SU1287521A1 - 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis - Google Patents

2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis

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Publication number
SU1287521A1
SU1287521A1 SU3859898/04A SU3859898A SU1287521A1 SU 1287521 A1 SU1287521 A1 SU 1287521A1 SU 3859898/04 A SU3859898/04 A SU 3859898/04A SU 3859898 A SU3859898 A SU 3859898A SU 1287521 A1 SU1287521 A1 SU 1287521A1
Authority
SU
USSR - Soviet Union
Prior art keywords
dimethylaminopropyl
tetramethyl
diethyl
synthesis
antiiradiation
Prior art date
Application number
SU3859898/04A
Other languages
Russian (ru)
Inventor
Г.Б. Маравин
С.Д. Новосельцева
Г.В. Пономарев
Л.Т. Строганова
Т.Н. Тужилкова
Е.И. Ярцев
В.Г. Яшунский
Original Assignee
Г.Б. Маравин
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Г.Б. Маравин filed Critical Г.Б. Маравин
Priority to SU3859898/04A priority Critical patent/SU1287521A1/en
Application granted granted Critical
Publication of SU1287521A1 publication Critical patent/SU1287521A1/en

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Abstract

FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: 1. Products: 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts of the general formulawhere a) HX - =2(CHSOH,; b) HX - 4 HCl showing antiiradiation activity. 2. Method of synthesis of 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts of the general formulawhere a) HX - =2CHSOH,; b) HX - 4 HCl. Mesoporphyrin-IX is treated with thionyl chloride and the prepared chloroanhydride interacts with dimethylamine. Formed mesoporphyrin-IX dimethylamide interacts with zinc acetate followed by reduction with lithium alumohydride of formed zinc complex and demetallation of the latter with hydrochloric acid. EFFECT: improved method of synthesis.
SU3859898/04A 1985-01-10 1985-01-10 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis SU1287521A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU3859898/04A SU1287521A1 (en) 1985-01-10 1985-01-10 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU3859898/04A SU1287521A1 (en) 1985-01-10 1985-01-10 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis

Publications (1)

Publication Number Publication Date
SU1287521A1 true SU1287521A1 (en) 1996-10-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU3859898/04A SU1287521A1 (en) 1985-01-10 1985-01-10 2,7,12,18-tetramethyl-3,8-diethyl-13,17-di-(3-dimethylaminopropyl)-porphyrin salts showing antiiradiation activity and a method of their synthesis

Country Status (1)

Country Link
SU (1) SU1287521A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2506083C2 (en) * 2008-05-23 2014-02-10 Нэшнл Джуиш Хелт Method of treating disorders associated with alkylating agent exposure

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2506083C2 (en) * 2008-05-23 2014-02-10 Нэшнл Джуиш Хелт Method of treating disorders associated with alkylating agent exposure
US11382895B2 (en) 2008-05-23 2022-07-12 National Jewish Health Methods for treating injury associated with exposure to an alkylating species

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