind Ltd | Cephalosporin derivative and its preparation |
| FR2432521A1 (en) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS |
| FR2553770B2 (en) * | 1978-03-31 | 1986-03-14 | Roussel Uclaf | NOVEL PRODUCTS DERIVED FROM ACID 2 (2-AMINO THIAZOL-4-YL) 2-ALCOXY-IMINO ACETIC SUBSTITUTED ON OXIME AND THEIR PREPARATION PROCESS |
| FR2421907A1 (en) * | 1978-04-07 | 1979-11-02 | Roussel Uclaf | NEW CEPHALOSPORINS DERIVED FROM 7- / 2- (2-AMINO 4-THIAZOLYL) 2- (CARBOXYMETHOXYIMINO / ACETAMIDO 3-SUBSTITUTE CEPHALOSPORANIC ACID, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
| FR2438051A2 (en) * | 1978-10-05 | 1980-04-30 | Roussel Uclaf | 3-Azido:methyl-3-cephem-4-carboxylic acid derivs. - useful as broad-spectrum antibacterial agents and disinfectants (BE 15.10.79) |
| MC1259A1 (en) | 1978-05-30 | 1980-01-14 | Hoffmann La Roche | ACYL DERIVATIVES |
| US4284631A (en) * | 1978-07-31 | 1981-08-18 | Fujisawa Pharmaceutical Co., Ltd. | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them |
| FR2453161A1 (en) * | 1978-08-31 | 1980-10-31 | Fujisawa Pharmaceutical Co | Antibacterial amino-thiazolyl cephalosporin derivs. |
| US4341775A (en) * | 1978-09-11 | 1982-07-27 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| DE2965943D1 (en) * | 1978-10-17 | 1983-08-25 | Fujisawa Pharmaceutical Co | Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds |
| DE2945248A1 (en) * | 1978-11-13 | 1980-05-22 | Fujisawa Pharmaceutical Co | CEPHEM COMPOUNDS, METHOD FOR THEIR PRODUCTION AND ANTIBACTERIAL PHARMACEUTICAL AGENTS CONTAINING THE SAME |
| FR2448543A1 (en) * | 1979-02-09 | 1980-09-05 | Roussel Uclaf | NOVEL OXIMES O-SUBSTITUTED BY A RADICAL COMPRISING A QUATERNARY AMMONIUM AND DERIVATIVES OF 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
| FR2461713A1 (en) * | 1979-07-19 | 1981-02-06 | Roussel Uclaf | SUBSTITUTED ALKYLOXIMIC NEWS DERIVED FROM 7- (2-AMINO 4-THIAZOLYL) ACETAMIDO CEPHALOSPORANIC ACID, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS |
| FR2462439A1 (en) * | 1979-07-26 | 1981-02-13 | Roussel Uclaf | NOVEL PROCESS FOR THE PREPARATION OF PRODUCTS DERIVED FROM 7 - / (2-ARYL) 2-HYDROXYIMINO ACETAMIDO / CEPHALOSPORANIC ACID |
| IL61458A0 (en) * | 1979-12-07 | 1980-12-31 | Erba Farmitalia | N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them |
| FR2506307A1 (en) * | 1981-05-22 | 1982-11-26 | Roussel Uclaf | 7-thiazolyl-acetamido-cephalosporin oxime derivs. - useful as broad spectrum antibacterials and disinfectants (BE 1.10.79) |
| US4426528A (en) * | 1982-04-01 | 1984-01-17 | Eli Lilly And Company | Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid |
| FR2532936A1 (en) * | 1982-09-13 | 1984-03-16 | Roussel Uclaf | New 2-aminothiazolyl-4-ylacetic acid derivatives containing a substituted oxime functional group and process for their preparation. |
| GB8324152D0 (en) * | 1983-09-09 | 1983-10-12 | Glaxo Group Ltd | Chemical process |
| IT8448798A0 (en) * | 1983-09-12 | 1984-09-05 | Biochemie Gmbh | PROCEDURE FOR THE PREPARATION OF CEPHALOSPORIN-TYPE ANTIBIOTICS |
| GB2161476B (en) * | 1984-05-25 | 1988-01-27 | Toyama Chemical Co Ltd | 2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins |
| DE3750411T2 (en) * | 1986-04-14 | 1995-03-16 | Banyu Pharma Co Ltd | Cephalosporin derivatives, processes for their preparation and antibacterial preparations. |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
| NZ176206A (en) * | 1973-12-25 | 1978-03-06 | Takeda Chemical Industries Ltd | Cephalosporins |
| DK154939C (en) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | METHOD OF ANALOGUE FOR THE PREPARATION OF THIAZOLYLACETAMIDO-CEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF |
| NO760358L (en) * | 1975-02-04 | 1976-08-05 | Fujisawa Pharmaceutical Co | |
| SE440655B (en) * | 1976-01-23 | 1985-08-12 | Roussel Uclaf | SET TO MAKE NEW OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID |
| DE2760123C2 (en) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporanic acids, their preparation and pharmaceutical compositions containing them |
| FR2346014A1 (en) * | 1976-01-23 | 1977-10-28 | Roussel Uclaf | Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity |
| FR2345153A1 (en) * | 1976-03-25 | 1977-10-21 | Roussel Uclaf | NEW ALCOYLOXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
| DE2715385A1 (en) * | 1976-04-14 | 1977-11-10 | Takeda Chemical Industries Ltd | CEPHALOSPORIN DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THEM |
-
1977
- 1977-02-21 DK DK075077A patent/DK162391C/en active
- 1977-02-22 DE DE19772707565 patent/DE2707565A1/en active Granted
- 1977-02-22 SE SE7701964A patent/SE443981B/en not_active IP Right Cessation
- 1977-02-23 CA CA000272430A patent/CA1337522C/en not_active Expired - Lifetime
- 1977-02-25 CH CH244777A patent/CH638532A5/en not_active IP Right Cessation
- 1977-02-28 HU HU77FU348A patent/HU177441B/en unknown
- 1977-03-01 IE IE440/77A patent/IE45597B1/en not_active IP Right Cessation
- 1977-03-02 AT AT138477A patent/AT358728B/en not_active IP Right Cessation
- 1977-03-10 FR FR7707173A patent/FR2348219A1/en active Granted
- 1977-03-25 ES ES457191A patent/ES457191A1/en not_active Expired
- 1977-04-11 MX MX775624U patent/MX4985E/en unknown
- 1977-04-12 NL NL7703969A patent/NL191259C/en not_active IP Right Cessation
- 1977-04-20 AR AR257178A patent/AR227864A1/en active
-
1978
- 1978-03-27 AR AR271541A patent/AR223143A1/en active
- 1978-04-12 ES ES468719A patent/ES468719A1/en not_active Expired
-
1979
- 1979-02-15 ES ES477741A patent/ES477741A1/en not_active Expired
- 1979-10-16 ES ES485063A patent/ES485063A1/en not_active Expired
- 1979-10-16 ES ES485064A patent/ES485064A1/en not_active Expired
- 1979-10-16 ES ES485062A patent/ES485062A1/en not_active Expired
- 1979-10-16 ES ES485061A patent/ES485061A1/en not_active Expired
-
1983
- 1983-07-26 CH CH409583A patent/CH643557A5/en not_active IP Right Cessation
- 1983-08-17 SE SE8304465A patent/SE457351B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES485064A1 (en) | 1980-10-01 |
| DE2707565A1 (en) | 1978-02-23 |
| ES485061A1 (en) | 1980-06-16 |
| SE8304465D0 (en) | 1983-08-17 |
| ES457191A1 (en) | 1978-08-16 |
| SE7701964L (en) | 1977-10-13 |
| FR2348219A1 (en) | 1977-11-10 |
| ES477741A1 (en) | 1980-04-01 |
| MX4985E (en) | 1983-01-31 |
| NL191259B (en) | 1994-11-16 |
| DE2707565C2 (en) | 1988-06-30 |
| AR227864A1 (en) | 1982-12-30 |
| DK162391B (en) | 1991-10-21 |
| AT358728B (en) | 1980-09-25 |
| ES485062A1 (en) | 1980-06-16 |
| CH643557A5 (en) | 1984-06-15 |
| ES468719A1 (en) | 1979-10-16 |
| ES485063A1 (en) | 1980-06-16 |
| ATA138477A (en) | 1980-02-15 |
| CH638532A5 (en) | 1983-09-30 |
| FR2348219B1 (en) | 1982-12-03 |
| DK75077A (en) | 1977-10-13 |
| IE45597B1 (en) | 1982-10-06 |
| HU177441B (en) | 1981-10-28 |
| NL191259C (en) | 1995-04-18 |
| SE457351B (en) | 1988-12-19 |
| IE45597L (en) | 1977-10-12 |
| DK162391C (en) | 1992-03-09 |
| NL7703969A (en) | 1977-10-14 |
| CA1337522C (en) | 1995-11-07 |
| AR223143A1 (en) | 1981-07-31 |
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