SU1375137A3 - Способ получени гетероциклических соединений с конденсированным бензолом - Google Patents

Способ получени гетероциклических соединений с конденсированным бензолом Download PDF

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Publication number
SU1375137A3
SU1375137A3 SU853967801A SU3967801A SU1375137A3 SU 1375137 A3 SU1375137 A3 SU 1375137A3 SU 853967801 A SU853967801 A SU 853967801A SU 3967801 A SU3967801 A SU 3967801A SU 1375137 A3 SU1375137 A3 SU 1375137A3
Authority
SU
USSR - Soviet Union
Prior art keywords
group
singlet
propionyl
chloro
quinoline
Prior art date
Application number
SU853967801A
Other languages
English (en)
Russian (ru)
Inventor
Уеда Икуо
Сиокава Еуити
Манабе Такаси
Кацура Есуке
Original Assignee
Фудзисава Фармасьютикал Ко.,Лтд (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848427124A external-priority patent/GB8427124D0/en
Priority claimed from GB858513399A external-priority patent/GB8513399D0/en
Application filed by Фудзисава Фармасьютикал Ко.,Лтд (Фирма) filed Critical Фудзисава Фармасьютикал Ко.,Лтд (Фирма)
Application granted granted Critical
Publication of SU1375137A3 publication Critical patent/SU1375137A3/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
SU853967801A 1984-10-26 1985-10-25 Способ получени гетероциклических соединений с конденсированным бензолом SU1375137A3 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848427124A GB8427124D0 (en) 1984-10-26 1984-10-26 Benzene-fused heterocyclic compound
GB858513399A GB8513399D0 (en) 1985-05-28 1985-05-28 Heterocyclic compound

Publications (1)

Publication Number Publication Date
SU1375137A3 true SU1375137A3 (ru) 1988-02-15

Family

ID=26288380

Family Applications (1)

Application Number Title Priority Date Filing Date
SU853967801A SU1375137A3 (ru) 1984-10-26 1985-10-25 Способ получени гетероциклических соединений с конденсированным бензолом

Country Status (16)

Country Link
US (2) US4675324A (enExample)
EP (1) EP0180352B1 (enExample)
JP (1) JPH0649702B2 (enExample)
KR (1) KR860003259A (enExample)
CN (1) CN85108618A (enExample)
AT (1) ATE89825T1 (enExample)
AU (1) AU4855185A (enExample)
DE (1) DE3587362T2 (enExample)
DK (1) DK493185A (enExample)
ES (2) ES8702139A1 (enExample)
FI (1) FI853757A7 (enExample)
GR (1) GR852593B (enExample)
HU (1) HUT40124A (enExample)
NO (1) NO854275L (enExample)
PH (1) PH21213A (enExample)
SU (1) SU1375137A3 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839368A (en) * 1986-05-02 1989-06-13 Mochida Pharmaceutical Co., Ltd. 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
BR8806571A (pt) * 1987-04-09 1989-10-17 Du Pont Indazois substituidos inseticidas
JP2602037B2 (ja) * 1987-10-31 1997-04-23 持田製薬株式会社 1−アシル−2,3−ジヒドロ−4(1h)−キノリノン−4−オキシム誘導体、その製法およびそれらを主成分とする利尿、降圧、抗浮腫および腹水除去用医薬組成物
US5192768A (en) * 1990-09-14 1993-03-09 Kyowa Hakko Kogyo Co., Ltd. Pyrazoloquinoline derivatives
ATE360617T1 (de) 1994-06-15 2007-05-15 Otsuka Pharma Co Ltd Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatoren
US5865170A (en) * 1997-07-23 1999-02-02 Moles; Randall C. Customizable mouthpiece for scuba-divers
ATE353898T1 (de) * 2002-11-22 2007-03-15 Active Biotech Ab Pyrazolochinoline mit immunmodulierenderwirkung
EP1668008A4 (en) * 2003-08-28 2009-02-25 Nitromed Inc NITROSED AND NITROSYLATED DIETETIC COMPOUNDS, COMPOSITIONS AND APPLICATION METHODS
CA2597460A1 (en) * 2005-02-24 2006-08-31 Nitromed, Inc. Nitric oxide enhancing diuretic compounds, compositions and methods of use
CN101616908B (zh) 2006-12-29 2014-09-10 Abbvie德国有限责任两合公司 羧酰胺化合物及它们作为钙蛋白酶抑制剂的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2009079A1 (enExample) * 1968-05-22 1970-01-30 Sandoz Sa
US3624102A (en) * 1969-05-21 1971-11-30 Warner Lambert Co Substituted benzopyranopyrazoles
DE3068673D1 (en) * 1979-06-21 1984-08-30 Ciba Geigy Ag Pyrazolo-quinolines, processes for their production, and pharmaceutical compositions containing them
US4524146A (en) * 1982-12-08 1985-06-18 Ciba-Geigy Corporation Certain -2-heterocycle substituted pyrazoloquinolines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Обща органическа хими . Азотсодержащие гетероциклы. М.: Хими , 1985, т. 8, с. 477-478. *

Also Published As

Publication number Publication date
EP0180352B1 (en) 1993-05-26
FI853757L (fi) 1986-04-27
DK493185A (da) 1986-04-27
US4767780A (en) 1988-08-30
ES548205A0 (es) 1986-12-16
DE3587362T2 (de) 1993-09-09
JPS61112076A (ja) 1986-05-30
FI853757A7 (fi) 1986-04-27
US4675324A (en) 1987-06-23
FI853757A0 (fi) 1985-09-30
ES557041A0 (es) 1987-12-16
NO854275L (no) 1986-04-28
HUT40124A (en) 1986-11-28
DK493185D0 (da) 1985-10-25
ES8702139A1 (es) 1986-12-16
GR852593B (enExample) 1985-12-24
ES8801266A1 (es) 1987-12-16
DE3587362D1 (de) 1993-07-01
AU4855185A (en) 1986-05-01
KR860003259A (ko) 1986-05-21
CN85108618A (zh) 1986-08-27
ATE89825T1 (de) 1993-06-15
JPH0649702B2 (ja) 1994-06-29
EP0180352A3 (en) 1988-03-30
PH21213A (en) 1987-08-21
EP0180352A2 (en) 1986-05-07

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