SU492094A3 - Способ получени живой брюшнотифозной вакцины - Google Patents
Способ получени живой брюшнотифозной вакциныInfo
- Publication number
- SU492094A3 SU492094A3 SU1694985A SU1694985A SU492094A3 SU 492094 A3 SU492094 A3 SU 492094A3 SU 1694985 A SU1694985 A SU 1694985A SU 1694985 A SU1694985 A SU 1694985A SU 492094 A3 SU492094 A3 SU 492094A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- vaccine
- bacteria
- mutant
- strain
- block
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title claims description 10
- 238000000034 method Methods 0.000 title claims description 4
- 208000037386 Typhoid Diseases 0.000 title claims 2
- 201000008297 typhoid fever Diseases 0.000 title claims 2
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 3
- 230000036039 immunity Effects 0.000 claims description 2
- 241001467018 Typhis Species 0.000 claims 2
- 108091000080 Phosphotransferase Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 102000020233 phosphotransferase Human genes 0.000 claims 1
- 241000894006 Bacteria Species 0.000 description 15
- 239000002609 medium Substances 0.000 description 7
- 210000004556 brain Anatomy 0.000 description 6
- 229930182830 galactose Natural products 0.000 description 5
- 229920001817 Agar Polymers 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 239000008272 agar Substances 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 4
- 235000015097 nutrients Nutrition 0.000 description 4
- 241000699670 Mus sp. Species 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 241001515965 unidentified phage Species 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000186031 Corynebacteriaceae Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- HXXFSFRBOHSIMQ-FPRJBGLDSA-N alpha-D-galactose 1-phosphate Chemical compound OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O HXXFSFRBOHSIMQ-FPRJBGLDSA-N 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 244000052637 human pathogen Species 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 231100000219 mutagenic Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000008476 powdered milk Nutrition 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH631971A CH542928A (de) | 1971-04-29 | 1971-04-29 | Verfahren zur Herstellung einer neuen Typhus-Vakzine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU492094A3 true SU492094A3 (ru) | 1975-11-15 |
Family
ID=4307668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1694985A SU492094A3 (ru) | 1971-04-29 | 1971-08-16 | Способ получени живой брюшнотифозной вакцины |
Country Status (16)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2631924C2 (ru) * | 2011-12-22 | 2017-09-28 | Ваксимм Аг | Высокопродуктивный способ получения ослабленных штаммов salmonella |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009025000A1 (en) * | 2007-08-23 | 2009-02-26 | Indian Institute Of Science | Mutated salmonella typhi strain and use thereof in a vaccine |
-
1971
- 1971-04-29 CH CH631971A patent/CH542928A/de not_active IP Right Cessation
- 1971-06-02 ES ES392830A patent/ES392830A1/es not_active Expired
- 1971-06-09 DE DE19712128626 patent/DE2128626B2/de active Granted
- 1971-06-11 GB GB27578/71A patent/GB1291214A/en not_active Expired
- 1971-06-18 AT AT528871A patent/AT304763B/de not_active IP Right Cessation
- 1971-07-14 NL NL717109739A patent/NL146385B/xx not_active IP Right Cessation
- 1971-07-20 ZA ZA714798A patent/ZA714798B/xx unknown
- 1971-07-23 BE BE770453A patent/BE770453A/xx unknown
- 1971-07-29 DK DK373771AA patent/DK129244B/da not_active IP Right Cessation
- 1971-07-29 SE SE7109725A patent/SE397632B/xx unknown
- 1971-07-30 CA CA119,495A patent/CA939608A/en not_active Expired
- 1971-07-30 FR FR7128099A patent/FR2134325B1/fr not_active Expired
- 1971-07-30 JP JP5685971A patent/JPS5522448B1/ja active Pending
- 1971-08-16 SU SU1694985A patent/SU492094A3/ru active
- 1971-08-27 AU AU32830/71A patent/AU445536B2/en not_active Expired
-
1978
- 1978-12-06 IT IT30643/78A patent/IT1101491B/it active Protection Beyond IP Right Term
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2631924C2 (ru) * | 2011-12-22 | 2017-09-28 | Ваксимм Аг | Высокопродуктивный способ получения ослабленных штаммов salmonella |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2128626B2 (de) | 1977-07-28 |
| DE2128626C3 (enrdf_load_stackoverflow) | 1978-03-16 |
| JPS5522448B1 (enrdf_load_stackoverflow) | 1980-06-17 |
| AT304763B (de) | 1973-01-25 |
| CH542928A (de) | 1973-10-15 |
| SE397632B (sv) | 1977-11-14 |
| IT7830643A0 (it) | 1978-12-06 |
| IT1101491B (it) | 1985-09-28 |
| DK129244B (da) | 1974-09-16 |
| DK129244C (enrdf_load_stackoverflow) | 1975-02-03 |
| FR2134325A1 (enrdf_load_stackoverflow) | 1972-12-08 |
| NL7109739A (enrdf_load_stackoverflow) | 1972-10-31 |
| DE2128626A1 (de) | 1972-11-02 |
| BE770453A (fr) | 1972-01-24 |
| ZA714798B (en) | 1972-04-26 |
| CA939608A (en) | 1974-01-08 |
| GB1291214A (en) | 1972-10-04 |
| AU445536B2 (en) | 1974-02-21 |
| NL146385B (nl) | 1975-07-15 |
| FR2134325B1 (enrdf_load_stackoverflow) | 1975-02-07 |
| AU3283071A (en) | 1973-03-01 |
| ES392830A1 (es) | 1974-12-16 |
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