JPS5379856A - Preparation of optical active 1-methyl-2-(beta-hydroxyethyl)pyrrplidive - Google Patents
Preparation of optical active 1-methyl-2-(beta-hydroxyethyl)pyrrplidiveInfo
- Publication number
- JPS5379856A JPS5379856A JP15292676A JP15292676A JPS5379856A JP S5379856 A JPS5379856 A JP S5379856A JP 15292676 A JP15292676 A JP 15292676A JP 15292676 A JP15292676 A JP 15292676A JP S5379856 A JPS5379856 A JP S5379856A
- Authority
- JP
- Japan
- Prior art keywords
- pyrrplidive
- hydroxyethyl
- beta
- methyl
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pyrrole Compounds (AREA)
Abstract
PURPOSE: To prepare the title cpd., useful as intermediates for pharmaceuticals, by reaction of the dl isomer of the title cpd. with optical active N-benzoyl-cis-2aminocyclocarboxylic acid chloride as a resolving agent, followed by optical resolution and hydrolysis.
COPYRIGHT: (C)1978,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15292676A JPS5379856A (en) | 1976-12-21 | 1976-12-21 | Preparation of optical active 1-methyl-2-(beta-hydroxyethyl)pyrrplidive |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15292676A JPS5379856A (en) | 1976-12-21 | 1976-12-21 | Preparation of optical active 1-methyl-2-(beta-hydroxyethyl)pyrrplidive |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5379856A true JPS5379856A (en) | 1978-07-14 |
Family
ID=15551151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15292676A Pending JPS5379856A (en) | 1976-12-21 | 1976-12-21 | Preparation of optical active 1-methyl-2-(beta-hydroxyethyl)pyrrplidive |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5379856A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008037865A (en) * | 2006-07-14 | 2008-02-21 | Nagasaki Univ | Asymmetric esterification reaction of n-protected amino alcohol compound using optically active bisoxazoline-copper complex as asymmetric catalyst |
CN111087337A (en) * | 2019-11-19 | 2020-05-01 | 山东科源制药股份有限公司 | Method for splitting chloromalastine fumarate intermediate |
-
1976
- 1976-12-21 JP JP15292676A patent/JPS5379856A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008037865A (en) * | 2006-07-14 | 2008-02-21 | Nagasaki Univ | Asymmetric esterification reaction of n-protected amino alcohol compound using optically active bisoxazoline-copper complex as asymmetric catalyst |
CN111087337A (en) * | 2019-11-19 | 2020-05-01 | 山东科源制药股份有限公司 | Method for splitting chloromalastine fumarate intermediate |
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