NO933237L - Absorbate of an excipient mixture and a non-solid active substance for the manufacture of pharmaceutical preparations - Google Patents

Absorbate of an excipient mixture and a non-solid active substance for the manufacture of pharmaceutical preparations

Info

Publication number
NO933237L
NO933237L NO933237A NO933237A NO933237L NO 933237 L NO933237 L NO 933237L NO 933237 A NO933237 A NO 933237A NO 933237 A NO933237 A NO 933237A NO 933237 L NO933237 L NO 933237L
Authority
NO
Norway
Prior art keywords
active substance
absorbate
manufacture
pharmaceutical preparations
solid active
Prior art date
Application number
NO933237A
Other languages
Norwegian (no)
Other versions
NO933237D0 (en
Inventor
Theophil Hornykiewytsch
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO933237D0 publication Critical patent/NO933237D0/en
Publication of NO933237L publication Critical patent/NO933237L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)

Abstract

Det er beskrevet et adsorbat Inneholdende et pyrldin- 2,4-dikarboksylsyre-N.K'-diamld som virksomt stoff, 10- 30 % høydisperst sillslumdloksyd, 50 til 70 % av et inert hjelpestoff og O til 30 % stivelse og eventuelt ytterligere tilsatsstoffer, og en fremgangsmåte for fremstilling av dette adsorbatet.An adsorbate containing a pyrldin-2,4-dicarboxylic acid N.K'-diamide is disclosed as an active substance, 10-30% high-dispersed herbicide, 50 to 70% of an inert excipient and 0 to 30% starch and any additional additives. and a process for preparing this adsorbate.

NO933237A 1992-09-11 1993-09-10 Absorbate of an excipient mixture and a non-solid active substance for the manufacture of pharmaceutical preparations NO933237L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4230371 1992-09-11

Publications (2)

Publication Number Publication Date
NO933237D0 NO933237D0 (en) 1993-09-10
NO933237L true NO933237L (en) 1994-03-14

Family

ID=6467712

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933237A NO933237L (en) 1992-09-11 1993-09-10 Absorbate of an excipient mixture and a non-solid active substance for the manufacture of pharmaceutical preparations

Country Status (13)

Country Link
EP (1) EP0587137A1 (en)
JP (1) JPH06192093A (en)
KR (1) KR940006583A (en)
AU (1) AU663000B2 (en)
CA (1) CA2105913A1 (en)
FI (1) FI933954A (en)
HU (1) HUT67577A (en)
IL (1) IL106953A0 (en)
MX (1) MX9305578A (en)
NO (1) NO933237L (en)
NZ (1) NZ248627A (en)
TW (1) TW222585B (en)
ZA (1) ZA936695B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0701434B1 (en) * 1993-06-04 2002-08-07 Warner-Lambert Company Preparations containing silicon dioxide to improve the taste thereof
US5626878A (en) * 1995-01-10 1997-05-06 Warner Lambert Company Reduction of electrostatic forces between magnesium trisilicate adsorbates
CN1335769A (en) * 1998-12-18 2002-02-13 艾博特公司 Controlled release formulation of divalproex sodium
MXPA06014894A (en) * 2004-06-28 2007-03-21 Lifecycle Pharma As Porous tablets as carriers for liquid formulations.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2879161A (en) * 1956-05-14 1959-03-24 American Cyanamid Co Stable dry powder compositions containing choline chloride and methods of preparing same
DE3409063A1 (en) * 1984-03-13 1985-09-19 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING FLOWABLE CHOLIN CHLORIDE-SILICONE POWDER
DE3924093A1 (en) * 1989-07-20 1991-02-07 Hoechst Ag N, N'-BIS (ALKOXY-ALKYL) -PYRIDINE-2,4-DICARBONESAUREDIAMIDES, METHOD FOR THE PRODUCTION AND USE THEREOF
DE4020570A1 (en) * 1990-06-28 1992-01-02 Hoechst Ag 2,4- AND 2,5-SUBSTITUTED PYRIDINE-N-OXIDES, METHOD FOR THE PRODUCTION AND USE THEREOF
GB9025251D0 (en) * 1990-11-20 1991-01-02 Solomon Montague C Nifedipine dosage forms

Also Published As

Publication number Publication date
MX9305578A (en) 1994-03-31
HU9302555D0 (en) 1993-11-29
JPH06192093A (en) 1994-07-12
NO933237D0 (en) 1993-09-10
HUT67577A (en) 1995-04-28
AU663000B2 (en) 1995-09-21
FI933954A (en) 1994-03-12
NZ248627A (en) 1995-01-27
TW222585B (en) 1994-04-21
KR940006583A (en) 1994-04-25
AU4626293A (en) 1994-03-17
ZA936695B (en) 1994-04-05
FI933954A0 (en) 1993-09-09
EP0587137A1 (en) 1994-03-16
IL106953A0 (en) 1993-12-28
CA2105913A1 (en) 1994-03-12

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