ES433453A1 - Arylpiperazine derivatives of adenine - Google Patents

Arylpiperazine derivatives of adenine

Info

Publication number
ES433453A1
ES433453A1 ES433453A ES433453A ES433453A1 ES 433453 A1 ES433453 A1 ES 433453A1 ES 433453 A ES433453 A ES 433453A ES 433453 A ES433453 A ES 433453A ES 433453 A1 ES433453 A1 ES 433453A1
Authority
ES
Spain
Prior art keywords
adenine
arylpiperazine
general formula
arylpiperazine derivatives
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES433453A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES433453A1 publication Critical patent/ES433453A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • C07D473/34Nitrogen atom attached in position 6, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Procedure for the preparation of arylpiperazine derivatives of adenine of the general formula I **(See formula)** in which R means a lower alcohol radical, characterized in that adenine, possibly in the form of a salt, is reacted with an arylpiperazine derivative of the general formula II **(See formula)** where R has the meanings indicated above and X represents a reactive radical, and the reaction product is optionally converted with an acid into a pharmacologically compatible salt. (Machine-translation by Google Translate, not legally binding)
ES433453A 1974-01-05 1974-12-30 Arylpiperazine derivatives of adenine Expired ES433453A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2400421A DE2400421A1 (en) 1974-01-05 1974-01-05 DERIVATIVES OF ADENINE

Publications (1)

Publication Number Publication Date
ES433453A1 true ES433453A1 (en) 1976-12-01

Family

ID=5904202

Family Applications (1)

Application Number Title Priority Date Filing Date
ES433453A Expired ES433453A1 (en) 1974-01-05 1974-12-30 Arylpiperazine derivatives of adenine

Country Status (22)

Country Link
JP (1) JPS50116490A (en)
AR (1) AR203134A1 (en)
AT (1) AT334389B (en)
BE (1) BE824073A (en)
BG (1) BG26199A3 (en)
CA (1) CA1018159A (en)
CH (1) CH594669A5 (en)
CS (1) CS183779B2 (en)
DD (1) DD117221A5 (en)
DE (1) DE2400421A1 (en)
DK (1) DK132433C (en)
ES (1) ES433453A1 (en)
FI (1) FI379574A (en)
FR (1) FR2271826B1 (en)
GB (1) GB1435886A (en)
HU (1) HU168906B (en)
NL (1) NL7416997A (en)
PL (1) PL92422B1 (en)
RO (1) RO66566A (en)
SE (1) SE7500055L (en)
SU (1) SU567410A3 (en)
ZA (1) ZA756B (en)

Also Published As

Publication number Publication date
FR2271826A1 (en) 1975-12-19
FR2271826B1 (en) 1979-06-08
AU7702274A (en) 1976-07-01
FI379574A (en) 1975-07-06
DK132433C (en) 1976-05-10
DK132433B (en) 1975-12-08
BE824073A (en) 1975-07-03
NL7416997A (en) 1975-07-08
SU567410A3 (en) 1977-07-30
HU168906B (en) 1976-08-28
GB1435886A (en) 1976-05-19
JPS50116490A (en) 1975-09-11
DE2400421A1 (en) 1975-07-17
CH594669A5 (en) 1978-01-13
ATA775A (en) 1976-05-15
CA1018159A (en) 1977-09-27
AR203134A1 (en) 1975-08-14
DK690474A (en) 1975-09-01
SE7500055L (en) 1975-07-07
DD117221A5 (en) 1976-01-05
CS183779B2 (en) 1978-07-31
RO66566A (en) 1980-03-15
AT334389B (en) 1976-01-10
BG26199A3 (en) 1979-02-15
ZA756B (en) 1976-01-28
PL92422B1 (en) 1977-04-30

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