ES2049647A1 - New antiinflammatory, analgesic and anti-pyretic agents with low toxicity - are amide or ester of benzoyl-phenyl-propionic acid with amino- or hydroxy-benzoic acid (ester) - Google Patents

New antiinflammatory, analgesic and anti-pyretic agents with low toxicity - are amide or ester of benzoyl-phenyl-propionic acid with amino- or hydroxy-benzoic acid (ester)

Info

Publication number
ES2049647A1
ES2049647A1 ES9201583A ES9201583A ES2049647A1 ES 2049647 A1 ES2049647 A1 ES 2049647A1 ES 9201583 A ES9201583 A ES 9201583A ES 9201583 A ES9201583 A ES 9201583A ES 2049647 A1 ES2049647 A1 ES 2049647A1
Authority
ES
Spain
Prior art keywords
ester
propionic acid
analgesic
low toxicity
benzoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES9201583A
Other languages
Spanish (es)
Other versions
ES2049647B1 (en
Inventor
Carganico
Torro Fos
Casellas Mauleon
Bosch Gonzalez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Menarini SA
Original Assignee
Laboratorios Menarini SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Menarini SA filed Critical Laboratorios Menarini SA
Priority to ES9201583A priority Critical patent/ES2049647B1/en
Publication of ES2049647A1 publication Critical patent/ES2049647A1/en
Application granted granted Critical
Publication of ES2049647B1 publication Critical patent/ES2049647B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for preparing new derivatives of 2-(3-benzoylphenyl) propionic acid.This invention refers to a procedure for preparing new derivatives (I) of 2-(3-benzoylphenyl) propionic acid with anti-inflammatory, analgesic and antipyretic action.In formula (I), X represents a -O- or -NH- group, and R is hydrogen, an alkyl group of 1 to 8 linear or branched carbon atoms, or an arylalkyl group of fewer than 10 carbon atoms. The compounds (I) have high anti-inflammatory power, along with very low toxicity and stomach damaging potential.< IMAGE >New derivs. of 2-(3-benzoyl phenyl) propionic acid are of formula (I), in which X is O or NH and R is H, opt. branched 1-8C alkyl, or aralkyl with less than 10C atoms.
ES9201583A 1992-07-28 1992-07-28 "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ACID 2- (3-BENZOILFENIL) PROPIONICO" Expired - Fee Related ES2049647B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9201583A ES2049647B1 (en) 1992-07-28 1992-07-28 "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ACID 2- (3-BENZOILFENIL) PROPIONICO"

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9201583A ES2049647B1 (en) 1992-07-28 1992-07-28 "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ACID 2- (3-BENZOILFENIL) PROPIONICO"

Publications (2)

Publication Number Publication Date
ES2049647A1 true ES2049647A1 (en) 1994-04-16
ES2049647B1 ES2049647B1 (en) 1994-12-16

Family

ID=8277812

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9201583A Expired - Fee Related ES2049647B1 (en) 1992-07-28 1992-07-28 "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ACID 2- (3-BENZOILFENIL) PROPIONICO"

Country Status (1)

Country Link
ES (1) ES2049647B1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3235583A (en) * 1964-07-22 1966-02-15 Norwich Pharma Co Preparation of aspirin
US3641127A (en) * 1967-01-27 1972-02-08 Rhone Poulenc Sa (3-benzoylphenyl) alkanoic acids
ES419319A1 (en) * 1973-10-04 1976-03-01 Gallardo Antonio Sa Amide derivatives of 3-benzoylphenyl-alkanoic acids

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3235583A (en) * 1964-07-22 1966-02-15 Norwich Pharma Co Preparation of aspirin
US3641127A (en) * 1967-01-27 1972-02-08 Rhone Poulenc Sa (3-benzoylphenyl) alkanoic acids
ES419319A1 (en) * 1973-10-04 1976-03-01 Gallardo Antonio Sa Amide derivatives of 3-benzoylphenyl-alkanoic acids

Also Published As

Publication number Publication date
ES2049647B1 (en) 1994-12-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040503