SMT201500056B - Derivati 4-(metilamminofenossi)piridin-3-il benzammidici per il trattamento del cancro - Google Patents

Derivati 4-(metilamminofenossi)piridin-3-il benzammidici per il trattamento del cancro

Info

Publication number
SMT201500056B
SMT201500056B SM201500056T SM201500056T SMT201500056B SM T201500056 B SMT201500056 B SM T201500056B SM 201500056 T SM201500056 T SM 201500056T SM 201500056 T SM201500056 T SM 201500056T SM T201500056 B SMT201500056 B SM T201500056B
Authority
SM
San Marino
Prior art keywords
methylaminophenoxy
pyridin
cancer treatment
benzamide derivatives
benzamide
Prior art date
Application number
SM201500056T
Other languages
English (en)
Inventor
Yutaka Kojima
Takumi Sumida
Makoto Sakamoto
Kazuya Yamaguchi
Yuki Terauchi
Masamichi Shirakura
Yasuo Harada
Takashi Makagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SMT201500056B publication Critical patent/SMT201500056B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/76Nitrogen atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SM201500056T 2010-10-04 2015-03-09 Derivati 4-(metilamminofenossi)piridin-3-il benzammidici per il trattamento del cancro SMT201500056B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38939310P 2010-10-04 2010-10-04
PCT/JP2011/073165 WO2012046825A1 (en) 2010-10-04 2011-10-03 4- (methylaminophenoxy) pyrdin- 3 - yl - benzamide derivatives for treating cancer

Publications (1)

Publication Number Publication Date
SMT201500056B true SMT201500056B (it) 2015-05-05

Family

ID=44872549

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500056T SMT201500056B (it) 2010-10-04 2015-03-09 Derivati 4-(metilamminofenossi)piridin-3-il benzammidici per il trattamento del cancro

Country Status (29)

Country Link
US (7) US8946437B2 (it)
EP (1) EP2624833B1 (it)
JP (1) JP5715690B2 (it)
KR (1) KR101797797B1 (it)
CN (1) CN103189061B (it)
AR (1) AR083287A1 (it)
AU (1) AU2011313236B2 (it)
BR (1) BR112013007841B1 (it)
CA (1) CA2813153C (it)
CO (1) CO6660459A2 (it)
DK (1) DK2624833T3 (it)
EA (1) EA021627B1 (it)
ES (1) ES2526574T3 (it)
HK (1) HK1187540A1 (it)
HR (1) HRP20141237T1 (it)
IL (1) IL225520A (it)
MX (1) MX2013003589A (it)
MY (1) MY157563A (it)
NZ (1) NZ609151A (it)
PL (1) PL2624833T3 (it)
PT (1) PT2624833E (it)
RS (1) RS53749B1 (it)
SG (1) SG189146A1 (it)
SI (1) SI2624833T1 (it)
SM (1) SMT201500056B (it)
TW (1) TWI526431B (it)
UA (1) UA110037C2 (it)
WO (1) WO2012046825A1 (it)
ZA (1) ZA201302332B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2624833T1 (sl) * 2010-10-04 2015-03-31 Otsuka Pharmaceutical Co., Ltd. Derivati 4-(metilaminofenoksi)piridin-3-il-benzamida za zdravljenje raka
JP6066806B2 (ja) * 2012-04-03 2017-01-25 大塚製薬株式会社 医薬
TW202102216A (zh) * 2019-03-25 2021-01-16 日商大塚製藥股份有限公司 抗腫瘤組合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
JP2001089412A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ベンゼン誘導体またはその医薬的に許容される塩
CN1993339B (zh) 2004-08-06 2013-05-22 大塚制药株式会社 芳香化合物
KR101157004B1 (ko) * 2005-12-05 2012-07-09 오쓰까 세이야꾸 가부시키가이샤 항종양제로서의 디아릴에테르 유도체
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
SI2624833T1 (sl) * 2010-10-04 2015-03-31 Otsuka Pharmaceutical Co., Ltd. Derivati 4-(metilaminofenoksi)piridin-3-il-benzamida za zdravljenje raka
TW202102216A (zh) * 2019-03-25 2021-01-16 日商大塚製藥股份有限公司 抗腫瘤組合物

Also Published As

Publication number Publication date
CO6660459A2 (es) 2013-04-30
US20210017134A1 (en) 2021-01-21
SG189146A1 (en) 2013-05-31
HK1187540A1 (en) 2014-04-11
PT2624833E (pt) 2014-12-26
AR083287A1 (es) 2013-02-13
CA2813153A1 (en) 2012-04-12
TWI526431B (zh) 2016-03-21
MY157563A (en) 2016-06-30
PL2624833T3 (pl) 2015-05-29
JP5715690B2 (ja) 2015-05-13
EP2624833A1 (en) 2013-08-14
US20230139808A1 (en) 2023-05-04
EA201390323A1 (ru) 2013-09-30
KR101797797B1 (ko) 2017-11-14
US20200031773A1 (en) 2020-01-30
AU2011313236B2 (en) 2016-05-19
EA021627B1 (ru) 2015-07-30
NZ609151A (en) 2015-01-30
US8946437B2 (en) 2015-02-03
RS53749B1 (en) 2015-06-30
JP2013538785A (ja) 2013-10-17
TW201307289A (zh) 2013-02-16
US20130267565A1 (en) 2013-10-10
EP2624833B1 (en) 2014-12-10
SI2624833T1 (sl) 2015-03-31
IL225520A (en) 2016-05-31
US20180265471A1 (en) 2018-09-20
BR112013007841B1 (pt) 2020-03-03
ZA201302332B (en) 2014-07-30
CN103189061A (zh) 2013-07-03
DK2624833T3 (en) 2015-01-05
UA110037C2 (uk) 2015-11-10
CN103189061B (zh) 2015-09-02
ES2526574T3 (es) 2015-01-13
AU2011313236A1 (en) 2013-04-18
IL225520A0 (en) 2013-06-27
BR112013007841A2 (pt) 2016-06-07
US20170298023A1 (en) 2017-10-19
KR20130121826A (ko) 2013-11-06
US20150105432A1 (en) 2015-04-16
WO2012046825A1 (en) 2012-04-12
MX2013003589A (es) 2013-06-24
CA2813153C (en) 2019-01-15
HRP20141237T1 (hr) 2015-02-13

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