SK5032000A3 - A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity, pharmaceutical composition containing the same, use thereof and intermediates - Google Patents
A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity, pharmaceutical composition containing the same, use thereof and intermediates Download PDFInfo
- Publication number
- SK5032000A3 SK5032000A3 SK503-2000A SK5032000A SK5032000A3 SK 5032000 A3 SK5032000 A3 SK 5032000A3 SK 5032000 A SK5032000 A SK 5032000A SK 5032000 A3 SK5032000 A3 SK 5032000A3
- Authority
- SK
- Slovakia
- Prior art keywords
- formula
- geneseroline
- group
- acid
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002299 IT1295309B1 (it) | 1997-10-10 | 1997-10-10 | Procedimento per la preparazione di amminocarbonil derivati di geneserolina |
| IT002300 IT1295310B1 (it) | 1997-10-10 | 1997-10-10 | Amminocarbonil derivati di geneserolina ad attivita' anticolinesterasica selettiva a livello cerebrale |
| PCT/EP1998/006377 WO1999019329A1 (en) | 1997-10-10 | 1998-10-07 | A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK5032000A3 true SK5032000A3 (en) | 2000-10-09 |
Family
ID=26331547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK503-2000A SK5032000A3 (en) | 1997-10-10 | 1998-10-07 | A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity, pharmaceutical composition containing the same, use thereof and intermediates |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6297237B1 (ru) |
| EP (1) | EP1023297A1 (ru) |
| KR (1) | KR20010015714A (ru) |
| CN (1) | CN1278264A (ru) |
| AR (1) | AR018511A1 (ru) |
| AU (1) | AU750964B2 (ru) |
| BR (1) | BR9815237A (ru) |
| CA (1) | CA2274658A1 (ru) |
| EA (1) | EA003192B1 (ru) |
| HU (1) | HUP0003747A3 (ru) |
| IL (1) | IL135399A0 (ru) |
| NZ (1) | NZ503773A (ru) |
| PL (1) | PL339761A1 (ru) |
| SK (1) | SK5032000A3 (ru) |
| TR (1) | TR200000951T2 (ru) |
| TW (1) | TW490467B (ru) |
| WO (1) | WO1999019329A1 (ru) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1109003B (it) | 1977-09-20 | 1985-12-16 | Univ Firenze | Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo |
| US4791107A (en) | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| IT1251166B (it) * | 1991-08-09 | 1995-05-04 | Chiesi Farma Spa | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
| US5571929A (en) | 1994-12-07 | 1996-11-05 | The United States Of America As Represented By The Department Of Health And Human Services | Resolution and reduction of physostigmine intermediates and derivatives |
| US5677457A (en) * | 1996-12-19 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseroline ethers |
-
1998
- 1998-10-07 BR BR9815237-8A patent/BR9815237A/pt not_active IP Right Cessation
- 1998-10-07 WO PCT/EP1998/006377 patent/WO1999019329A1/en not_active Application Discontinuation
- 1998-10-07 IL IL13539998A patent/IL135399A0/xx unknown
- 1998-10-07 PL PL98339761A patent/PL339761A1/xx unknown
- 1998-10-07 HU HU0003747A patent/HUP0003747A3/hu unknown
- 1998-10-07 US US09/319,693 patent/US6297237B1/en not_active Expired - Fee Related
- 1998-10-07 CN CN98810683A patent/CN1278264A/zh active Pending
- 1998-10-07 NZ NZ503773A patent/NZ503773A/en unknown
- 1998-10-07 SK SK503-2000A patent/SK5032000A3/sk unknown
- 1998-10-07 EP EP98954370A patent/EP1023297A1/en not_active Withdrawn
- 1998-10-07 TR TR2000/00951T patent/TR200000951T2/xx unknown
- 1998-10-07 KR KR1020007003805A patent/KR20010015714A/ko not_active Application Discontinuation
- 1998-10-07 AU AU11516/99A patent/AU750964B2/en not_active Ceased
- 1998-10-07 EA EA200000300A patent/EA003192B1/ru not_active IP Right Cessation
- 1998-10-07 CA CA002274658A patent/CA2274658A1/en not_active Abandoned
- 1998-10-09 AR ARP980105062A patent/AR018511A1/es unknown
- 1998-10-23 TW TW087117571A patent/TW490467B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| BR9815237A (pt) | 2000-10-31 |
| NZ503773A (en) | 2002-05-31 |
| HUP0003747A3 (en) | 2001-12-28 |
| KR20010015714A (ko) | 2001-02-26 |
| WO1999019329A1 (en) | 1999-04-22 |
| IL135399A0 (en) | 2001-05-20 |
| EA003192B1 (ru) | 2003-02-27 |
| TW490467B (en) | 2002-06-11 |
| CN1278264A (zh) | 2000-12-27 |
| HUP0003747A2 (hu) | 2001-10-28 |
| AU750964B2 (en) | 2002-08-01 |
| EP1023297A1 (en) | 2000-08-02 |
| AU1151699A (en) | 1999-05-03 |
| AR018511A1 (es) | 2001-11-28 |
| US6297237B1 (en) | 2001-10-02 |
| PL339761A1 (en) | 2001-01-02 |
| EA200000300A1 (ru) | 2000-12-25 |
| TR200000951T2 (tr) | 2000-07-21 |
| CA2274658A1 (en) | 1999-04-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPH0529399B2 (ru) | ||
| US20040171828A1 (en) | Derivatives of pyrimido[6,1-a]isoquinolin-4-one | |
| KR100225927B1 (ko) | 콜린에스테라제 저해제로서의 제네세린 유도체 | |
| CH663023A5 (fr) | Derives de la furo-(3,4-c)-pyridine substitues en position 6, un procede pour leur preparation et compositions therapeutiques a base de ces derives. | |
| EP0521768B1 (fr) | Nouveaux dérivés de triazolopyrimidine antagonistes des récepteurs à l'angiotensine II; leurs procédés de préparation, compositions pharmaceutiques les contenant | |
| US5679677A (en) | Heterocyclic carbamates, process for their preparation and medicaments | |
| WO1997003987A1 (fr) | Nouveaux derives de la galanthamine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant | |
| IE49541B1 (en) | 4,5-dihydro-1-(3-mercapto-1-oxopropyl)-3-phenyl-1h-pyrazole-5-carboxylic acid and derivatives thereof | |
| NZ208896A (en) | Benzazepine and benzoxazepine derivatives and pharmaceutical compositions | |
| EP0077427B1 (fr) | Dérivés de pipéridine, leur procédé de préparation et leur application en thérapeutique | |
| US6297237B1 (en) | Process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity | |
| EP0136198B1 (fr) | Dérivés de triazolo pyrimidine, leur procédé de préparation et leur application thérapeutique en tant que toni-cardiaques | |
| FR2470770A1 (fr) | Nouveaux ethers de b-imidazolylethyle de quinoleine-2 ou 4-methanols, utiles notamment comme antimicrobiens, et leur procede de preparation | |
| US4438121A (en) | Isoquinoline amidoxime derivatives | |
| FI90417B (fi) | Menetelmä terapeuttisesti aktiivisten hydroksi-1,2,3,4-tetrahydroaminoakridiinien valmistamiseksi | |
| FI57589C (fi) | Foerfarande foer framstaellning av blodtrycket saenkande 6-substituerade 3-karbetoksihydrazinopyridaziner | |
| CZ20001294A3 (cs) | Způsob výroby aminokarbonylových derivátů geneserolinu | |
| KR860001583B1 (ko) | 6-아닐리노-5,8-퀴녹살린 디온의 제조방법 | |
| EP0233800A1 (fr) | Dérivés d'imidazo[1,2-a]quinoléines, leur préparation et leur application en thérapeutique | |
| EP0231138B1 (fr) | Dérivés d'acylaminométhyl-1imidazo [1,2-a] quinoléines, leur préparation et leur application en thérapeutique | |
| EP0032856A1 (fr) | Nouveaux dérivés de dihydro-2,3-imidazo(1,2-b)pyridazines, leur procédé de préparation et leur application en thérapeutique | |
| US4612317A (en) | Tetrahydro-β-carboline dithioic acid derivatives and treatment of liver diseases | |
| EP0581767B1 (en) | 5H-DIBENZO(a,d)CYCLOHEPTENES AS MUSCARINIC RECEPTOR ANTAGONISTS | |
| KR880001659B1 (ko) | 1,7-디하이드로-피롤로[3,4-e][1,4]디아제핀-2-(1H)-온 유도체 및 이의 중간체의 제조방법 | |
| CA2086440A1 (en) | Eseroline derivatives having anticholinesterase activity, a process for their preparation and pharmaceutical compositions containing them |