ES8403860A1 - Derivatives of d-2-(6-methoxy-2-naphthyl)propionic acid having therapeutic activity, process for their preparation and medicaments containing them - Google Patents

Derivatives of d-2-(6-methoxy-2-naphthyl)propionic acid having therapeutic activity, process for their preparation and medicaments containing them

Info

Publication number
ES8403860A1
ES8403860A1 ES520623A ES520623A ES8403860A1 ES 8403860 A1 ES8403860 A1 ES 8403860A1 ES 520623 A ES520623 A ES 520623A ES 520623 A ES520623 A ES 520623A ES 8403860 A1 ES8403860 A1 ES 8403860A1
Authority
ES
Spain
Prior art keywords
naphthyl
methoxy
propionic acid
therapeutic activity
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES520623A
Other languages
Spanish (es)
Other versions
ES520623A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Isnardi Pietro & C SpA
Original Assignee
Isnardi Pietro & C SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isnardi Pietro & C SpA filed Critical Isnardi Pietro & C SpA
Publication of ES520623A0 publication Critical patent/ES520623A0/en
Publication of ES8403860A1 publication Critical patent/ES8403860A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The amide of d-2-(6-methoxy-2-naphthyl)propionic acid with p-aminobenzoic acid and organic and inorganic salts thereof display a pharmacological and therapeutic activity which is comparable with that of the active starting compound, but with decreased toxicity if the dose is kept the same.
ES520623A 1982-03-16 1983-03-15 Derivatives of d-2-(6-methoxy-2-naphthyl)propionic acid having therapeutic activity, process for their preparation and medicaments containing them Expired ES8403860A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20190/82A IT1150687B (en) 1982-03-16 1982-03-16 D-2- (6-METHOXY-2-NAFTYL) ACID DERIVATIVES THERAPEUTIC PROPIONIC, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
ES520623A0 ES520623A0 (en) 1984-04-01
ES8403860A1 true ES8403860A1 (en) 1984-04-01

Family

ID=11164574

Family Applications (1)

Application Number Title Priority Date Filing Date
ES520623A Expired ES8403860A1 (en) 1982-03-16 1983-03-15 Derivatives of d-2-(6-methoxy-2-naphthyl)propionic acid having therapeutic activity, process for their preparation and medicaments containing them

Country Status (6)

Country Link
KR (1) KR840003812A (en)
CH (1) CH660480A5 (en)
DE (1) DE3309258A1 (en)
ES (1) ES8403860A1 (en)
FR (1) FR2523577B1 (en)
IT (1) IT1150687B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505411A1 (en) * 1981-05-08 1982-11-12 Binder Adam DEVICE FOR RECOVERING WIND ENERGY
DE3668450D1 (en) * 1985-03-14 1990-03-01 Smithkline Dauelsberg 5-AMINOSALICYL ACID DERIVATIVES OF NON-STEROIDAL ANTI-FLAMMABLE ACIDS.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3978116A (en) * 1971-11-04 1976-08-31 Syntex Corporation 2-naphthyl acetic acid derivatives and compositions and methods thereof
IT1064700B (en) * 1976-07-28 1985-02-25 Pessina Raffaele PROCEDURE FOR THE PREPARATION OF THE ACID D.2.6 METHOXY 2 PROFIONIC NAFTYL
FR2388789A1 (en) * 1977-04-27 1978-11-24 Seuref Ag BENZOIC ACID DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
FR2416214A1 (en) * 1978-02-02 1979-08-31 Inst Rech Scient Irs DERIVATIVES OF NAPHTHYL-1 ACETIC ACID, THEIR METHOD OF PREPARATION AND THEIR THERAPEUTIC APPLICATION

Also Published As

Publication number Publication date
DE3309258C2 (en) 1990-10-04
ES520623A0 (en) 1984-04-01
KR840003812A (en) 1984-10-04
IT8220190A0 (en) 1982-03-16
DE3309258A1 (en) 1983-09-22
FR2523577A1 (en) 1983-09-23
IT1150687B (en) 1986-12-17
CH660480A5 (en) 1987-04-30
FR2523577B1 (en) 1986-10-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202