SU1287521A1 - 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis - Google Patents
2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesisInfo
- Publication number
- SU1287521A1 SU1287521A1 SU3859898/04A SU3859898A SU1287521A1 SU 1287521 A1 SU1287521 A1 SU 1287521A1 SU 3859898/04 A SU3859898/04 A SU 3859898/04A SU 3859898 A SU3859898 A SU 3859898A SU 1287521 A1 SU1287521 A1 SU 1287521A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- dimethylaminopropyl
- tetramethyl
- diethyl
- synthesis
- antiiradiation
- Prior art date
Links
Abstract
FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: 1. Products: 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts of the general formulawhere a) HX - =2(CHSOH,; b) HX - 4 HCl showing antiiradiation activity. 2. Method of synthesis of 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts of the general formulawhere a) HX - =2CHSOH,; b) HX - 4 HCl. Mesoporphyrin-IX is treated with thionyl chloride and the prepared chloroanhydride interacts with dimethylamine. Formed mesoporphyrin-IX dimethylamide interacts with zinc acetate followed by reduction with lithium alumohydride of formed zinc complex and demetallation of the latter with hydrochloric acid. EFFECT: improved method of synthesis.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU3859898/04A SU1287521A1 (en) | 1985-01-10 | 1985-01-10 | 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU3859898/04A SU1287521A1 (en) | 1985-01-10 | 1985-01-10 | 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
SU1287521A1 true SU1287521A1 (en) | 1996-10-27 |
Family
ID=60542974
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU3859898/04A SU1287521A1 (en) | 1985-01-10 | 1985-01-10 | 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis |
Country Status (1)
Country | Link |
---|---|
SU (1) | SU1287521A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2506083C2 (en) * | 2008-05-23 | 2014-02-10 | Нэшнл Джуиш Хелт | Method of treating disorders associated with alkylating agent exposure |
-
1985
- 1985-01-10 SU SU3859898/04A patent/SU1287521A1/en active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2506083C2 (en) * | 2008-05-23 | 2014-02-10 | Нэшнл Джуиш Хелт | Method of treating disorders associated with alkylating agent exposure |
US11382895B2 (en) | 2008-05-23 | 2022-07-12 | National Jewish Health | Methods for treating injury associated with exposure to an alkylating species |
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