SU252954A1 - - Google Patents
Info
- Publication number
- SU252954A1 SU252954A1 SU1201936A SU1201936A SU252954A1 SU 252954 A1 SU252954 A1 SU 252954A1 SU 1201936 A SU1201936 A SU 1201936A SU 1201936 A SU1201936 A SU 1201936A SU 252954 A1 SU252954 A1 SU 252954A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- substituted
- alkyl
- carbamide
- benzimidazole
- derivatives
- Prior art date
Links
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 150000001408 amides Chemical class 0.000 description 2
- 125000003710 aryl alkyl group Chemical group 0.000 description 2
- 150000001556 benzimidazoles Chemical class 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 235000013877 carbamide Nutrition 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 125000000547 substituted alkyl group Chemical group 0.000 description 2
- 150000003672 ureas Chemical class 0.000 description 2
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical class NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 description 1
- PSCITZRLRGWIHI-UHFFFAOYSA-N 2-(4-aminophenyl)pyridin-3-ol Chemical compound C1=CC(N)=CC=C1C1=NC=CC=C1O PSCITZRLRGWIHI-UHFFFAOYSA-N 0.000 description 1
- ZFDILXLUXPRASO-UHFFFAOYSA-N 3,4,5-trichlorobenzene-1,2-diamine Chemical compound NC1=CC(Cl)=C(Cl)C(Cl)=C1N ZFDILXLUXPRASO-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000010933 acylation Effects 0.000 description 1
- 238000005917 acylation reaction Methods 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 150000001356 alkyl thiols Chemical class 0.000 description 1
- 125000000304 alkynyl group Chemical group 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- -1 hydride difluoroacetic acid Chemical compound 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 150000002926 oxygen Chemical class 0.000 description 1
- 235000003270 potassium fluoride Nutrition 0.000 description 1
- 239000011698 potassium fluoride Substances 0.000 description 1
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 description 1
- 125000002577 pseudohalo group Chemical group 0.000 description 1
- IBBLRJGOOANPTQ-JKVLGAQCSA-N quinapril hydrochloride Chemical class Cl.C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CC2=CC=CC=C2C1)C(O)=O)CC1=CC=CC=C1 IBBLRJGOOANPTQ-JKVLGAQCSA-N 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 125000005017 substituted alkenyl group Chemical group 0.000 description 1
- 125000004426 substituted alkynyl group Chemical group 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU252954A1 true SU252954A1 (https=) |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69306591T2 (de) | Verfahren für die herstellung von toxane derivaten | |
| Schmittel et al. | A Highly Efficient Triplet Analogue of a Thermal Biradical Cyclization—The Photochemical C2–C6 Cyclization of Enyne‐Heteroallenes | |
| SU1333234A3 (ru) | Способ получени производных N-фенилбензамида или их солей | |
| Zhang et al. | Design, synthesis and activity evaluation of indole-based double–Branched HDAC1 inhibitors | |
| SU252954A1 (https=) | ||
| Khantikaew et al. | Synthesis of (−)-benzolactam-V8 by application of asymmetric aziridination | |
| US3320272A (en) | Process for preparing z-alkoxycyclo- heptimidazole derivatives | |
| SU268299A1 (https=) | ||
| JPH0931092A (ja) | ２’−３’−ジ−ｏ−アシルａｔｐの製造法 | |
| Yassine et al. | Synthesis of New Dialkyl 2, 2′-[Carbonylbis (azanediyl)] dibenzoates via Curtius Rearrangement | |
| RU2807909C1 (ru) | 1-(фенил{ фенилимино} метил)пиперидин-2,6-дион и способ его получения | |
| Gorodnicheva et al. | Synthesis and Structure of 4-Het (aryl)-3, 5, 5-trimethoxycarbonyl-2-pyrrolidones | |
| CN116655601B (zh) | 一种奥希替尼的合成方法 | |
| SU389660A1 (https=) | ||
| SU339047A1 (https=) | ||
| SU255277A1 (ru) | СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ БЕНЗОКАРБАЗОЛАИзобретение относитс к области получени новых соединений, которые могут найти применение в синтезе биологически активных веществ.Предлагаемый способ получени производных бензокарбазола формулыROгде R —П, Alk, Аг,R — Alk, заключаетс в том, что 2-бензил- 5-метоксииндолил-З-карбоновую кислоту или ее эфир формулыR'OX^^ ^COOR"\A^J-CH2-C6H5где R —Н, Alk, Аг; R" —Н, Alk; R' —Alk; подвергают внутримолекул рной циклизации в присутствии циклизующих агентов, например полифосфорной кислоты, с последующим выделением полученного продукта известным способом.Пример 1. 1,4-Дигидро-4-кето-6-метокси | |
| RU2776069C1 (ru) | Применение 2-[бис(5-метилфуран-2-ил)метил]фенола в качестве антибактериального средства в отношении грамположительных микроорганизмов | |
| SU1192622A3 (ru) | Способ получени производных 2-хиноксалинил-1,4-диоксида | |
| RU2763728C1 (ru) | Применение 3-(2-(4-нитрофенил)-2-оксоэтилиден)морфолин-2-она в качестве средства, обладающего противомикробной активностью | |
| SU412195A1 (https=) | ||
| US3923827A (en) | Preparation of 4-imidazolin-2-ones | |
| SU379084A1 (https=) | ||
| Salikhov et al. | SYNTHESIS OF BENZOXAZINES | |
| SU603642A1 (ru) | Способ получени монотиоксамидов | |
| US3647785A (en) | Novel 3-indolylaliphatic acid anhydrides |