SU1048982A3 - Способ получени замещенных динитрилов малоновой кислоты - Google Patents
Способ получени замещенных динитрилов малоновой кислоты Download PDFInfo
- Publication number
- SU1048982A3 SU1048982A3 SU792847575A SU2847575A SU1048982A3 SU 1048982 A3 SU1048982 A3 SU 1048982A3 SU 792847575 A SU792847575 A SU 792847575A SU 2847575 A SU2847575 A SU 2847575A SU 1048982 A3 SU1048982 A3 SU 1048982A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- malonic acid
- substituted
- dinitriles
- temperature
- reactor
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 22
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title claims abstract description 8
- WEVYAHXRMPXWCK-UHFFFAOYSA-N methyl cyanide Natural products CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims abstract description 10
- QPJDMGCKMHUXFD-UHFFFAOYSA-N cyanogen chloride Chemical class ClC#N QPJDMGCKMHUXFD-UHFFFAOYSA-N 0.000 claims abstract description 5
- 150000007960 acetonitrile Chemical class 0.000 claims abstract description 3
- 239000000460 chlorine Substances 0.000 claims description 5
- 229910052801 chlorine Inorganic materials 0.000 claims description 5
- 238000004821 distillation Methods 0.000 claims description 4
- 230000003993 interaction Effects 0.000 claims description 3
- 239000000376 reactant Substances 0.000 claims description 3
- 125000001309 chloro group Chemical group Cl* 0.000 claims description 2
- 238000001816 cooling Methods 0.000 claims description 2
- 229910052731 fluorine Chemical group 0.000 claims description 2
- 239000011737 fluorine Chemical group 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical group [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract 1
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 12
- SUSQOBVLVYHIEX-UHFFFAOYSA-N phenylacetonitrile Chemical compound N#CCC1=CC=CC=C1 SUSQOBVLVYHIEX-UHFFFAOYSA-N 0.000 description 6
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- WWYDYZMNFQIYPT-UHFFFAOYSA-N ru78191 Chemical compound OC(=O)C(C(O)=O)C1=CC=CC=C1 WWYDYZMNFQIYPT-UHFFFAOYSA-N 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 239000002253 acid Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000011261 inert gas Substances 0.000 description 2
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 239000010453 quartz Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 150000007656 barbituric acids Chemical class 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/04—Preparation of carboxylic acid nitriles by reaction of cyanogen halides, e.g. ClCN, with organic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782854197 DE2854197A1 (de) | 1978-12-15 | 1978-12-15 | Verfahren zur herstellung von substituierten malonsaeuredinitrilen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1048982A3 true SU1048982A3 (ru) | 1983-10-15 |
Family
ID=6057290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU792847575A SU1048982A3 (ru) | 1978-12-15 | 1979-12-06 | Способ получени замещенных динитрилов малоновой кислоты |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5583742A (it) |
| AT (1) | AT362774B (it) |
| BE (1) | BE880557A (it) |
| CH (1) | CH641442A5 (it) |
| DE (1) | DE2854197A1 (it) |
| FR (1) | FR2444027A1 (it) |
| GB (1) | GB2037286B (it) |
| IT (1) | IT7951079A0 (it) |
| NL (1) | NL7907361A (it) |
| SU (1) | SU1048982A3 (it) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1173479A (en) * | 1966-11-28 | 1969-12-10 | Little Inc A | Improvements in method for Synthesizing Malononitrile |
-
1978
- 1978-12-15 DE DE19782854197 patent/DE2854197A1/de not_active Withdrawn
-
1979
- 1979-10-03 NL NL7907361A patent/NL7907361A/nl not_active Application Discontinuation
- 1979-11-19 FR FR7928483A patent/FR2444027A1/fr active Granted
- 1979-12-06 SU SU792847575A patent/SU1048982A3/ru active
- 1979-12-07 GB GB7942396A patent/GB2037286B/en not_active Expired
- 1979-12-11 BE BE6/47031A patent/BE880557A/fr not_active IP Right Cessation
- 1979-12-13 IT IT7951079A patent/IT7951079A0/it unknown
- 1979-12-14 AT AT0789479A patent/AT362774B/de active
- 1979-12-14 CH CH1111979A patent/CH641442A5/de not_active IP Right Cessation
- 1979-12-15 JP JP16220279A patent/JPS5583742A/ja active Pending
Non-Patent Citations (1)
| Title |
|---|
| 1. RobertА. Crimn et al. Phcnvlacctonitriles and Cyanogen Chloride,- Industrial and Engineering Chemistry Product Research and Development, 1975, 14, p. 158-161 (прототип) . * |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2854197A1 (de) | 1980-07-03 |
| CH641442A5 (de) | 1984-02-29 |
| NL7907361A (nl) | 1980-06-17 |
| FR2444027B1 (it) | 1984-01-27 |
| GB2037286B (en) | 1983-04-13 |
| AT362774B (de) | 1981-06-10 |
| ATA789479A (de) | 1980-11-15 |
| JPS5583742A (en) | 1980-06-24 |
| IT7951079A0 (it) | 1979-12-13 |
| BE880557A (fr) | 1980-06-11 |
| GB2037286A (en) | 1980-07-09 |
| FR2444027A1 (fr) | 1980-07-11 |
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