ES419319A1 - Amide derivatives of 3-benzoylphenyl-alkanoic acids - Google Patents

Amide derivatives of 3-benzoylphenyl-alkanoic acids

Info

Publication number
ES419319A1
ES419319A1 ES419319A ES419319A ES419319A1 ES 419319 A1 ES419319 A1 ES 419319A1 ES 419319 A ES419319 A ES 419319A ES 419319 A ES419319 A ES 419319A ES 419319 A1 ES419319 A1 ES 419319A1
Authority
ES
Spain
Prior art keywords
acids
degrees
benzoylphenyl
formula
benzoil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES419319A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antonio Gallardo SA
Original Assignee
Antonio Gallardo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antonio Gallardo SA filed Critical Antonio Gallardo SA
Priority to ES419319A priority Critical patent/ES419319A1/en
Priority to GB4309874A priority patent/GB1436502A/en
Publication of ES419319A1 publication Critical patent/ES419319A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58Preparation of carboxylic acid halides
    • C07C51/60Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • DTEXTILES; PAPER
    • D03WEAVING
    • D03CSHEDDING MECHANISMS; PATTERN CARDS OR CHAINS; PUNCHING OF CARDS; DESIGNING PATTERNS
    • D03C13/00Shedding mechanisms not otherwise provided for
    • DTEXTILES; PAPER
    • D03WEAVING
    • D03DWOVEN FABRICS; METHODS OF WEAVING; LOOMS
    • D03D47/00Looms in which bulk supply of weft does not pass through shed, e.g. shuttleless looms, gripper shuttle looms, dummy shuttle looms
    • D03D47/12Looms in which bulk supply of weft does not pass through shed, e.g. shuttleless looms, gripper shuttle looms, dummy shuttle looms wherein single picks of weft thread are inserted, i.e. with shedding between each pick
    • D03D47/26Travelling-wave-shed looms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDURE FOR THE OBTAINING OF DERIVATIVES OF 3-BENZOYLPHENYL ALCANOIC ACIDS OF GENERAL FORMULA ** FORMULA ** WHERE R IS H, ALKYL OR CYCLLOALKYL R1 IS H OR LOWER ALKYL AND R2 HETEROCIDAL VAHICALES. THE ACID CHLORIDE ** FORMULA ** IS REACTED WITH AMINES OF THE NHR1R2 TYPE USING AS A SOLVENT ACETONE OR OTHER, AND AS A NAOH, KOH OR OTHER BASE. THE TEMPERATURE IS MAINTAINED BETWEEN 70 AND 90 DEGREES C. THE ACID CHLORIDE THAT IS USED IS OBTAINED BY REACTION OF THE 3-BENZOIL-PHENYLALCANOIC ACIDS WITH THIONYL CHLORIDE AT A TEMPERATURE OF 80 DEGREES TO 120 DEGREES C. 3-BENZIL ACIDS FENILALCANOICOS ARE PREPARED BY HYDROLYSIS OF THE 3-BENZOIL-PHENYLACETONITRILS ALPHA SUBSTITUTED. THE 3-BENZOILFENILALCANOIC COMPOUNDS HAVE ACTIVITY AS ANTI-INFLAMMATORIES. (Machine-translation by Google Translate, not legally binding)
ES419319A 1973-10-04 1973-10-04 Amide derivatives of 3-benzoylphenyl-alkanoic acids Expired ES419319A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES419319A ES419319A1 (en) 1973-10-04 1973-10-04 Amide derivatives of 3-benzoylphenyl-alkanoic acids
GB4309874A GB1436502A (en) 1973-10-04 1974-10-04 Amide derivatives of 3-benzoylphenyl-alkanoic acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES419319A ES419319A1 (en) 1973-10-04 1973-10-04 Amide derivatives of 3-benzoylphenyl-alkanoic acids

Publications (1)

Publication Number Publication Date
ES419319A1 true ES419319A1 (en) 1976-03-01

Family

ID=8465138

Family Applications (1)

Application Number Title Priority Date Filing Date
ES419319A Expired ES419319A1 (en) 1973-10-04 1973-10-04 Amide derivatives of 3-benzoylphenyl-alkanoic acids

Country Status (2)

Country Link
ES (1) ES419319A1 (en)
GB (1) GB1436502A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2049647A1 (en) * 1992-07-28 1994-04-16 Menarini Lab New antiinflammatory, analgesic and anti-pyretic agents with low toxicity - are amide or ester of benzoyl-phenyl-propionic acid with amino- or hydroxy-benzoic acid (ester)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI262185B (en) 1999-10-01 2006-09-21 Eisai Co Ltd Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
PL373701A1 (en) 2002-04-26 2005-09-05 F.Hoffmann-La Roche Ag Substituted phenylacetamides and their use as glucokinase activators
MY141521A (en) 2002-12-12 2010-05-14 Hoffmann La Roche 5-substituted-six-membered heteroaromatic glucokinase activators
RU2461550C2 (en) * 2009-10-15 2012-09-20 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ПГФА Росздрава) Thiazoline ammonium 2-hydroxy-4-oxo-4-(4-chlorophenyl)-2-butenoate, having anticoagulation activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2049647A1 (en) * 1992-07-28 1994-04-16 Menarini Lab New antiinflammatory, analgesic and anti-pyretic agents with low toxicity - are amide or ester of benzoyl-phenyl-propionic acid with amino- or hydroxy-benzoic acid (ester)

Also Published As

Publication number Publication date
GB1436502A (en) 1976-05-19

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