ES8203086A1 - 4-Methoxy-isophthalic Acid Picolylemide Monohydrate - Google Patents
4-Methoxy-isophthalic Acid Picolylemide MonohydrateInfo
- Publication number
- ES8203086A1 ES8203086A1 ES501470A ES501470A ES8203086A1 ES 8203086 A1 ES8203086 A1 ES 8203086A1 ES 501470 A ES501470 A ES 501470A ES 501470 A ES501470 A ES 501470A ES 8203086 A1 ES8203086 A1 ES 8203086A1
- Authority
- ES
- Spain
- Prior art keywords
- monohydrate
- methoxy
- picolylemide
- isophthalic acid
- picolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
N,N'-bis-(3-picolyl)-4-methoxy- isophthalamide provided in crystalline form as its monohydrate, is a stable chemical structure and shows a high pharmaceutical activity for the treatment of thromboembolic disorders.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT48494/80A IT1143942B (en) | 1980-04-23 | 1980-04-23 | PICOLYLAMIDE HYDRATED ISOPHTHALIC ACID WITH ANTI-AGGREGATING, ANTI-THROMBINIC AND ANTI-AGULANT PLASTIC ACTION AND PROCEDURE FOR ITS PREPARATION |
Publications (2)
Publication Number | Publication Date |
---|---|
ES501470A0 ES501470A0 (en) | 1982-02-16 |
ES8203086A1 true ES8203086A1 (en) | 1982-02-16 |
Family
ID=11266904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES501470A Expired ES8203086A1 (en) | 1980-04-23 | 1981-04-20 | 4-Methoxy-isophthalic Acid Picolylemide Monohydrate |
Country Status (23)
Country | Link |
---|---|
JP (1) | JPS6043063B2 (en) |
AT (1) | AT375645B (en) |
AU (1) | AU537921B2 (en) |
BE (1) | BE888528A (en) |
CA (1) | CA1129419A (en) |
CH (1) | CH649533A5 (en) |
DD (1) | DD158397A5 (en) |
DE (1) | DE3113150C2 (en) |
DK (1) | DK155735C (en) |
ES (1) | ES8203086A1 (en) |
FI (1) | FI74951C (en) |
FR (1) | FR2481283B1 (en) |
GB (1) | GB2080288B (en) |
IE (1) | IE51218B1 (en) |
IL (1) | IL62509A (en) |
IT (1) | IT1143942B (en) |
NL (1) | NL186860C (en) |
NO (1) | NO154193C (en) |
NZ (1) | NZ196677A (en) |
OA (1) | OA06795A (en) |
PT (1) | PT72899B (en) |
SE (1) | SE438674B (en) |
ZA (1) | ZA812362B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1214915B (en) * | 1985-10-10 | 1990-01-31 | Manetti & Roberts Italo Brit | 4-METHOXYISOPHTALIC ACID DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY IN THROMBOEMBOLIC DISORDERS AND PROCEDURE FOR ITS PREPARATION |
US5227492A (en) * | 1988-01-20 | 1993-07-13 | Yamanouchi Pharmaceutical Co., Ltd. | Diurea derivatives useful as medicaments and processes for the preparation thereof |
TW200900393A (en) * | 2007-05-21 | 2009-01-01 | Dybly Ag | Salts of picotamide |
CN111154113A (en) * | 2019-12-31 | 2020-05-15 | 肇庆学院 | Metal organic complex based on binuclear cobalt (II) and preparation method thereof |
CN111154114A (en) * | 2019-12-31 | 2020-05-15 | 肇庆学院 | Zinc (II) metal organic coordination compound based on 5-ethoxy isophthalic acid and preparation method thereof |
CN112159347B (en) * | 2020-10-27 | 2022-06-07 | 常州工程职业技术学院 | Preparation method of picolitamide |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL149810B (en) * | 1969-04-21 | 1976-06-15 | Lilly Co Eli | METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION BY CONTAINING CRYSTALLINE CEPHALEXIN IN A FORM SUITABLE FOR THERAPEUTIC ADMINISTRATION, FORMED PHARMACEUTICAL PREPARATIONS, AND METHOD OF PREPARING THE APPLICATION FOR THE EXISTING ABOVE. |
IT1016005B (en) * | 1970-07-01 | 1977-05-30 | Manetti & Roberts Italo Brit | PICOLYLAMIDES OF ISOPHTHALIC ACID 4 HYDROXIS AND ITS DERIVATIVES AND RELATIVE PREPARATION PROCEDURE |
US3973026A (en) * | 1975-02-05 | 1976-08-03 | Societa Italo-Britannica L. Manetti-H. Roberts & C. | Inhibitor of blood plate aggregation |
-
1980
- 1980-04-23 IT IT48494/80A patent/IT1143942B/en active Protection Beyond IP Right Term
-
1981
- 1981-03-27 IL IL62509A patent/IL62509A/en not_active IP Right Cessation
- 1981-03-27 SE SE8101963A patent/SE438674B/en not_active IP Right Cessation
- 1981-03-30 NZ NZ196677A patent/NZ196677A/en unknown
- 1981-04-01 DE DE3113150A patent/DE3113150C2/en not_active Expired
- 1981-04-07 CH CH2531/81A patent/CH649533A5/en not_active IP Right Cessation
- 1981-04-08 AU AU69310/81A patent/AU537921B2/en not_active Ceased
- 1981-04-09 IE IE808/81A patent/IE51218B1/en not_active IP Right Cessation
- 1981-04-09 ZA ZA00812362A patent/ZA812362B/en unknown
- 1981-04-10 AT AT0166481A patent/AT375645B/en not_active IP Right Cessation
- 1981-04-14 CA CA375,430A patent/CA1129419A/en not_active Expired
- 1981-04-20 ES ES501470A patent/ES8203086A1/en not_active Expired
- 1981-04-21 DK DK177281A patent/DK155735C/en not_active IP Right Cessation
- 1981-04-21 PT PT72899A patent/PT72899B/en not_active IP Right Cessation
- 1981-04-22 NO NO811360A patent/NO154193C/en unknown
- 1981-04-22 FI FI811257A patent/FI74951C/en not_active IP Right Cessation
- 1981-04-22 JP JP56061120A patent/JPS6043063B2/en not_active Expired
- 1981-04-22 DD DD81229409A patent/DD158397A5/en not_active IP Right Cessation
- 1981-04-22 GB GB8112454A patent/GB2080288B/en not_active Expired
- 1981-04-23 BE BE2/59122A patent/BE888528A/en not_active IP Right Cessation
- 1981-04-23 OA OA57386A patent/OA06795A/en unknown
- 1981-04-23 FR FR8108501A patent/FR2481283B1/fr not_active Expired
- 1981-04-23 NL NLAANVRAGE8102016,A patent/NL186860C/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010301 |