SU1005664A3 - Способ получени производных цефалоспорина или их солей с щелочными металлами - Google Patents
Способ получени производных цефалоспорина или их солей с щелочными металлами Download PDFInfo
- Publication number
- SU1005664A3 SU1005664A3 SU802921249A SU2921249A SU1005664A3 SU 1005664 A3 SU1005664 A3 SU 1005664A3 SU 802921249 A SU802921249 A SU 802921249A SU 2921249 A SU2921249 A SU 2921249A SU 1005664 A3 SU1005664 A3 SU 1005664A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- amino
- solution
- acid
- pyridazinyl
- thiazolyl
- Prior art date
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 208000008423 pleurisy Diseases 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 125000004941 pyridazin-5-yl group Chemical group N1=NC=CC(=C1)* 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 201000009890 sinusitis Diseases 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 125000004665 trialkylsilyl group Chemical group 0.000 description 1
- LZTRCELOJRDYMQ-UHFFFAOYSA-N triphenylmethanol Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(O)C1=CC=CC=C1 LZTRCELOJRDYMQ-UHFFFAOYSA-N 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
- C07C59/21—Saturated compounds having only one carboxyl group and containing keto groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7916376 | 1979-05-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1005664A3 true SU1005664A3 (ru) | 1983-03-15 |
Family
ID=10505086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU802921249A SU1005664A3 (ru) | 1979-05-11 | 1980-05-08 | Способ получени производных цефалоспорина или их солей с щелочными металлами |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4331666A (enExample) |
| JP (1) | JPS55151594A (enExample) |
| AT (1) | AT368512B (enExample) |
| AU (1) | AU530638B2 (enExample) |
| BE (1) | BE883209A (enExample) |
| CA (1) | CA1148939A (enExample) |
| CS (1) | CS219277B2 (enExample) |
| DE (1) | DE3015389A1 (enExample) |
| DK (1) | DK191080A (enExample) |
| ES (1) | ES8104307A1 (enExample) |
| FI (1) | FI801517A7 (enExample) |
| FR (1) | FR2456109A1 (enExample) |
| GB (1) | GB2053896B (enExample) |
| GR (1) | GR67280B (enExample) |
| IL (1) | IL59791A0 (enExample) |
| IT (1) | IT1195268B (enExample) |
| LU (1) | LU82429A1 (enExample) |
| NL (1) | NL8002690A (enExample) |
| NO (1) | NO801400L (enExample) |
| NZ (1) | NZ193615A (enExample) |
| PH (1) | PH17085A (enExample) |
| PT (1) | PT71220A (enExample) |
| SE (1) | SE8003429L (enExample) |
| SU (1) | SU1005664A3 (enExample) |
| ZA (1) | ZA802393B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2945248A1 (de) * | 1978-11-13 | 1980-05-22 | Fujisawa Pharmaceutical Co | Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel |
| US4499088A (en) * | 1983-01-04 | 1985-02-12 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| JPS60142987A (ja) * | 1983-12-29 | 1985-07-29 | Mochida Pharmaceut Co Ltd | セフアロスポリン誘導体 |
| DE150507T1 (de) * | 1983-12-29 | 1987-02-26 | Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo | Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate. |
| NZ215527A (en) * | 1985-04-01 | 1989-06-28 | Mochida Pharm Co Ltd | Cephalosporin derivatives and pharmaceutical compositions |
| US4840945A (en) * | 1985-04-01 | 1989-06-20 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| EP0359291A1 (en) * | 1985-04-01 | 1990-03-21 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| EP0225634B1 (en) * | 1985-12-13 | 1994-04-06 | Takeda Chemical Industries, Ltd. | Antibacterial compounds, their production and use |
| US4880798A (en) * | 1986-11-25 | 1989-11-14 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| JPS63132893A (ja) * | 1986-11-25 | 1988-06-04 | Mochida Pharmaceut Co Ltd | 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤 |
| GB8805642D0 (en) * | 1988-03-09 | 1988-04-07 | Fujisawa Pharmaceutical Co | New cephem compounds & processes for preparation thereof |
| EP0333082A3 (en) * | 1988-03-15 | 1991-05-02 | Takeda Chemical Industries, Ltd. | Cephem compounds, their production and use |
| WO2023250017A1 (en) * | 2022-06-21 | 2023-12-28 | Ohio State Innovation Foundation | Compounds for treating infections |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1075277B (it) * | 1977-02-11 | 1985-04-22 | Erba Carlo Spa | Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione |
| FR2345153A1 (fr) * | 1976-03-25 | 1977-10-21 | Roussel Uclaf | Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
| BE878514A (fr) * | 1978-09-04 | 1980-02-29 | Fujisawa Pharmaceutical Co | Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne |
| DE2760484C2 (enExample) * | 1976-04-14 | 1992-12-03 | Takeda Chemical Industries, Ltd., Osaka, Jp | |
| US4061861A (en) * | 1976-06-21 | 1977-12-06 | Eli Lilly And Company | 7-[α-(2,3-DIHYDRO-2-OXO-1H-benzimidazol-1-ylcarbonyl-amino)arylacetamido]cephalosporins |
| DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| DE2716677C2 (de) * | 1977-04-15 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Cephemderivate und Verfahren zu ihrer Herstellung |
| FR2387235A1 (fr) * | 1978-01-23 | 1978-11-10 | Fujisawa Pharmaceutical Co | Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne |
| US4268509A (en) * | 1978-07-10 | 1981-05-19 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds and processes for preparation thereof |
| JPS5511600A (en) * | 1978-07-10 | 1980-01-26 | Fujisawa Pharmaceut Co Ltd | Cephem compound, its salt, their preparation and remedy and prophylactic for microbism containing mainly the same |
-
1980
- 1980-04-08 US US06/138,338 patent/US4331666A/en not_active Expired - Lifetime
- 1980-04-09 IL IL59791A patent/IL59791A0/xx unknown
- 1980-04-14 AU AU57440/80A patent/AU530638B2/en not_active Ceased
- 1980-04-16 GB GB8012573A patent/GB2053896B/en not_active Expired
- 1980-04-18 PH PH23919A patent/PH17085A/en unknown
- 1980-04-21 ZA ZA00802393A patent/ZA802393B/xx unknown
- 1980-04-22 DE DE19803015389 patent/DE3015389A1/de not_active Ceased
- 1980-04-30 DK DK191080A patent/DK191080A/da not_active Application Discontinuation
- 1980-05-03 GR GR61857A patent/GR67280B/el unknown
- 1980-05-05 NZ NZ193615A patent/NZ193615A/xx unknown
- 1980-05-06 IT IT21822/80A patent/IT1195268B/it active
- 1980-05-07 CS CS803212A patent/CS219277B2/cs unknown
- 1980-05-07 SE SE8003429A patent/SE8003429L/xx not_active Application Discontinuation
- 1980-05-08 SU SU802921249A patent/SU1005664A3/ru active
- 1980-05-09 NO NO801400A patent/NO801400L/no unknown
- 1980-05-09 BE BE0/200542A patent/BE883209A/fr not_active IP Right Cessation
- 1980-05-09 NL NL8002690A patent/NL8002690A/nl not_active Application Discontinuation
- 1980-05-09 CA CA000351677A patent/CA1148939A/en not_active Expired
- 1980-05-09 LU LU82429A patent/LU82429A1/fr unknown
- 1980-05-09 AT AT0249680A patent/AT368512B/de not_active IP Right Cessation
- 1980-05-09 FI FI801517A patent/FI801517A7/fi not_active Application Discontinuation
- 1980-05-09 PT PT71220A patent/PT71220A/pt unknown
- 1980-05-09 FR FR8010488A patent/FR2456109A1/fr active Granted
- 1980-05-10 JP JP6126980A patent/JPS55151594A/ja active Pending
- 1980-05-10 ES ES491379A patent/ES8104307A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2456109A1 (fr) | 1980-12-05 |
| ATA249680A (de) | 1982-02-15 |
| LU82429A1 (fr) | 1980-07-31 |
| AU5744080A (en) | 1980-11-13 |
| GB2053896B (en) | 1983-04-07 |
| CA1148939A (en) | 1983-06-28 |
| IL59791A0 (en) | 1980-06-30 |
| GR67280B (enExample) | 1981-06-26 |
| JPS55151594A (en) | 1980-11-26 |
| FI801517A7 (fi) | 1980-11-12 |
| NZ193615A (en) | 1982-02-23 |
| ZA802393B (en) | 1981-04-29 |
| IT8021822A0 (it) | 1980-05-06 |
| AT368512B (de) | 1982-10-25 |
| CS219277B2 (en) | 1983-03-25 |
| DK191080A (da) | 1980-11-12 |
| DE3015389A1 (de) | 1980-11-20 |
| FR2456109B1 (enExample) | 1983-12-16 |
| ES491379A0 (es) | 1981-04-01 |
| IT1195268B (it) | 1988-10-12 |
| ES8104307A1 (es) | 1981-04-01 |
| AU530638B2 (en) | 1983-07-21 |
| NO801400L (no) | 1980-11-12 |
| BE883209A (fr) | 1980-11-10 |
| US4331666A (en) | 1982-05-25 |
| NL8002690A (nl) | 1980-11-13 |
| PT71220A (en) | 1980-06-01 |
| PH17085A (en) | 1984-05-24 |
| SE8003429L (sv) | 1980-11-12 |
| GB2053896A (en) | 1981-02-11 |
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