SU473359A3 - Способ получени бензолсульфонилмочевины - Google Patents
Способ получени бензолсульфонилмочевиныInfo
- Publication number
- SU473359A3 SU473359A3 SU1631861A SU1631861A SU473359A3 SU 473359 A3 SU473359 A3 SU 473359A3 SU 1631861 A SU1631861 A SU 1631861A SU 1631861 A SU1631861 A SU 1631861A SU 473359 A3 SU473359 A3 SU 473359A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- benzenesulfonylurea
- preparing
- acid
- urea
- methoxy
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 5
- GHDLZGOOOLEJKI-UHFFFAOYSA-N benzenesulfonylurea Chemical compound NC(=O)NS(=O)(=O)C1=CC=CC=C1 GHDLZGOOOLEJKI-UHFFFAOYSA-N 0.000 title 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 7
- 239000004202 carbamide Substances 0.000 description 5
- 239000002253 acid Substances 0.000 description 4
- -1 benzyl sulfate phenyl benzene Chemical compound 0.000 description 4
- 235000013877 carbamide Nutrition 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- UKWHYYKOEPRTIC-UHFFFAOYSA-N mercury(ii) oxide Chemical compound [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- VLXSIHLNPYRFFN-UHFFFAOYSA-N 1,4-dioxane;methanol Chemical compound OC.C1COCCO1 VLXSIHLNPYRFFN-UHFFFAOYSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- 101150067539 AMBP gene Proteins 0.000 description 1
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- 240000004160 Capsicum annuum Species 0.000 description 1
- 229910052684 Cerium Inorganic materials 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 229920000180 alkyd Polymers 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 235000011114 ammonium hydroxide Nutrition 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- ZMIGMASIKSOYAM-UHFFFAOYSA-N cerium Chemical compound [Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce] ZMIGMASIKSOYAM-UHFFFAOYSA-N 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Chemical group 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 150000002431 hydrogen Chemical group 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 229940101209 mercuric oxide Drugs 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- ZFLIKDUSUDBGCD-UHFFFAOYSA-N parabanic acid Chemical compound O=C1NC(=O)C(=O)N1 ZFLIKDUSUDBGCD-UHFFFAOYSA-N 0.000 description 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical compound OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0050793 | 1966-11-29 | ||
| DEF52939A DE1291742B (de) | 1966-11-29 | 1967-07-13 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU473359A3 true SU473359A3 (ru) | 1975-06-05 |
Family
ID=25977518
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1631861A SU473359A3 (ru) | 1966-11-29 | 1967-11-29 | Способ получени бензолсульфонилмочевины |
| SU1418959A SU460621A3 (ru) | 1966-11-29 | 1967-11-29 | Способ получени бензолсульфонилмочевины |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1418959A SU460621A3 (ru) | 1966-11-29 | 1967-11-29 | Способ получени бензолсульфонилмочевины |
Country Status (23)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957866A (en) * | 1970-09-23 | 1976-05-18 | J. Uriach & Cia S.A. | Cyclopentyl carbamide derivative and process for its production |
| US4072758A (en) * | 1970-09-23 | 1978-02-07 | J. Uriach Y Cia, S.A. | Compositions and methods for effecting glucoreduction |
| JPS54175898U (enrdf_load_stackoverflow) * | 1978-05-31 | 1979-12-12 | ||
| JPS5559632U (enrdf_load_stackoverflow) * | 1978-10-20 | 1980-04-23 | ||
| WO2018215818A1 (en) * | 2017-05-24 | 2018-11-29 | The University Of Queensland | Novel compounds and uses |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1192192B (enrdf_load_stackoverflow) * |
-
1966
- 1966-11-29 DE DE1568626A patent/DE1568626C3/de not_active Expired
-
1967
- 1967-07-13 DE DEF52939A patent/DE1291742B/de active Pending
- 1967-11-01 IL IL28873A patent/IL28873A/en unknown
- 1967-11-17 GR GR670137776A patent/GR37776B/el unknown
- 1967-11-23 DK DK587667AA patent/DK120539B/da unknown
- 1967-11-24 NL NL6716016A patent/NL6716016A/xx unknown
- 1967-11-24 FI FI673171A patent/FI45963C/fi active
- 1967-11-25 ES ES347613A patent/ES347613A1/es not_active Expired
- 1967-11-27 AT AT01272/69A patent/AT278850B/de not_active IP Right Cessation
- 1967-11-27 AT AT127169A patent/AT278849B/de not_active IP Right Cessation
- 1967-11-27 CH CH1069170A patent/CH518915A/de not_active IP Right Cessation
- 1967-11-27 CH CH1069070A patent/CH519483A/de not_active IP Right Cessation
- 1967-11-27 LU LU54967D patent/LU54967A1/xx unknown
- 1967-11-27 CH CH1068770A patent/CH519481A/de not_active IP Right Cessation
- 1967-11-27 CH CH1069270A patent/CH522608A/de not_active IP Right Cessation
- 1967-11-27 AT AT1069367A patent/AT278845B/de not_active IP Right Cessation
- 1967-11-27 CH CH1661567A patent/CH495339A/de not_active IP Right Cessation
- 1967-11-27 AT AT126869A patent/AT299971B/de not_active IP Right Cessation
- 1967-11-27 CH CH1068970A patent/CH518914A/de not_active IP Right Cessation
- 1967-11-27 AT AT127069A patent/AT289822B/de not_active IP Right Cessation
- 1967-11-27 CH CH1068670A patent/CH518913A/de not_active IP Right Cessation
- 1967-11-27 CH CH84272A patent/CH519484A/de not_active IP Right Cessation
- 1967-11-27 CH CH1068870A patent/CH519482A/de not_active IP Right Cessation
- 1967-11-28 FR FR1571292D patent/FR1571292A/fr not_active Expired
- 1967-11-28 NO NO170728A patent/NO122922B/no unknown
- 1967-11-28 OA OA53110A patent/OA03381A/xx unknown
- 1967-11-28 IT IT23246/67A patent/IT1056720B/it active
- 1967-11-28 MC MC733A patent/MC696A1/xx unknown
- 1967-11-29 CS CS2568*[A patent/CS159741B2/cs unknown
- 1967-11-29 SU SU1631861A patent/SU473359A3/ru active
- 1967-11-29 SE SE16358/67A patent/SE339221B/xx unknown
- 1967-11-29 CS CS6599A patent/CS159737B2/cs unknown
- 1967-11-29 GB GB54301/67A patent/GB1203425A/en not_active Expired
- 1967-11-29 CS CS6600A patent/CS159738B2/cs unknown
- 1967-11-29 CS CS1541*[A patent/CS159740B2/cs unknown
- 1967-11-29 CS CS6601A patent/CS159739B2/cs unknown
- 1967-11-29 BE BE707241D patent/BE707241A/xx unknown
- 1967-11-29 CS CS8447A patent/CS159734B2/cs unknown
- 1967-11-29 SU SU1418959A patent/SU460621A3/ru active
- 1967-11-29 JP JP42076359A patent/JPS5015790B1/ja active Pending
- 1967-11-29 CS CS6597A patent/CS159735B2/cs unknown
-
1968
- 1968-02-26 FR FR141253A patent/FR8367M/fr not_active Expired
-
1971
- 1971-10-25 CY CY61771A patent/CY617A/xx unknown
-
1972
- 1972-12-30 MY MY11/72A patent/MY7200011A/xx unknown
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