ES2049647A1 - New antiinflammatory, analgesic and anti-pyretic agents with low toxicity - are amide or ester of benzoyl-phenyl-propionic acid with amino- or hydroxy-benzoic acid (ester) - Google Patents
New antiinflammatory, analgesic and anti-pyretic agents with low toxicity - are amide or ester of benzoyl-phenyl-propionic acid with amino- or hydroxy-benzoic acid (ester)Info
- Publication number
- ES2049647A1 ES2049647A1 ES9201583A ES9201583A ES2049647A1 ES 2049647 A1 ES2049647 A1 ES 2049647A1 ES 9201583 A ES9201583 A ES 9201583A ES 9201583 A ES9201583 A ES 9201583A ES 2049647 A1 ES2049647 A1 ES 2049647A1
- Authority
- ES
- Spain
- Prior art keywords
- ester
- propionic acid
- analgesic
- low toxicity
- benzoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedure for preparing new derivatives of 2-(3-benzoylphenyl) propionic acid.This invention refers to a procedure for preparing new derivatives (I) of 2-(3-benzoylphenyl) propionic acid with anti-inflammatory, analgesic and antipyretic action.In formula (I), X represents a -O- or -NH- group, and R is hydrogen, an alkyl group of 1 to 8 linear or branched carbon atoms, or an arylalkyl group of fewer than 10 carbon atoms. The compounds (I) have high anti-inflammatory power, along with very low toxicity and stomach damaging potential.< IMAGE >New derivs. of 2-(3-benzoyl phenyl) propionic acid are of formula (I), in which X is O or NH and R is H, opt. branched 1-8C alkyl, or aralkyl with less than 10C atoms.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9201583A ES2049647B1 (en) | 1992-07-28 | 1992-07-28 | "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ACID 2- (3-BENZOILFENIL) PROPIONICO" |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9201583A ES2049647B1 (en) | 1992-07-28 | 1992-07-28 | "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ACID 2- (3-BENZOILFENIL) PROPIONICO" |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2049647A1 true ES2049647A1 (en) | 1994-04-16 |
ES2049647B1 ES2049647B1 (en) | 1994-12-16 |
Family
ID=8277812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9201583A Expired - Fee Related ES2049647B1 (en) | 1992-07-28 | 1992-07-28 | "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ACID 2- (3-BENZOILFENIL) PROPIONICO" |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2049647B1 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3235583A (en) * | 1964-07-22 | 1966-02-15 | Norwich Pharma Co | Preparation of aspirin |
US3641127A (en) * | 1967-01-27 | 1972-02-08 | Rhone Poulenc Sa | (3-benzoylphenyl) alkanoic acids |
ES419319A1 (en) * | 1973-10-04 | 1976-03-01 | Gallardo Antonio Sa | Amide derivatives of 3-benzoylphenyl-alkanoic acids |
-
1992
- 1992-07-28 ES ES9201583A patent/ES2049647B1/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3235583A (en) * | 1964-07-22 | 1966-02-15 | Norwich Pharma Co | Preparation of aspirin |
US3641127A (en) * | 1967-01-27 | 1972-02-08 | Rhone Poulenc Sa | (3-benzoylphenyl) alkanoic acids |
ES419319A1 (en) * | 1973-10-04 | 1976-03-01 | Gallardo Antonio Sa | Amide derivatives of 3-benzoylphenyl-alkanoic acids |
Also Published As
Publication number | Publication date |
---|---|
ES2049647B1 (en) | 1994-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20040503 |