SU1530101A3 - Способ получени амида - Google Patents
Способ получени амида Download PDFInfo
- Publication number
- SU1530101A3 SU1530101A3 SU843764662A SU3764662A SU1530101A3 SU 1530101 A3 SU1530101 A3 SU 1530101A3 SU 843764662 A SU843764662 A SU 843764662A SU 3764662 A SU3764662 A SU 3764662A SU 1530101 A3 SU1530101 A3 SU 1530101A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- reaction
- light
- exposure
- cbs
- genus
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 24
- 150000001408 amides Chemical class 0.000 title claims description 7
- 238000006243 chemical reaction Methods 0.000 claims abstract description 63
- -1 nitrile compound Chemical class 0.000 claims abstract description 19
- 230000000694 effects Effects 0.000 claims abstract description 12
- 238000006703 hydration reaction Methods 0.000 claims abstract description 8
- 244000005700 microbiome Species 0.000 claims abstract description 7
- 108010033272 Nitrilase Proteins 0.000 claims abstract description 5
- 239000000463 material Substances 0.000 claims abstract description 3
- 210000004027 cell Anatomy 0.000 claims description 29
- 239000008363 phosphate buffer Substances 0.000 claims description 17
- 230000001580 bacterial effect Effects 0.000 claims description 16
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 claims description 15
- 241000894006 Bacteria Species 0.000 claims description 14
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 9
- JFDZBHWFFUWGJE-UHFFFAOYSA-N benzonitrile Chemical compound N#CC1=CC=CC=C1 JFDZBHWFFUWGJE-UHFFFAOYSA-N 0.000 claims description 9
- 150000002825 nitriles Chemical class 0.000 claims description 8
- 239000000725 suspension Substances 0.000 claims description 7
- FFNVQNRYTPFDDP-UHFFFAOYSA-N 2-cyanopyridine Chemical compound N#CC1=CC=CC=N1 FFNVQNRYTPFDDP-UHFFFAOYSA-N 0.000 claims description 4
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 4
- 241000186146 Brevibacterium Species 0.000 claims description 4
- 241000192041 Micrococcus Species 0.000 claims description 4
- RFFFKMOABOFIDF-UHFFFAOYSA-N Pentanenitrile Chemical compound CCCCC#N RFFFKMOABOFIDF-UHFFFAOYSA-N 0.000 claims description 4
- CUONGYYJJVDODC-UHFFFAOYSA-N malononitrile Chemical compound N#CCC#N CUONGYYJJVDODC-UHFFFAOYSA-N 0.000 claims description 4
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical compound CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 claims description 4
- KYPOHTVBFVELTG-OWOJBTEDSA-N (e)-but-2-enedinitrile Chemical compound N#C\C=C\C#N KYPOHTVBFVELTG-OWOJBTEDSA-N 0.000 claims description 3
- GYCMBHHDWRMZGG-UHFFFAOYSA-N Methylacrylonitrile Chemical compound CC(=C)C#N GYCMBHHDWRMZGG-UHFFFAOYSA-N 0.000 claims description 3
- 241000187654 Nocardia Species 0.000 claims description 3
- KVNRLNFWIYMESJ-UHFFFAOYSA-N butyronitrile Chemical compound CCCC#N KVNRLNFWIYMESJ-UHFFFAOYSA-N 0.000 claims description 3
- YXDXXGXWFJCXEB-UHFFFAOYSA-N 2-furonitrile Chemical compound N#CC1=CC=CO1 YXDXXGXWFJCXEB-UHFFFAOYSA-N 0.000 claims description 2
- LAHDQCRTBCQHRL-UHFFFAOYSA-N C(C(C)C)(=O)N.C(C(C)C)#N Chemical compound C(C(C)C)(=O)N.C(C(C)C)#N LAHDQCRTBCQHRL-UHFFFAOYSA-N 0.000 claims description 2
- RENMDAKOXSCIGH-UHFFFAOYSA-N Chloroacetonitrile Chemical compound ClCC#N RENMDAKOXSCIGH-UHFFFAOYSA-N 0.000 claims description 2
- DFNYGALUNNFWKJ-UHFFFAOYSA-N aminoacetonitrile Chemical compound NCC#N DFNYGALUNNFWKJ-UHFFFAOYSA-N 0.000 claims description 2
- 230000036571 hydration Effects 0.000 claims description 2
- 238000002955 isolation Methods 0.000 claims description 2
- BSSNZUFKXJJCBG-OWOJBTEDSA-N (e)-but-2-enediamide Chemical compound NC(=O)\C=C\C(N)=O BSSNZUFKXJJCBG-OWOJBTEDSA-N 0.000 claims 1
- XXEPZEHTPKWESN-UHFFFAOYSA-N 2-methylprop-2-enamide;2-methylprop-2-enenitrile Chemical compound CC(=C)C#N.CC(=C)C(N)=O XXEPZEHTPKWESN-UHFFFAOYSA-N 0.000 claims 1
- WSGYTJNNHPZFKR-UHFFFAOYSA-N 3-hydroxypropanenitrile Chemical compound OCCC#N WSGYTJNNHPZFKR-UHFFFAOYSA-N 0.000 claims 1
- FBVNZZNSKBRXLU-UHFFFAOYSA-N C(CCC)#N.C(CCC)N Chemical compound C(CCC)#N.C(CCC)N FBVNZZNSKBRXLU-UHFFFAOYSA-N 0.000 claims 1
- SRAMKOXDWPBYAA-UHFFFAOYSA-N CCC#N.CCC(N)=O Chemical compound CCC#N.CCC(N)=O SRAMKOXDWPBYAA-UHFFFAOYSA-N 0.000 claims 1
- 210000000712 G cell Anatomy 0.000 claims 1
- KBVVMANFPYCWAO-UHFFFAOYSA-N acetamide;acetonitrile Chemical compound CC#N.CC(N)=O KBVVMANFPYCWAO-UHFFFAOYSA-N 0.000 claims 1
- HVAXLBWBBUSNJM-UHFFFAOYSA-N benzamide;benzonitrile Chemical compound N#CC1=CC=CC=C1.NC(=O)C1=CC=CC=C1 HVAXLBWBBUSNJM-UHFFFAOYSA-N 0.000 claims 1
- AGSPXMVUFBBBMO-UHFFFAOYSA-N beta-aminopropionitrile Chemical compound NCCC#N AGSPXMVUFBBBMO-UHFFFAOYSA-N 0.000 claims 1
- XEQABKABQVKQFY-UHFFFAOYSA-N butanediamide;butanedinitrile Chemical compound N#CCCC#N.NC(=O)CCC(N)=O XEQABKABQVKQFY-UHFFFAOYSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- WRIRWRKPLXCTFD-UHFFFAOYSA-N malonamide Chemical compound NC(=O)CC(N)=O WRIRWRKPLXCTFD-UHFFFAOYSA-N 0.000 claims 1
- UZDCCNLYFSOTDM-UHFFFAOYSA-N pentanamide;pentanenitrile Chemical compound CCCCC#N.CCCCC(N)=O UZDCCNLYFSOTDM-UHFFFAOYSA-N 0.000 claims 1
- TWNDNUUBEBLCNU-UHFFFAOYSA-N pyridine-2-carbonitrile;pyridine-3-carboxamide Chemical compound N#CC1=CC=CC=N1.NC(=O)C1=CC=CN=C1 TWNDNUUBEBLCNU-UHFFFAOYSA-N 0.000 claims 1
- IAHFWCOBPZCAEA-UHFFFAOYSA-N succinonitrile Chemical compound N#CCCC#N IAHFWCOBPZCAEA-UHFFFAOYSA-N 0.000 claims 1
- 230000000887 hydrating effect Effects 0.000 abstract description 2
- 230000000813 microbial effect Effects 0.000 abstract 2
- 238000003794 Gram staining Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 29
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 16
- 239000000203 mixture Substances 0.000 description 14
- 239000006285 cell suspension Substances 0.000 description 8
- 210000001822 immobilized cell Anatomy 0.000 description 7
- 238000004817 gas chromatography Methods 0.000 description 6
- 238000004445 quantitative analysis Methods 0.000 description 6
- 108090000790 Enzymes Proteins 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 4
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 4
- 239000001630 malic acid Substances 0.000 description 4
- 235000011090 malic acid Nutrition 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 239000001888 Peptone Substances 0.000 description 3
- 108010080698 Peptones Proteins 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 229940041514 candida albicans extract Drugs 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000005286 illumination Methods 0.000 description 3
- 235000019319 peptone Nutrition 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 239000012138 yeast extract Substances 0.000 description 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 2
- 239000011790 ferrous sulphate Substances 0.000 description 2
- 235000003891 ferrous sulphate Nutrition 0.000 description 2
- 239000001530 fumaric acid Substances 0.000 description 2
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
- MTPJEFOSTIKRSS-UHFFFAOYSA-N 3-(dimethylamino)propanenitrile Chemical compound CN(C)CCC#N MTPJEFOSTIKRSS-UHFFFAOYSA-N 0.000 description 1
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 description 1
- 241000186216 Corynebacterium Species 0.000 description 1
- 241000186145 Corynebacterium ammoniagenes Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 239000001744 Sodium fumarate Substances 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 150000003926 acrylamides Chemical class 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 description 1
- DNSISZSEWVHGLH-UHFFFAOYSA-N butanamide Chemical compound CCCC(N)=O DNSISZSEWVHGLH-UHFFFAOYSA-N 0.000 description 1
- SNCZNSNPXMPCGN-UHFFFAOYSA-N butanediamide Chemical compound NC(=O)CCC(N)=O SNCZNSNPXMPCGN-UHFFFAOYSA-N 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- MSJMDZAOKORVFC-SEPHDYHBSA-L disodium fumarate Chemical compound [Na+].[Na+].[O-]C(=O)\C=C\C([O-])=O MSJMDZAOKORVFC-SEPHDYHBSA-L 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229910000358 iron sulfate Inorganic materials 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 description 1
- NXPPAOGUKPJVDI-UHFFFAOYSA-N naphthalene-1,2-diol Chemical compound C1=CC=CC2=C(O)C(O)=CC=C21 NXPPAOGUKPJVDI-UHFFFAOYSA-N 0.000 description 1
- 229960003966 nicotinamide Drugs 0.000 description 1
- 235000005152 nicotinamide Nutrition 0.000 description 1
- 239000011570 nicotinamide Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000008055 phosphate buffer solution Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- QLNJFJADRCOGBJ-UHFFFAOYSA-N propionamide Chemical compound CCC(N)=O QLNJFJADRCOGBJ-UHFFFAOYSA-N 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229940005573 sodium fumarate Drugs 0.000 description 1
- 235000019294 sodium fumarate Nutrition 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical class [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58125588A JPS6019496A (ja) | 1983-07-12 | 1983-07-12 | 微生物によるアミド類の製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1530101A3 true SU1530101A3 (ru) | 1989-12-15 |
Family
ID=14913885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU843764662A SU1530101A3 (ru) | 1983-07-12 | 1984-07-11 | Способ получени амида |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4908313A (OSRAM) |
| EP (1) | EP0133927B1 (OSRAM) |
| JP (1) | JPS6019496A (OSRAM) |
| BR (1) | BR8403429A (OSRAM) |
| DE (1) | DE3479593D1 (OSRAM) |
| IL (1) | IL72370A (OSRAM) |
| SU (1) | SU1530101A3 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5937951B2 (ja) * | 1981-11-18 | 1984-09-12 | 秀明 山田 | アミドの生物学的製造法 |
| JPS61162195A (ja) * | 1985-01-11 | 1986-07-22 | Nitto Chem Ind Co Ltd | 微生物によるアミド類の製造法 |
| US5206158A (en) * | 1986-07-02 | 1993-04-27 | Gist-Brocades N.V. | Process for the preparation of difluorobenzamide |
| GB8616160D0 (en) * | 1986-07-02 | 1986-08-06 | Shell Int Research | Difluorobenzamide |
| DE69126762T2 (de) * | 1990-11-14 | 1997-10-23 | Nitto Chemical Industry Co Ltd | Biologisches Verfahren zur Herstellung von Alpha-Hydroxyamid und Alpha-Hydroxysäure |
| TW422882B (en) * | 1994-02-01 | 2001-02-21 | Sumitomo Chemical Co | Process for production of amide compounds using microorganism |
| US5599698A (en) * | 1994-12-27 | 1997-02-04 | Montefibre S.P.A. | Modified materials based on polyacrylonitrile and process for their production |
| GB9525372D0 (en) * | 1995-12-12 | 1996-02-14 | Allied Colloids Ltd | Enzymes, their preparation and their use in the production of ammonium acrylate |
| US5728556A (en) * | 1996-03-14 | 1998-03-17 | E. I. Du Pont De Nemours And Company | Production of ω-cyanocarboxamides from aliphatic α,ω-dinitriles using pseudomonas putida-derived biocatalysts |
| US5863750A (en) * | 1996-12-18 | 1999-01-26 | Cytec Tech Corp | Methods for the detoxification of nitrile and/or amide compounds |
| US6060265A (en) * | 1996-12-18 | 2000-05-09 | Cytec Technology Corporation | Methods for the detoxification of nitrile and/or amide compounds |
| US7300775B2 (en) * | 1999-12-29 | 2007-11-27 | Verenium Corporation | Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents |
| US7608445B1 (en) | 1999-12-29 | 2009-10-27 | Verenium Corporation | Nitrilases, nucleic acids encoding them and methods for making and using them |
| US7521216B2 (en) * | 1999-12-29 | 2009-04-21 | Verenium Corporation | Nitrilases and methods for making and using them |
| US20040014195A1 (en) * | 1999-12-29 | 2004-01-22 | Diversa Corporation | Nitrilases, nucleic acids encoding them and methods for making and using them |
| US7932064B2 (en) | 2002-06-13 | 2011-04-26 | Verenium Corporation | Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid |
| WO2008106662A2 (en) | 2007-03-01 | 2008-09-04 | Verenium Corporation | Nitrilases, nucleic acids encoding them and methods for making and using them |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB417863A (en) * | 1932-04-12 | 1934-10-11 | Paul Liebesny | A method of influencing technically useful micro-organisms, and ferments |
| DE2215113C3 (de) * | 1971-03-30 | 1975-01-02 | Univ Moskovsk | Verfahren zum Kultivieren von Mikroorganismen |
| US3880717A (en) * | 1971-03-30 | 1975-04-29 | Leonid Borisovich Rubin | Method of cultivating microorganisms |
| GB2018240B (en) * | 1978-03-29 | 1982-12-22 | Nitto Chemical Industry Co Ltd | Process for producing acrylamide or methacrylamide utilizing microoganisms |
| JPS5835077B2 (ja) * | 1979-05-02 | 1983-07-30 | 日東化学工業株式会社 | 微生物によるアクリルアミドまたはメタアクリルアミドの連続製造法 |
-
1983
- 1983-07-12 JP JP58125588A patent/JPS6019496A/ja active Granted
-
1984
- 1984-07-09 DE DE8484108024T patent/DE3479593D1/de not_active Expired
- 1984-07-09 EP EP84108024A patent/EP0133927B1/en not_active Expired
- 1984-07-10 BR BR8403429A patent/BR8403429A/pt not_active IP Right Cessation
- 1984-07-10 IL IL72370A patent/IL72370A/xx unknown
- 1984-07-11 SU SU843764662A patent/SU1530101A3/ru active
-
1987
- 1987-12-10 US US07/131,281 patent/US4908313A/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| Патент JP Г 17918/81, кл. С 12 Р 13/02, 19&1. Патент JP Г 38ll8/8l, кл. С 12 Р 13/02, 1981. * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL72370A0 (en) | 1984-11-30 |
| BR8403429A (pt) | 1985-06-25 |
| EP0133927B1 (en) | 1989-08-30 |
| JPH0235B2 (OSRAM) | 1990-01-05 |
| DE3479593D1 (en) | 1989-10-05 |
| US4908313A (en) | 1990-03-13 |
| JPS6019496A (ja) | 1985-01-31 |
| EP0133927A2 (en) | 1985-03-13 |
| IL72370A (en) | 1987-11-30 |
| EP0133927A3 (en) | 1986-05-14 |
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